Orangeburg County Vacation Rentals

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Top cities in Orangeburg County

A calm lake with autumn-colored trees and a clear blue sky.
Vacation RentalsVacation Rentals
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Orangeburg

Orangeburg

Orangeburg County Vacation Rentals

Bells Marina & Resort

Bells Marina & Resort

2.5 out of 5
12907 Old Number Six Hwy Eutawville SC
$77 nightly
The price is $85 total per night
$85 total
Aug 9 - Aug 10
Total with taxes and fees
Renovated in 2025, Bells Marina & Resort offers a marina, a gym, and free WiFi in public areas. You can put free parking to good use if you drive. The front desk has multilingual staff that can answer questions about the accommodations, services, and more. Other amenities at this golf aparthotel include conference space, laundry facilities, and a picnic area.
Pet friendly country cottage with large fenced-in yard & horses on property

Pet friendly country cottage with large fenced-in yard & horses on property

Holly Hill SC
$186 nightly
The price is $206 total per night
$206 total
Aug 4 - Aug 5
Total with taxes and fees
At this cottage, guests have access to features like laundry facilities.
Lakefront Retreat on Lake Marion – Perfect for Fishing & Relaxation

Lakefront Retreat on Lake Marion – Perfect for Fishing & Relaxation

Santee SC
At this condo, guests have access to features like laundry facilities. This smoke-free condo building also has barbecue grills.
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Santee SC
$307 nightly
The price is $341 total per night
$341 total
Aug 10 - Aug 11
Total with taxes and fees
At this vacation home, guests have access to features like laundry facilities. This smoke-free vacation home also has barbecue grills.
Waterfront Lake Marion Retreat • Pool • Gazebo • Minutes from I-95

Waterfront Lake Marion Retreat • Pool • Gazebo • Minutes from I-95

Santee SC
This condo features an outdoor pool and laundry facilities.
Relax by Lake Marion - A lake home with you in mind.

Relax by Lake Marion - A lake home with you in mind.

Eutawville SC
At this vacation home, guests have access to features like laundry facilities. This family-friendly vacation home also has barbecue grills.
Waterfront King Beds Pet Friendly Deck Home with Dock & Views.

Waterfront King Beds Pet Friendly Deck Home with Dock & Views.

Eutawville SC
At this apartment, guests have access to features like laundry facilities. This apartment building also has barbecue grills.
CatDaddy Cabin - Lake Marion Cabin in Santee - lake view, fire pit, boat parking

CatDaddy Cabin - Lake Marion Cabin in Santee - lake view, fire pit, boat parking

Santee SC
Guests staying at this cabin have access to laundry facilities, a garden, and barbecue grills.
Lake Marion Getaway!

Lake Marion Getaway!

Vance SC
Guests staying at this vacation home have access to laundry facilities, barbecue grills, and a garden.
Lake Marion - Majestic Big Water View!

Lake Marion - Majestic Big Water View!

Santee SC
At this condo, guests have access to an outdoor pool, laundry facilities, and barbecue grills.
Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS

Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS

Summerton SC
Guests staying at this vacation home enjoy a gym, an arcade/game room, and laundry facilities. Other amenities at this family-friendly vacation home include a garden and barbecue grills.
Kitchen
Washer
Beautiful lake home to make your family vacation extra special!

Beautiful lake home to make your family vacation extra special!

Summerton SC
At this vacation home, guests have access to features like laundry facilities. This smoke-free vacation home also has a garden.
SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable

SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable

Summerton SC
$571 nightly
The price is $634 total per night
$634 total
Aug 20 - Aug 21
Total with taxes and fees
At this vacation home, guests have access to an arcade/game room, laundry facilities, and barbecue grills. This beach vacation home also has a garden.
Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy

Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy

Manning SC
At this vacation home, guests have access to features like laundry facilities. This smoke-free vacation home also has barbecue grills.
Home With View of Columbia Cityscape

Home With View of Columbia Cityscape

Gaston SC
Guests staying at this vacation home have access to laundry facilities, barbecue grills, and a garden.
2-bedroom cottage in adorable Summerville with AC comfort

2-bedroom cottage in adorable Summerville with AC comfort

Summerville SC
$165 nightly
The price is $178 total per night
$178 total
Aug 16 - Aug 17
Total with taxes and fees
At this cottage, guests have access to features like laundry facilities. This smoke-free cottage also has a garden.
Cottage Tree House B&B

Cottage Tree House B&B

Hopkins SC
At this vacation home, guests have access to barbecue grills.
2 Full Beds|Non-Smoking|Micfridge

2 Full Beds|Non-Smoking|Micfridge

West Columbia SC
Free Cancellation
$73 nightly
The price is $79 total per night
$79 total
Aug 6 - Aug 7
Total with taxes and fees
At this apartment, guests have access to barbecue grills.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Orangeburg County

    Best Western Plus Santee Inn

    Best Western Plus Santee Inn

    I 95 Exit 98 Santee SC
    $119 nightly
    The price is $132 total per night from Aug 9 to Aug 10
    $132 total
    Aug 9 - Aug 10
    Total with taxes and fees
    8.8/10 Excellent! (1,008 reviews)
    Baymont by Wyndham Santee

    Baymont by Wyndham Santee

    249 Britain Street Santee SC
    $80 nightly
    The price is $89 total per night from Aug 4 to Aug 5
    $89 total
    Aug 4 - Aug 5
    Total with taxes and fees
    Tru By Hilton Santee

    Tru By Hilton Santee

    263 Britain St. and 273 Britain St. Santee SC
    $98 nightly
    The price is $108 total per night from Aug 9 to Aug 10
    $108 total
    Aug 9 - Aug 10
    Total with taxes and fees

Orbitz makes it easy to find vacation rentals in Orangeburg County 

🏠 What is the best price for a Orangeburg County vacation rental?


Orangeburg County rentals range between $79 and $634 per night. At Orbitz, we have a vacation rental for every budget.


🏠 What types of vacation rentals in Orangeburg County can I rent?


Choose from apartments to beautifully decorated vacation homes, condo resorts or even B&Bs or motels for your next Orangeburg County getaway. Orbitz filters your search results so you can find the best Orangeburg County vacation rental for you. We have tons of options.


🏠 Are cancellations free on Orangeburg County vacation rentals with Orbitz?


You may be able to cancel or amend your Orangeburg County vacation rental booking free of charge before a pre-agreed deadline. Make sure to check the terms of cancellation before you book—so you know exactly where you stand. 


🏠 How do I find the best vacation rental deals in Orangeburg County?


Enter your travel dates, and we’ll do the rest. You can then browse our exciting deals and all the tempting vacation rentals we have on offer in Orangeburg County by filtering your search by amenities, prices, and property types and look at customers ratings to help you pick.


🏠 How do I cancel my vacation rental booking through Orbitz


Vacation rentals have slightly different rules to other bookings on Orbitz. Usually, you need to contact your property manager, you may be able to get a full refund before the cancellation date. Click My TripsOpens in a new window on your Orbitz account page to find the right information contact. If you need more help, visit our Customer ServiceOpens in a new window page. 


🏠 What are the advantages of booking a vacation rental in Orangeburg County?


When you book a Orangeburg County vacation rental, you have the privacy of home and can add on those luxury amenities of a hotel. Filter your vacation rental results to find a place with a hot tub or pool, games rooms or large patio with a barbecue. With so much choice on offer, it’s easy to plan the perfect trip with Orbitz. 


🏠 Where can I find vacation rentals in Orangeburg County?


Escape back to nature and check out some of the smaller towns. You’ll find great vacation rentals right across Orangeburg County—with plenty of hidden gems. We also have plenty of inventory in Orangeburg County main cities and near popular attraction spots.


🏠 Why should I book my Orangeburg County vacation rental with Orbitz?


At Orbitz, we search the market for the best accommodation, flights, and car rental deals, so you don’t have to. We’ll help you build your dream Orangeburg County vacation. With plenty of vacation rentals on offer, you can be sure to find the one that’s right for you in just a few clicks. 


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