Cheap flights from SAT to DSM (San Antonio Intl. to Des Moines Intl.)

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Cheap Flights from SAT to DSM starting at $141 One Way, $179 Round Trip

Prices starting at $179 for return flights and $141 for one-way flights to Des Moines Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Nov 6 - Thu, Nov 13
SAT
San Antonio
DSM
Des Moines
$179 Roundtrip, found 4 days ago
$179
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Thu, Nov 6 from San Antonio to Des Moines, returning Thu, Nov 13, priced at $179 found 4 days ago
Sat, Nov 8 - Thu, Nov 13
SAT
San Antonio
DSM
Des Moines
$230 Roundtrip, found 4 days ago
$230
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Sat, Nov 8 from San Antonio to Des Moines, returning Thu, Nov 13, priced at $230 found 4 days ago
Sun, Nov 9 - Thu, Nov 13
SAT
San Antonio
DSM
Des Moines
$262 Roundtrip, found 4 days ago
$262
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Sun, Nov 9 from San Antonio to Des Moines, returning Thu, Nov 13, priced at $262 found 4 days ago
Tue, Feb 10 - Wed, Feb 18
SAT
San Antonio
DSM
Des Moines
$313 Roundtrip, found 4 days ago
$313
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, Feb 10 from San Antonio to Des Moines, returning Wed, Feb 18, priced at $313 found 4 days ago
Tue, Jan 20 - Tue, Feb 3
SAT
San Antonio
DSM
Des Moines
$315 Roundtrip, found 1 day ago
$315
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Jan 20 from San Antonio to Des Moines, returning Tue, Feb 3, priced at $315 found 1 day ago

Hotel Ideas near Des Moines Intl.

Airport Hotels near Des Moines Intl.

Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave, Des Moines, IA
$68 nightly
The price is $76 total per night from Nov 18 to Nov 19
$76 total
Nov 18 - Nov 19
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,646 reviews)
Close to airport

Reviewed on Nov 2, 2025

Days Inn & Suites by Wyndham Des Moines Airport
AmericInn by Wyndham Des Moines Airport

AmericInn by Wyndham Des Moines Airport

2.5 out of 5
1920 Hackley Ave, Des Moines, IA
$62 nightly
The price is $70 total per night from Nov 25 to Nov 26
$70 total
Nov 25 - Nov 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (1,021 reviews)
Nice place to stay

Reviewed on Oct 25, 2025

AmericInn by Wyndham Des Moines Airport
Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport

2.5 out of 5
5001 Fleur Dr, Des Moines, IA
$114 nightly
The price is $128 total per night from Nov 16 to Nov 17
$128 total
Nov 16 - Nov 17
Total with taxes and fees
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.6/10 Excellent! (1,006 reviews)
easy to find in the rain. helpful front desk. clean room, and public areas.

Reviewed on Nov 2, 2025

Hampton Inn Des Moines-Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Des Moines

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St, Des Moines, IA
$139 nightly
The price is $155 total per night from Nov 9 to Nov 10
$155 total
Nov 9 - Nov 10
Total with taxes and fees
Stay at this 4.5-star luxury hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (1,051 reviews)
Super comfy beds and linen, clean, and nicely designed rooms!

Reviewed on Nov 3, 2025

Hotel Fort Des Moines, Curio Collection by Hilton
Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave, Des Moines, IA
$68 nightly
The price is $76 total per night from Nov 18 to Nov 19
$76 total
Nov 18 - Nov 19
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,646 reviews)
Close to airport

Reviewed on Nov 2, 2025

Days Inn & Suites by Wyndham Des Moines Airport
Motel 6 West Des Moines, IA

Motel 6 West Des Moines, IA

2 out of 5
7655 Office Plaza Dr N, West Des Moines, IA
$51 nightly
The price is $57 total per night from Nov 17 to Nov 18
$57 total
Nov 17 - Nov 18
Total with taxes and fees
Stay at this motel in West Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
7.6/10 Good! (648 reviews)
Very clean quiet and love the staff especially the front desk gentlman sian

Reviewed on Oct 30, 2025

Motel 6 West Des Moines, IA
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Des Moines Hotels With Airport Transportation

Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave, Des Moines, IA
$68 nightly
The price is $76 total per night from Nov 18 to Nov 19
$76 total
Nov 18 - Nov 19
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,646 reviews)
Close to airport

Reviewed on Nov 2, 2025

Days Inn & Suites by Wyndham Des Moines Airport
Quality Inn & Suites Des Moines Airport

Quality Inn & Suites Des Moines Airport

2.5 out of 5
5231 Fleur Dr, Des Moines, IA
$63 nightly
The price is $71 total per night from Nov 10 to Nov 11
$71 total
Nov 10 - Nov 11
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.2/10 Good! (1,004 reviews)
Room was clean and bed very comfortable.

Reviewed on Nov 3, 2025

Quality Inn & Suites Des Moines Airport
Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport

2.5 out of 5
5001 Fleur Dr, Des Moines, IA
$114 nightly
The price is $128 total per night from Nov 16 to Nov 17
$128 total
Nov 16 - Nov 17
Total with taxes and fees
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.6/10 Excellent! (1,006 reviews)
easy to find in the rain. helpful front desk. clean room, and public areas.

Reviewed on Nov 2, 2025

Hampton Inn Des Moines-Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Des Moines Hotels

Motel 6 West Des Moines, IA

Motel 6 West Des Moines, IA

2 out of 5
7655 Office Plaza Dr N, West Des Moines, IA
$51 nightly
The price is $57 total per night from Nov 17 to Nov 18
$57 total
Nov 17 - Nov 18
Total with taxes and fees
Stay at this motel in West Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
7.6/10 Good! (648 reviews)
Very clean quiet and love the staff especially the front desk gentlman sian

Reviewed on Oct 30, 2025

Motel 6 West Des Moines, IA
Cozy Rest Motel

Cozy Rest Motel

2 out of 5
2316 Southeast 14th Street, Des Moines, IA
$69 nightly
The price is $78 total per night from Nov 5 to Nov 6
$78 total
Nov 5 - Nov 6
Total with taxes and fees
Stay at this motel in Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.6/10 Good! (648 reviews)
This was a no frills place to stay but the room was nice and the front desk guy was friendly. If you are looking for a cheap but nice place to stay, check them out.

Reviewed on Sep 25, 2025

Cozy Rest Motel
Quality Inn

Quality Inn

2 out of 5
1258 8th St, West Des Moines, IA
$60 nightly
The price is $67 total per night from Dec 3 to Dec 4
$67 total
Dec 3 - Dec 4
Total with taxes and fees
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
7.2/10 Good! (8 reviews)
The manager/owner was so polite abd smiled. Gave me a comfortable feel. The rooms were clean and fresh. Slept well. Quiet. Will be checking in here again

Reviewed on Nov 1, 2025

Quality Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Des Moines

Wildwood Lodge

Wildwood Lodge

3 out of 5
11431 Forest Ave, Clive, IA
$113 nightly
The price is $127 total per night from Nov 25 to Nov 26
$127 total
Nov 25 - Nov 26
Total with taxes and fees
Stay at this 3-star hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.4/10 Exceptional! (1,224 reviews)
Staff was courteous. Clean quiet room. Great options on breakfast buffet. Nice vibe overall at this property.

Reviewed on Nov 3, 2025

Wildwood Lodge
Ramada Tropics Resort & Conf Center by Wyndham Des Moines

Ramada Tropics Resort & Conf Center by Wyndham Des Moines

3 out of 5
5000 Merle Hay Rd, Urbandale, IA
$66 nightly
The price is $73 total per night from Nov 6 to Nov 7
$73 total
Nov 6 - Nov 7
Total with taxes and fees
Book a stay at this family-friendly hotel in Urbandale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
5.6/10 (642 reviews)

Families like: Kids pool, waterpark, game room, cribs

Travelers say...
Love the staff. This is my second time in the last 30 days. We take the grandkids there. The front desk staff and bar staff are amazing!!!

Reviewed on Oct 26, 2025

Ramada Tropics Resort & Conf Center by Wyndham Des Moines
Baymont by Wyndham Des Moines Airport

Baymont by Wyndham Des Moines Airport

2.5 out of 5
6221 Willow Creek Ave, Des Moines, IA
$72 nightly
The price is $81 total per night from Nov 30 to Dec 1
$81 total
Nov 30 - Dec 1
Total with taxes and fees
Book a stay at this family-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
9.2/10 Wonderful! (1,118 reviews)

Families like: Game room, cribs, rollaway beds, games and toys

Travelers say...
Quiet stay with nice amenities. Whirlpool wasnt as hot as expected and they overused the chlorine. Otherwise, a very nice stay. Would love to see the addition of a fruit topping for the waffles/pancakes, or a potato option.

Reviewed on Oct 26, 2025

Baymont by Wyndham Des Moines Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

SAT to DSM Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date

Frequently asked questions

Are there non-stop flights from San Antonio Intl. Airport (SAT) to Des Moines Intl. Airport (DSM)?
Unfortunately, direct flights aren't an option when traveling from SAT to Des Moines Intl. Airport (DSM). However, there are numerous carriers that operate on this route with only one easy stopover, including American Airlines, United Airlines and Delta Air Lines.
What is the shortest flight from San Antonio Intl. Airport (SAT) to Des Moines Intl. Airport (DSM)?
From San Antonio, the eclectic sights and sounds of Des Moines are around 4 hours and 38 minutes away. Book your favorite seat, or perhaps even upgrade to one with more legroom, and travel to your destination in pure comfort.
How many hours flight from SAT to Des Moines Intl. Airport?
Get cozy, because the average flight time from SAT to Des Moines Intl. Airport (DSM) is 4 hours and 43 minutes. Watch a few TV episodes, finish that book … You'll have plenty of time to sit back and enjoy the ride.
What airlines have the most flights from SAT to Des Moines Intl. Airport (DSM)?
For now, you can't fly nonstop between San Antonio and Des Moines. However, you will be able to book flights with at least one stop. There's always a silver lining — use the break to get the blood flowing again or go in search of a nice meal!

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.