Cheap flights from SDF to EYW (Louisville Intl. to Key West Intl.)

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Cheap Flights from SDF to EYW starting at $271 One Way, $283 Round Trip

Prices starting at $283 for return flights and $271 for one-way flights to Key West Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Mar 3 - Tue, Mar 10
SDF
Louisville
EYW
Key West
$283 Roundtrip, found 2 hours ago
$283
Roundtrip
found 2 hours ago
Select Delta flight, departing Tue, Mar 3 from Louisville to Key West, returning Tue, Mar 10, priced at $283 found 2 hours ago
Tue, Nov 11 - Wed, Nov 19
SDF
Louisville
EYW
Key West
$287 Roundtrip, found 1 day ago
$287
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Nov 11 from Louisville to Key West, returning Wed, Nov 19, priced at $287 found 1 day ago
Mon, Mar 2 - Tue, Mar 10
SDF
Louisville
EYW
Key West
$311 Roundtrip, found 2 hours ago
$311
Roundtrip
found 2 hours ago
Select Delta flight, departing Mon, Mar 2 from Louisville to Key West, returning Tue, Mar 10, priced at $311 found 2 hours ago
Thu, Nov 13 - Tue, Nov 18
SDF
Louisville
EYW
Key West
$316 Roundtrip, found 1 day ago
$316
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Nov 13 from Louisville to Key West, returning Tue, Nov 18, priced at $316 found 1 day ago
Mon, Nov 24 - Mon, Dec 1
SDF
Louisville
EYW
Key West
$326 Roundtrip, found 5 days ago
$326
Roundtrip
found 5 days ago
Select Delta flight, departing Mon, Nov 24 from Louisville to Key West, returning Mon, Dec 1, priced at $326 found 5 days ago

Hotel Ideas near Key West Intl.

Airport Hotels near Key West Intl.

Hyatt Vacation Club at Windward Pointe, Key West

Hyatt Vacation Club at Windward Pointe, Key West

3.5 out of 5
3675 South Roosevelt Boulevard, Key West, FL
$241 nightly
The price is $272 total per night from Oct 6 to Oct 7
$272 total
Oct 6 - Oct 7
Total with taxes and fees
Stay at this 3.5-star eco-certified hotel in Key West. Enjoy free WiFi, free parking, and a snack bar/deli. Our guests praise the pool and the helpful staff ...
9.4/10 Exceptional! (1,032 reviews)
"Staff was lovely. Check in and check out we’re both painless and quick. One girl at the front desk upon check in was rude to another guest which was highly inappropriate in front of other guests but switched over to take care of our check in and was very pleasant. Grounds were well kept and clean. ..."

Reviewed on Sep 25, 2025

Hyatt Vacation Club at Windward Pointe, Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd, Key West, FL
$159 nightly
The price is $179 total per night from Oct 7 to Oct 8
$179 total
Oct 7 - Oct 8
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,248 reviews)
"The staff was great. Breakfast was abundant and good."

Reviewed on Sep 27, 2025

Hampton Inn Key West FL
DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd, Key West, FL
$149 nightly
The price is $168 total per night from Oct 6 to Oct 7
$168 total
Oct 6 - Oct 7
Total with taxes and fees
Stay at this 4-star business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
7.8/10 Good! (1,013 reviews)
"Staff very attentive to our needs"

Reviewed on Sep 24, 2025

DoubleTree Resort by Hilton Grand Key - Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Key West

Margaritaville Beach House Key West

Margaritaville Beach House Key West

4 out of 5
2001 South Roosevelt Boulevard, Key West, FL
$235 nightly
The price is $264 total per night from Oct 13 to Oct 14
$264 total
Oct 13 - Oct 14
Total with taxes and fees
Stay at this 4-star beach hotel in Key West. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the pool and the restaurant ...
8.6/10 Excellent! (1,790 reviews)
"We went during off peak season and it was amazing and quiet, relaxing."

Reviewed on Sep 23, 2025

Margaritaville Beach House Key West
Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street, Key West, FL
$229 nightly
The price is $258 total per night from Oct 29 to Oct 30
$258 total
Oct 29 - Oct 30
Total with taxes and fees
Stay at this 4-star beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the bar in our reviews. ...
8.6/10 Excellent! (2,785 reviews)
"The three pools were amazing. We particularly enjoyed the tranquility pool for a quieter or relaxed experience. Lots of great activities and good communication via text from the hotel throughout the stay. Walkable to many of the must see Key West destinations."

Reviewed on Sep 27, 2025

Southernmost Beach Resort and Guesthouses
Oceans Edge Key West Resort, Hotel & Marina

Oceans Edge Key West Resort, Hotel & Marina

4 out of 5
5950 Peninsular Avenue, Key West, FL
$206 nightly
The price is $232 total per night from Oct 29 to Oct 30
$232 total
Oct 29 - Oct 30
Total with taxes and fees
Stay at this 4-star luxury hotel in Key West. Enjoy free WiFi, 6 outdoor pools, and a marina. Our guests praise the pool and the restaurant in our reviews. Popular ...
8.8/10 Excellent! (1,738 reviews)
"Very good for visiting"

Reviewed on Sep 27, 2025

Oceans Edge Key West Resort, Hotel & Marina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Key West Hotels With Airport Transportation

DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd, Key West, FL
$149 nightly
The price is $168 total per night from Oct 6 to Oct 7
$168 total
Oct 6 - Oct 7
Total with taxes and fees
Stay at this 4-star business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
7.8/10 Good! (1,013 reviews)
"Staff very attentive to our needs"

Reviewed on Sep 24, 2025

DoubleTree Resort by Hilton Grand Key - Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd, Key West, FL
$159 nightly
The price is $179 total per night from Oct 7 to Oct 8
$179 total
Oct 7 - Oct 8
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,248 reviews)
"The staff was great. Breakfast was abundant and good."

Reviewed on Sep 27, 2025

Hampton Inn Key West FL
Eden House

Eden House

3.5 out of 5
1015 Fleming St, Key West, FL
$170 nightly
The price is $192 total per night from Sep 30 to Oct 1
$192 total
Sep 30 - Oct 1
Total with taxes and fees
Stay at this 3.5-star hotel in Key West. Enjoy free WiFi, in-room massages, and a 24-hour front desk. Our guests praise the pool and the helpful staff in our ...
9/10 Wonderful! (1,011 reviews)
"Perfect location! GREAT and friendly staff! Rooms were clean and nice! We will definitely be back!"

Reviewed on Sep 23, 2025

Eden House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Key West Hotels

Southwinds Motel

Southwinds Motel

2 out of 5
1321 Simonton Street, Key West, FL
$150 nightly
The price is $169 total per night from Sep 30 to Oct 1
$169 total
Sep 30 - Oct 1
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and a 24-hour front desk. Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,188 reviews)
"Hotel is amazing has everything you need. Pools are clean. Service is amazing"

Reviewed on Sep 25, 2025

Southwinds Motel
Seashell Motel & Key West Hostel

Seashell Motel & Key West Hostel

1.5 out of 5
718 South Street, Key West, FL
$109 nightly
The price is $123 total per night from Oct 2 to Oct 3
$123 total
Oct 2 - Oct 3
Total with taxes and fees
Stay at this hostel in Key West. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7.8/10 Good! (1,009 reviews)
"The room was clean and appeared to have been recently updated. Very nice. There was construction in the pool area, which would have neen nice to know prior to booking. They were renovating other rooms as early as 7am and worked on them as late as 10pm. A little annoying. Overall is was still a good ..."

Reviewed on Sep 23, 2025

Seashell Motel & Key West Hostel
Duval House

Duval House

3 out of 5
815 Duval St, Key West, FL
$131 nightly
The price is $144 total per night from Sep 30 to Oct 1
$144 total
Sep 30 - Oct 1
Total with taxes and fees
Stay at this 3-star B&B in Key West. Enjoy parking (surcharge), daily housekeeping, and a garden. Our guests praise the breakfast and the pool in our reviews. ...
9.4/10 Exceptional! (1,029 reviews)
"Everything was 10/10. Thank you very much, will be staying here again!"

Reviewed on Sep 28, 2025

Duval House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Key West

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street, Key West, FL
$229 nightly
The price is $258 total per night from Oct 29 to Oct 30
$258 total
Oct 29 - Oct 30
Total with taxes and fees
Stay at this 4-star beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the bar in our reviews. ...
8.6/10 Excellent! (2,785 reviews)
"The three pools were amazing. We particularly enjoyed the tranquility pool for a quieter or relaxed experience. Lots of great activities and good communication via text from the hotel throughout the stay. Walkable to many of the must see Key West destinations."

Reviewed on Sep 27, 2025

Southernmost Beach Resort and Guesthouses
Margaritaville Beach House Key West

Margaritaville Beach House Key West

4 out of 5
2001 South Roosevelt Blvd, Key West, FL
Stay at this 4-star beach hotel in Key West. Enjoy free parking, 2 restaurants, and breakfast (surcharge). Popular attractions Duval Street and Smathers Beach ...
8.2/10 Very Good! (1,000 reviews)

Families like: Outdoor pool, babysitting, close to beach, bicycle rentals

Travelers say...
"Stayed here many times. Easy in and out, plenty of parking. Great friendly staff"

Reviewed on Sep 1, 2025

Get rates
Margaritaville Beach House Key West
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard, Key West, FL
$156 nightly
The price is $176 total per night from Sep 30 to Oct 1
$176 total
Sep 30 - Oct 1
Total with taxes and fees
Stay at this 4-star eco-certified hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff in ...
7.8/10 Good! (1,598 reviews)

Families like: Outdoor pools, miniature golf, game room, bicycle rentals

Travelers say...
"The property was amazing I will be coming back and enjoying the other amenities that I don’t get the chance to do so"

Reviewed on Sep 28, 2025

Blue Flamingo Resort Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

SDF to EYW Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
SDF Address & GPS
Address:
600 Terminal Drive
Louisville KY, 40209
United States
IATA Code:
SDF
Longitude:
-85.73599
Latitude:
38.174397
Time Zone:
America/New_York
EYW Address & GPS
Address:
3491 South Roosevelt Boulevard
Key West FL, 33040-5260
United States
IATA Code:
EYW
Longitude:
-81.75501
Latitude:
24.553574
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from SDF to Key West Intl. Airport (EYW)?
Flying from Louisville Muhammad Ali Intl. Airport to Key West Intl. Airport (EYW) means you'll have to switch planes. But hey — there's no need to worry. American Airlines, United Airlines and Delta Air Lines offer flights with only one simple stopover.
What is the shortest flight from SDF to EYW?
The quickest flight from Louisville to Key West is 5 hours and 4 minutes. Grab a refreshment from the drink cart, hone your travel itinerary or get to know your seat mate — you'll have plenty of time on this medium-haul journey.
How many hours flight from Louisville Muhammad Ali Intl. Airport to EYW?
Make yourself comfortable, because a typical plane ride from Louisville Muhammad Ali Intl. Airport to Key West Intl. Airport (EYW) is 5 hours and 7 minutes. Watch a few movies, stick your nose in a book ... There's plenty of time to sit back and enjoy the ride.
What airlines have the most flights from Louisville Intl. Airport (SDF) to EYW?
At the moment, no airlines operate direct flights between Louisville Muhammad Ali Intl. Airport and Key West Intl. Airport (EYW). But don't panic! There are several single or multi-stop options available.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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