Cheap flights from LGA to FLO (LaGuardia to Florence Regional)

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Cheap Flights from LGA to FLO starting at One Way, $387 Round Trip

Prices starting at $387 for return flights and for one-way flights to Florence Regional were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Aug 29 - Mon, Sep 1
LGA
New York
FLO
Florence
$387 Roundtrip, found 6 hours ago
$387
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Fri, Aug 29 from New York to Florence, returning Mon, Sep 1, priced at $387 found 6 hours ago
Fri, Aug 29 - Mon, Sep 1
LGA
New York
FLO
Florence
$401 Roundtrip, found 6 hours ago
$401
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Fri, Aug 29 from New York to Florence, returning Mon, Sep 1, priced at $401 found 6 hours ago
Fri, Aug 29 - Mon, Sep 1
LGA
New York
FLO
Florence
$439 Roundtrip, found 6 hours ago
$439
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Fri, Aug 29 from New York to Florence, returning Mon, Sep 1, priced at $439 found 6 hours ago
Fri, Aug 29 - Mon, Sep 1
LGA
New York
FLO
Florence
$453 Roundtrip, found 6 hours ago
$453
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Fri, Aug 29 from New York to Florence, returning Mon, Sep 1, priced at $453 found 6 hours ago
Fri, Aug 29 - Mon, Sep 1
LGA
New York
FLO
Florence
$457 Roundtrip, found 6 hours ago
$457
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Fri, Aug 29 from New York to Florence, returning Mon, Sep 1, priced at $457 found 6 hours ago
Fri, Aug 29 - Mon, Sep 1
LGA
New York
FLO
Florence
$501 Roundtrip, found 6 hours ago
$501
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Fri, Aug 29 from New York to Florence, returning Mon, Sep 1, priced at $501 found 6 hours ago
Fri, Aug 29 - Mon, Sep 1
LGA
New York
FLO
Florence
$509 Roundtrip, found 6 hours ago
$509
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Fri, Aug 29 from New York to Florence, returning Mon, Sep 1, priced at $509 found 6 hours ago
Fri, Aug 29 - Mon, Sep 1
LGA
New York
FLO
Florence
$527 Roundtrip, found 6 hours ago
$527
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Fri, Aug 29 from New York to Florence, returning Mon, Sep 1, priced at $527 found 6 hours ago
Fri, Aug 29 - Mon, Sep 1
LGA
New York
FLO
Florence
$552 Roundtrip, found 6 hours ago
$552
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Fri, Aug 29 from New York to Florence, returning Mon, Sep 1, priced at $552 found 6 hours ago
Fri, Aug 29 - Mon, Sep 1
LGA
New York
FLO
Florence
$553 Roundtrip, found 6 hours ago
$553
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Fri, Aug 29 from New York to Florence, returning Mon, Sep 1, priced at $553 found 6 hours ago

Hotel Ideas near Florence Regional

Airport Hotels near Florence Regional

Hyatt Place Florence Downtown
Hyatt Place Florence Downtown
3 out of 5
100 East Evans Street Florence, Florence, SC
Stay at this 3-star business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,000 reviews)
"The Florence Hyatt was extremely clean and well staffed. And my bed was very comfortable."

Reviewed on Jun 8, 2025

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Hyatt Place Florence Downtown
Charming 3-bedroom house with AC, WiFi in lovely Florence
Charming 3-bedroom house with AC, WiFi in lovely Florence
Florence
Stay at this vacation home in Florence. Enjoy laundry facilities and air conditioning. Popular attractions Drs Bruce and Lee Foundation Library and Florence ...
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Charming 3-bedroom house with AC, WiFi in lovely Florence
Charming 3-bedroom home in Florence nea downtown, McLeod and MUSC hospitals.
Charming 3-bedroom home in Florence nea downtown, McLeod and MUSC hospitals.
Florence
Stay at this vacation home in Florence. Enjoy free WiFi, laundry facilities, and patios. Popular attractions Drs Bruce and Lee Foundation Library and Florence ...
Clean, easy stay in Florence
"Our host David is wonderful and he accommodated us over the holidays with some short notice. The property is very clean and well kept. Check in and out was easy. There are plenty of towels and the kitchen has everything you’d need for a comfortable stay. I appreciated how easy it was to communicate ..."

Reviewed on Dec 26, 2024

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Charming 3-bedroom home in Florence nea downtown, McLeod and MUSC hospitals.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Florence

Howard Johnson by Wyndham Florence
Howard Johnson by Wyndham Florence
2 out of 5
2038 W Lucas Street, I-95 Exit 164, Florence, SC
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,216 reviews)
"Everything was excellent!!! The price was excellent too!!!!"

Reviewed on Jun 10, 2025

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Howard Johnson by Wyndham Florence
Park Inn by Radisson Florence, SC
Park Inn by Radisson Florence, SC
2.5 out of 5
1729 Mandeville Road, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,067 reviews)
"The gentleman who checked us in was outstanding. Very friendly and personable"

Reviewed on Jun 10, 2025

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Park Inn by Radisson Florence, SC
Quality Inn & Suites Florence Civic Center
Quality Inn & Suites Florence Civic Center
2.5 out of 5
150 Dunbarton Dr, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,220 reviews)
"Everything was excellent. There was nothing bad about the property. The staff was excellent."

Reviewed on Jun 9, 2025

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Quality Inn & Suites Florence Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Florence Hotels

Red Roof Inn Florence - Civic Center
Red Roof Inn Florence - Civic Center
2 out of 5
2690 David H McLeod Boulevard, Florence, SC
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
6.6/10 (1,000 reviews)
"The property manager on duty when I arrived was very kind and made the check in process easy. The property was clean and convenient to shopping and dining. The only observation I can make is that the exhaust fan in the bathroom was disconnected, dirty and the cover was only partially attached."

Reviewed on Jun 4, 2025

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Red Roof Inn Florence - Civic Center
Budget Inn Timmonsville
Budget Inn Timmonsville
2 out of 5
2200 Cale Yarborough Highway, Timmonsville, SC
Stay at this motel in Timmonsville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attraction Florence Motor Speedway is located nearby.
7/10 Good! (305 reviews)
"Very clean, updated. Easy check in and out. I will stay there again."

Reviewed on Jun 4, 2025

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Budget Inn Timmonsville
Days Inn by Wyndham Florence Near Civic Center
Days Inn by Wyndham Florence Near Civic Center
2.5 out of 5
140 Dunbarton Dr, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.6/10 (1,001 reviews)
"Good quality hotel with affordable pricing."

Reviewed on Jun 11, 2025

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Days Inn by Wyndham Florence Near Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Florence

Home2 Suites by Hilton Florence, SC
Home2 Suites by Hilton Florence, SC
3 out of 5
900 Woody Jones Blvd, Florence, SC
Stay at this 3-star business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,003 reviews)
"Property was nice!! Would definitely recommend and stay again in the future"

Reviewed on Jun 10, 2025

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Home2 Suites by Hilton Florence, SC
Baymont Inn & Suites Florence by Wyndham
Baymont Inn & Suites Florence by Wyndham
2.5 out of 5
1826 W Lucas Street, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Dr. Eddie Floyd Tennis Center ...
"Still in Renovation mode"

Reviewed on Sep 3, 2024

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Baymont Inn & Suites Florence by Wyndham
Country Inn & Suites by Radisson, Florence, SC
Country Inn & Suites by Radisson, Florence, SC
2.5 out of 5
1739 Mandeville Rd, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.4/10 Good! (1,000 reviews)
"A nice overnight stay."

Reviewed on Jun 1, 2025

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Country Inn & Suites by Radisson, Florence, SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

LGA to FLO Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date

Frequently asked questions

What is the shortest flight from LaGuardia Airport (LGA) to Florence Regional Airport?
The quickest flight from LaGuardia Airport (LGA) to FLO is 3 hours and 1 minute. Grab your favorite tipple from the drink cart, get stuck into your travel journal or read a few magazines — you’ll have plenty of time on this medium-haul journey.
How many hours flight from LaGuardia Airport (LGA) to FLO?
The journey from LaGuardia Airport (LGA) to FLO takes an average of 3 hours and 18 minutes. A few good movies, a gripping novel and a decent snooze will help make time fly by.
What airlines have the most flights from LaGuardia Airport to FLO?
You won’t find any airlines that fly direct between LaGuardia Airport (LGA) and FLO. Be organized and secure a multi-stop or one-stop plane ticket.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.