Cheap flights from SAN to STL (San Diego Intl. to Lambert-St. Louis Intl.)

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Cheap Flights from SAN to STL starting at $121 One Way, $215 Round Trip

Prices starting at $215 for return flights and $121 for one-way flights to Lambert-St. Louis Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Jun 3 - Tue, Jun 9
SAN
San Diego
STL
St. Louis
$215 Roundtrip, found 3 days ago
$215
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Wed, Jun 3 from San Diego to St. Louis, returning Tue, Jun 9, priced at $215 found 3 days ago
Tue, Jul 14 - Sat, Jul 18
SAN
San Diego
STL
St. Louis
$224 Roundtrip, found 3 days ago
$224
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Tue, Jul 14 from San Diego to St. Louis, returning Sat, Jul 18, priced at $224 found 3 days ago
Thu, Jun 4 - Wed, Jun 10
SAN
San Diego
STL
St. Louis
$230 Roundtrip, found 4 days ago
$230
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Thu, Jun 4 from San Diego to St. Louis, returning Wed, Jun 10, priced at $230 found 4 days ago
Tue, Jul 14 - Sat, Jul 18
SAN
San Diego
STL
St. Louis
$230 Roundtrip, found 3 days ago
$230
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Tue, Jul 14 from San Diego to St. Louis, returning Sat, Jul 18, priced at $230 found 3 days ago
Fri, May 29 - Sun, May 31
SAN
San Diego
STL
St. Louis
$297 Roundtrip, found 11 hours ago
$297
Roundtrip
found 11 hours ago
Select United flight, departing Fri, May 29 from San Diego to St. Louis, returning Sun, May 31, priced at $297 found 11 hours ago

Hotel Ideas near Lambert-St. Louis Intl.

Airport Hotels near Lambert-St. Louis Intl.

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
$90 nightly
The price is $106 total per night from Jun 7 to Jun 8
$106 total
Jun 7 - Jun 8
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Pear Tree Inn St. Louis Airport
Drury Inn & Suites St. Louis Airport

Drury Inn & Suites St. Louis Airport

3 out of 5
10490 Natural Bridge Rd St. Louis MO
$124 nightly
The price is $145 total per night from Jun 14 to Jun 15
$145 total
Jun 14 - Jun 15
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,235 reviews)
Breakfast and dinner were surprisingly good. Real happy with the stay

Reviewed on May 15, 2026

Drury Inn & Suites St. Louis Airport
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road St. Louis MO
$127 nightly
The price is $149 total per night from May 30 to May 31
$149 total
May 30 - May 31
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.4/10 Very Good! (1,082 reviews)
It was entirely too loud. Parties taking place in our hallway. Nice room, but staff has no control over late night guests. We won’t stay here again.

Reviewed on May 13, 2026

Renaissance St. Louis Airport Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In St. Louis

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
$127 nightly
The price is $149 total per night from May 25 to May 26
$149 total
May 25 - May 26
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (4,036 reviews)
Good location, staff didn't seem to know the area well. Room was clean. Elevators seemed to need serviced.

Reviewed on May 16, 2026

Hyatt Regency St. Louis at The Arch
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
$116 nightly
The price is $136 total per night from Jun 1 to Jun 2
$136 total
Jun 1 - Jun 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
8.4/10 Very Good! (2,216 reviews)
Room was ok need some cleaning due to dusty floors. Find bunch of hair in the shower by the drains.

Reviewed on May 16, 2026

Hollywood Casino & Hotel St. Louis
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive Fenton MO
$89 nightly
The price is $103 total per night from May 18 to May 19
$103 total
May 18 - May 19
Total with taxes and fees
Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,276 reviews)
This is a former Drury and the building is in great shape. Rates were reasonable, breakfast was tasty, staff was cordial. Didn't do much else here, on a road trip and just an overnight stay. Just off I-44 so convenient...although the frontage road and eastbound 44 were a mess on a Friday morning...glad ...

Reviewed on May 16, 2026

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

St. Louis Hotels With Airport Transportation

Quality Inn Saint Louis Airport

Quality Inn Saint Louis Airport

2.5 out of 5
10232 Natural Bridge Rd St. Louis MO
$73 nightly
The price is $85 total per night from Jun 14 to Jun 15
$85 total
Jun 14 - Jun 15
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a free airport shuttle, and parking (surcharge). Our guests praise the helpful staff ...
6.2/10 (1,005 reviews)
Es un hotel de paso si solo quieres llegar a dormir pero el hotel está muy viejo aún que lo remodelaron el baño no me gustó porque la tina tenía óxido en la coladera el lavabo súper bajito

Reviewed on May 16, 2026

Quality Inn Saint Louis Airport
Marriott St. Louis Airport

Marriott St. Louis Airport

4 out of 5
10700 Pear Tree Lane St. Louis MO
$152 nightly
The price is $181 total per night from May 29 to May 30
$181 total
May 29 - May 30
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy breakfast (surcharge), a free airport shuttle, and room service. Our guests praise the helpful ...
8/10 Very Good! (1,001 reviews)
Room was clean. Staff was horrible. Breakfast was took expensive, we thought breakfast came with the room but no you have to buy for like $28 per person

Reviewed on May 15, 2026

Marriott St. Louis Airport
Hilton St. Louis Airport

Hilton St. Louis Airport

3.5 out of 5
10330 Natural Bridge Rd St. Louis MO
$144 nightly
The price is $171 total per night from May 23 to May 24
$171 total
May 23 - May 24
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy 2 restaurants, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
7.6/10 Good! (1,007 reviews)
No refrigerator in room. You must go on a list for a refrigerator. When enough people check out you can have one of their refrigerators. It’s a terribly old hotel, the furnishings are old, the equipment old and noisy. Not what you would expect from a Hilton property.

Reviewed on May 15, 2026

Hilton St. Louis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced St. Louis Hotels

Quality Inn Saint Louis Airport

Quality Inn Saint Louis Airport

2.5 out of 5
10232 Natural Bridge Rd St. Louis MO
$73 nightly
The price is $85 total per night from Jun 14 to Jun 15
$85 total
Jun 14 - Jun 15
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a free airport shuttle, and parking (surcharge). Our guests praise the helpful staff ...
6.2/10 (1,005 reviews)
Es un hotel de paso si solo quieres llegar a dormir pero el hotel está muy viejo aún que lo remodelaron el baño no me gustó porque la tina tenía óxido en la coladera el lavabo súper bajito

Reviewed on May 16, 2026

Quality Inn Saint Louis Airport
Americas Best Value Inn St. Louis Downtown

Americas Best Value Inn St. Louis Downtown

2 out of 5
1100 Lumiere Place Boulevard St. Louis MO
$84 nightly
The price is $98 total per night from May 17 to May 18
$98 total
May 17 - May 18
Total with taxes and fees
Stay at this motel in St. Louis. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Gateway Arch and Busch Stadium are located ...
5.6/10 (842 reviews)
Hotel room i stayed had multiple issues that were not resolved. I was not told that the maintenance person was out.. finally moved to another room that has no cold water in shower.

Reviewed on May 13, 2026

Americas Best Value Inn St. Louis Downtown
OYO Hotel St. Louis Downtown City Center MO

OYO Hotel St. Louis Downtown City Center MO

3.5 out of 5
400 S 14th St St. Louis MO
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff and ...
6.6/10 (1,000 reviews)
Definitely an older hotel. Overall the room was kinda dingy.

Reviewed on Apr 11, 2024

Get rates
OYO Hotel St. Louis Downtown City Center MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in St. Louis

Days Inn by Wyndham St. Louis Lindbergh Boulevard

Days Inn by Wyndham St. Louis Lindbergh Boulevard

2.5 out of 5
South Lindbergh Boulevard, 3660 St. Louis MO
Book a stay at this family-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a nightclub. Popular attractions Laumeier Sculpture Park and Magic ...

Families like: Indoor pool, playground, game room, cribs

Get rates
Days Inn by Wyndham St. Louis Lindbergh Boulevard
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
$145 nightly
The price is $170 total per night from May 25 to May 26
$170 total
May 25 - May 26
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in our ...
9.4/10 Exceptional! (3,413 reviews)
Everything was perfect

Reviewed on May 16, 2026

Drury Plaza Hotel St. Louis at the Arch
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
$116 nightly
The price is $136 total per night from May 25 to May 26
$136 total
May 25 - May 26
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.8/10 Excellent! (1,963 reviews)
The only thing I could have a negative comment on was the bathroom was tiny and the vanity tiny also. But the people were so kind and friendly. Overall a good experience.

Reviewed on May 15, 2026

Pear Tree Inn St. Louis Near Union Station
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

SAN to STL Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
SAN Address & GPS
Address:
Airport Drive
San Diego CA, 92101
United States
IATA Code:
SAN
Longitude:
-117.197312
Latitude:
32.731938
Time Zone:
America/Los_Angeles
STL Address & GPS
Address:
10701 Lambert International Blvd.
Saint Louis MO, 63145
United States
IATA Code:
STL
Longitude:
-90.379002
Latitude:
38.748707
Time Zone:
America/Chicago

Frequently asked questions

Are there non-stop flights from San Diego Intl. Airport (SAN) to Lambert Field?
The wonderful news is Southwest Airlines flies nonstop from San Diego to St. Louis, so you won't have to worry about stepping off the plane until you get to the terminal at Lambert Field.
What is the shortest flight from SAN to St. Louis Lambert International Airport?
The fastest you can fly from San Diego Intl. Airport (SAN) to Lambert Field is 5 hours and 31 minutes. Slip a few things into your carry-on to keep you entertained, like a gripping read or your travel journal.
How many hours flight from San Diego Intl. Airport (SAN) to St. Louis Lambert International Airport?
Settle in and get comfy, because the average flight time from San Diego Airport to Lambert-St. Louis Intl. Airport (STL) is 5 hours and 36 minutes. Watch a few TV episodes, finish that book … You'll have enough time to sit back and relax.
What airlines have the most flights from San Diego Airport to St. Louis Lambert International Airport?
Southwest Airlines is your ticket to an unforgettable vacation. This renowned carrier has 89 monthly flights between SAN and St. Louis Lambert International Airport.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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