Cheap flights from TYS to COU (McGhee Tyson to Columbia Regional)
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Cheap Flights from TYS to COU starting at $273 One Way, Round Trip
Prices starting at for return flights and $273 for one-way flights to Columbia Regional were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Hotel Ideas near Columbia Regional
Airport Hotels near Columbia Regional
Whispering Woods Hideaway ~ Large Home ~ 85 in TV
Columbia MO
$453 nightly
The price is $476 total per night from Oct 4 to Oct 5
$476 total
Oct 4 - Oct 5
Total with taxes and fees
Stay at this vacation home in Columbia. Enjoy free WiFi, laundry facilities, and patios. Popular attractions Rock Bridge Memorial State Park and Three Creeks ...
10/10 Exceptional! (5 reviews)
"Loved the location and very clean"
Reviewed on Aug 14, 2026
3-bedroom Ranch Duplex in charming Columbia with WiFi, 6 miles to Mizzou Arena
Columbia MO
$324 nightly
The price is $341 total per night from Oct 5 to Oct 6
$341 total
Oct 5 - Oct 6
Total with taxes and fees
Stay at this vacation home in Columbia. Enjoy free WiFi, laundry facilities, and patios. Popular attractions Gans Creek Conservation Area and Philips Lake are ...
9.6/10 Exceptional! (15 reviews)
"We really enjoyed our stay at this lovely, clean, and comfortable 3-bedroom, 2-bathroom duplex. There were three of us, but the space is roomy enough to comfortably accommodate a larger group. Everything was just as advertised, and the kitchen was fully stocked with everything we needed. There were ..."
Reviewed on Aug 24, 2026
Tru By Hilton Columbia South
4401 S Ponderosa Street Columbia MO
$89 nightly
The price is $102 total per night from Oct 27 to Oct 28
$102 total
Oct 27 - Oct 28
Total with taxes and fees
Stay at this hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions A. Perry Philips Park and Philips Lake are located ...
9.2/10 Wonderful! (141 reviews)
"Great new hotel. Close to the Ganz Creek Cross Country course!"
Reviewed on Sep 30, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels In Columbia
Baymont by Wyndham Columbia, MO
2500 I 70 Dr Sw Columbia MO
$60 nightly
The price is $67 total per night from Oct 11 to Oct 12
$67 total
Oct 11 - Oct 12
Total with taxes and fees
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
8.2/10 Very Good! (1,058 reviews)
"After a long drive we planned a dyop at this hotel. Heather at the front desk greeted us with a warm smile, quickly checked us in and was helpful with suggestions for places to eat. The room was immaculate and quiet. We appreciated the breakfast in the morning so we could get back on the road. The ..."
Reviewed on Oct 1, 2026
Drury Plaza Hotel Columbia East
3100 Interstate 70 Dr. SE Columbia MO
$102 nightly
The price is $115 total per night from Oct 11 to Oct 12
$115 total
Oct 11 - Oct 12
Total with taxes and fees
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the breakfast and ...
9.6/10 Exceptional! (1,660 reviews)
"Excellent hotel. Both breakfast and the free supper were great. Friendly staff. Clean, well maintained property. The pool is a bit boring, especially if the divider is closed. Pool is 3 ft deep on both ends, and 5 ft in the middle."
Reviewed on Sep 29, 2026
Stoney Creek Hotel Columbia
2601 S Providence Rd Columbia MO
$115 nightly
The price is $130 total per night from Oct 25 to Oct 26
$130 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the breakfast and the pool in ...
8.6/10 Excellent! (1,404 reviews)
"This is a unique style place with solid service."
Reviewed on Oct 1, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Columbia Hotels With Airport Transportation
Courtyard by Marriott Columbia Missouri
3301 LeMone Industrial Blvd Columbia MO
$114 nightly
The price is $129 total per night from Oct 11 to Oct 12
$129 total
Oct 11 - Oct 12
Total with taxes and fees
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Walters-Boone County Historic ...
8.6/10 Excellent! (708 reviews)
"Great staff"
Reviewed on Sep 27, 2026
Stoney Creek Hotel Columbia
2601 S Providence Rd Columbia MO
$115 nightly
The price is $130 total per night from Oct 25 to Oct 26
$130 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the breakfast and the pool in ...
8.6/10 Excellent! (1,404 reviews)
"This is a unique style place with solid service."
Reviewed on Oct 1, 2026
The Broadway Columbia - a DoubleTree by Hilton
1111 E Broadway Columbia MO
$156 nightly
The price is $177 total per night from Nov 1 to Nov 2
$177 total
Nov 1 - Nov 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, 2 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff in our ...
9.4/10 Exceptional! (1,000 reviews)
"Getting between towers and to higher parking levels was not easy with luggage. We ended up having to park on top level and had difficulty with elevator and had to walk up last 2 levels when leaving."
Reviewed on Sep 28, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Low Priced Columbia Hotels
Baymont by Wyndham Kingdom City
5750 Jade Rd Kingdom City MO
$107 nightly
The price is $120 total per night from Oct 4 to Oct 5
$120 total
Oct 4 - Oct 5
Total with taxes and fees
Book a stay at this business-friendly motel in Kingdom City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Ramada by Wyndham Columbia
901 Conley Rd Columbia MO
$69 nightly
The price is $78 total per night from Oct 4 to Oct 5
$78 total
Oct 4 - Oct 5
Total with taxes and fees
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.4/10 Good! (1,000 reviews)
"Smelled like smoke."
Reviewed on Sep 27, 2026
Budget Inn
1309 Jefferson St Jefferson City MO
$65 nightly
The price is $75 total per night from Oct 4 to Oct 5
$75 total
Oct 4 - Oct 5
Total with taxes and fees
Stay at this motel in Jefferson City. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Hickory Adams Park and McKay Park are located ...
6/10 (154 reviews)
"Room was small, floor was dirty. Baseboards in bathroom were awful. No place to put suitcases, only one chair with the table that had a broken leg,that if you moved it closer to the bed so my wife could sit at the table with me, you had to hold it. The staff were very pleasant. But it was not worth ..."
Reviewed on Sep 28, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Columbia
Glenn Acres Farm, Fishing and Relaxing, a Place Everyone Loves!
Columbia MO
Stay at this vacation home in Columbia. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Lakeview Mall and Eastport Park are located ...
9.8/10 Exceptional! (102 reviews)
"Beautiful home & beautiful property. Minutes from the highway. Would come back again!"
Reviewed on Jun 28, 2026
Wingate by Wyndham - Columbia
3101 Wingate Ct Columbia MO
$86 nightly
The price is $97 total per night from Oct 11 to Oct 12
$97 total
Oct 11 - Oct 12
Total with taxes and fees
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Country Inn & Suites by Radisson, Columbia, MO
817 N Keene St Columbia MO
$84 nightly
The price is $95 total per night from Oct 25 to Oct 26
$95 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
TYS to COU Route Info
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TYS Address & GPS
Address:
2055 Alcoa Highway
Knoxville TN, 37701
United States
IATA Code:
TYS
Longitude:
-83.989729
Latitude:
35.80565
Time Zone:
America/New_York
COU Address & GPS
Address:
Route 1
Columbia MO, 65201
United States
IATA Code:
COU
Longitude:
-92.219167
Latitude:
38.813611
Time Zone:
America/Chicago
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Frequently asked questions
Map To Nearby Hotels
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.