Cheap flights from MEX to DSM (Mexico City Intl. to Des Moines Intl.)
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Cheap Flights from MEX to DSM starting at $326 One Way, $418 Round Trip
Prices starting at $418 for return flights and $326 for one-way flights to Des Moines Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
MEX
Mexico City
DSM
Des Moines
$418 Roundtrip, found 3 days ago
$418
Roundtrip
found 3 days ago
MEX
Mexico City
DSM
Des Moines
$438 Roundtrip, found 3 days ago
$438
Roundtrip
found 3 days ago
MEX
Mexico City
DSM
Des Moines
$476 Roundtrip, found 3 days ago
$476
Roundtrip
found 3 days ago
MEX
Mexico City
DSM
Des Moines
$482 Roundtrip, found 3 days ago
$482
Roundtrip
found 3 days ago
MEX
Mexico City
DSM
Des Moines
$498 Roundtrip, found 3 days ago
$498
Roundtrip
found 3 days ago
Hotel Ideas near Des Moines Intl.
Airport Hotels near Des Moines Intl.
Days Inn & Suites by Wyndham Des Moines Airport
1901 Hackley Ave Des Moines IA
$65 nightly
The price is $73 total per night from Jan 20 to Jan 21
$73 total
Jan 20 - Jan 21
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,702 reviews)
The room was spotless and comfortable. Plenty of hot water. The room we had was quiet and warm. Breakfast started at4:30am. Great for early travelers.
Reviewed on Jan 7, 2026
Quality Inn & Suites Des Moines Airport
5231 Fleur Dr Des Moines IA
$63 nightly
The price is $70 total per night from Jan 27 to Jan 28
$70 total
Jan 27 - Jan 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.2/10 Good! (1,000 reviews)
Great staff very helpful.
Reviewed on Dec 22, 2025
Hampton Inn Des Moines-Airport
5001 Fleur Dr Des Moines IA
$109 nightly
The price is $122 total per night from Jan 26 to Jan 27
$122 total
Jan 26 - Jan 27
Total with taxes and fees
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.8/10 Excellent! (1,000 reviews)
Average No plastic gladd or cup in Bathroom
Reviewed on Jan 4, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels In Des Moines
Hotel Fort Des Moines, Curio Collection by Hilton
1000 Walnut St Des Moines IA
$139 nightly
The price is $155 total per night from Jan 17 to Jan 18
$155 total
Jan 17 - Jan 18
Total with taxes and fees
Book a stay at this luxury hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms ...
9.4/10 Exceptional! (1,075 reviews)
The room is clean and comfortable designed very nicely, check-in was easy. We felt secure and it was very nice and quiet.
Reviewed on Jan 10, 2026
Stoney Creek Hotel Des Moines - Johnston
5291 Stoney Creek Court Johnston IA
$83 nightly
The price is $93 total per night from Jan 28 to Jan 29
$93 total
Jan 28 - Jan 29
Total with taxes and fees
Book a stay at this business-friendly hotel in Johnston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.8/10 Excellent! (1,811 reviews)
Everything was great!
Reviewed on Jan 7, 2026
Fairfield Inn and Suites by Marriott Des Moines West
7225 Vista Dr West Des Moines IA
$83 nightly
The price is $93 total per night from Jan 22 to Jan 23
$93 total
Jan 22 - Jan 23
Total with taxes and fees
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,005 reviews)
Convenient location
Reviewed on Jan 10, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Des Moines Hotels With Airport Transportation
Days Inn & Suites by Wyndham Des Moines Airport
1901 Hackley Ave Des Moines IA
$65 nightly
The price is $73 total per night from Jan 20 to Jan 21
$73 total
Jan 20 - Jan 21
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,702 reviews)
The room was spotless and comfortable. Plenty of hot water. The room we had was quiet and warm. Breakfast started at4:30am. Great for early travelers.
Reviewed on Jan 7, 2026
Quality Inn & Suites Des Moines Airport
5231 Fleur Dr Des Moines IA
$63 nightly
The price is $70 total per night from Jan 27 to Jan 28
$70 total
Jan 27 - Jan 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.2/10 Good! (1,000 reviews)
Great staff very helpful.
Reviewed on Dec 22, 2025
Hampton Inn Des Moines-Airport
5001 Fleur Dr Des Moines IA
$109 nightly
The price is $122 total per night from Jan 26 to Jan 27
$122 total
Jan 26 - Jan 27
Total with taxes and fees
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.8/10 Excellent! (1,000 reviews)
Average No plastic gladd or cup in Bathroom
Reviewed on Jan 4, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Low Priced Des Moines Hotels
Motel 6 West Des Moines, IA
7655 Office Plaza Dr N West Des Moines IA
$51 nightly
The price is $57 total per night from Jan 27 to Jan 28
$57 total
Jan 27 - Jan 28
Total with taxes and fees
Stay at this motel in West Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
7.8/10 Good! (734 reviews)
Yes
Reviewed on Jan 4, 2026
Cozy Rest Motel
2316 Southeast 14th Street Des Moines IA
$70 nightly
The price is $79 total per night from Jan 15 to Jan 16
$79 total
Jan 15 - Jan 16
Total with taxes and fees
Stay at this motel in Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.6/10 Good! (651 reviews)
This was a no frills place to stay but the room was nice and the front desk guy was friendly. If you are looking for a cheap but nice place to stay, check them out.
Reviewed on Sep 25, 2025
Quality Inn
1258 8th St West Des Moines IA
$51 nightly
The price is $57 total per night from Feb 12 to Feb 13
$57 total
Feb 12 - Feb 13
Total with taxes and fees
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6.8/10 (19 reviews)
Room was clean. Nice safe location The front desk person was friendly. Great budget hotel if you’re going to a concert at the Val air ballroom it’s walking distance. across the street You have gas station and a couple fast food options,. This will be my regular hotel for when I go see concerts at ...
Reviewed on Nov 19, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Des Moines
Wildwood Lodge
11431 Forest Ave Clive IA
$95 nightly
The price is $107 total per night from Jan 25 to Jan 26
$107 total
Jan 25 - Jan 26
Total with taxes and fees
Stay at this hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,219 reviews)
Staff courteous, room spotless, easy and quick check in. Loved the games in the lobby and breakfast was delicious- great selection. Beds comfortable. It was perfect stay for our road trip. Will come back again.
Reviewed on Jan 8, 2026
Ramada Tropics Resort & Conf Center by Wyndham Des Moines
5000 Merle Hay Rd Urbandale IA
$70 nightly
The price is $78 total per night from Jan 21 to Jan 22
$78 total
Jan 21 - Jan 22
Total with taxes and fees
Book a stay at this family-friendly hotel in Urbandale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
5.6/10 (684 reviews)
Families like: Kids pool, waterpark, game room, cribs
Travelers say...
Lo único que no me gustó fue que la piscina no estaba funcionado al maximo
Reviewed on Jan 11, 2026
Baymont by Wyndham Des Moines Airport
6221 Willow Creek Ave Des Moines IA
$86 nightly
The price is $96 total per night from Jan 19 to Jan 20
$96 total
Jan 19 - Jan 20
Total with taxes and fees
Book a stay at this family-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
9.2/10 Wonderful! (1,166 reviews)
Families like: Game room, cribs, rollaway beds, games and toys
Travelers say...
Great stay
Reviewed on Jan 3, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
MEX to DSM Route Info
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MEX Address & GPS
Address:
Mexico City ,
Mexico
IATA Code:
MEX
Longitude:
-99.072778
Latitude:
19.435278
Time Zone:
America/Mexico_City
DSM Address & GPS
Address:
5800 Fleur Drive, Suite 201
Des Moines IA, 50321-2854
United States
IATA Code:
DSM
Longitude:
-93.648087
Latitude:
41.532434
Time Zone:
America/Chicago
Other Flights from Mexico City Intl. Airport (MEX)
Other Flights to Des Moines Intl. Airport (DSM)
- Felipe Ángeles Intl. Airport (NLU)
- Toluca Intl. Airport (TLC)
- Hermanos Serdan Intl. Airport (PBC)
- Querétaro Intl. Airport (QRO)
- General Francisco Mujica Intl. Airport (MLM)
- El Tajin National Airport (PAZ)
- El Lencero Airport (JAL)
- Tamuin National Airport (TSL)
- Del Bajío Airport (BJX)
- General Juan N. Alvarez Intl. Airport (ACA)
Frequently asked questions
Map To Nearby Hotels
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.