Cheap flights from CYS to RSW (Cheyenne Regional to Southwest Florida Intl.)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Cheap Flights from CYS to RSW starting at One Way, $475 Round Trip

Prices starting at $475 for return flights and for one-way flights to Southwest Florida Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Hotel Ideas near Southwest Florida Intl.

Airport Hotels near Southwest Florida Intl.

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

2 out of 5
10150 Daniels Pkwy Fort Myers FL
$99 nightly
The price is $110 total per night from Feb 1 to Feb 2
$110 total
Feb 1 - Feb 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the clean rooms ...
8/10 Very Good! (1,553 reviews)
The room was clean. The bed was nicely made but not particularly comfortable (kind of stiff).

Reviewed on Jan 28, 2026

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
Holiday Inn Express & Suites Fort Myers Airport by IHG

Holiday Inn Express & Suites Fort Myers Airport by IHG

2.5 out of 5
14567 GLOBAL PARKWAY Fort Myers FL
$182 nightly
The price is $203 total per night from Feb 4 to Feb 5
$203 total
Feb 4 - Feb 5
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (1,006 reviews)
Courteous front staff. We arrived late and asked about a shuttle. They said the driver had to leave but they ordered an Uber for us

Reviewed on Jan 25, 2026

Holiday Inn Express & Suites Fort Myers Airport by IHG
Comfort Inn & Suites Fort Myers Airport

Comfort Inn & Suites Fort Myers Airport

2.5 out of 5
Fort Myers FL
$113 nightly
The price is $126 total per night from Feb 1 to Feb 2
$126 total
Feb 1 - Feb 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,121 reviews)
I watched Karissa at the front desk handle a very difficult guest very well, she didn’t get rattled at all! Please recognize her!

Reviewed on Jan 25, 2026

Comfort Inn & Suites Fort Myers Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Fort Myers

Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

4 out of 5
17260 Harbour Pointe Dr Fort Myers FL
$421 nightly
The price is $470 total per night from Feb 1 to Feb 2
$470 total
Feb 1 - Feb 2
Total with taxes and fees
Book a stay at this spa resort in Fort Myers. Enjoy 3 outdoor pools, a full-service spa, and 4 restaurants. Our guests praise the helpful staff and the property ...
8.4/10 Very Good! (1,004 reviews)
Resort was very nice. Gym needs more cleaning. Bar staff very gracious. Front desk staff courteous. Valet-all staff outstanding!!

Reviewed on Jan 25, 2026

Marriott Sanibel Harbour Resort & Spa
Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers

3 out of 5
12600 University Dr Fort Myers FL
$189 nightly
The price is $211 total per night from Jan 31 to Feb 1
$211 total
Jan 31 - Feb 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.6/10 Excellent! (1,009 reviews)
Clean room helpful staff

Reviewed on Jan 26, 2026

Hilton Garden Inn Ft Myers
Baymont by Wyndham Fort Myers Central

Baymont by Wyndham Fort Myers Central

2.5 out of 5
4850 S Cleveland Ave Fort Myers FL
$90 nightly
The price is $100 total per night from Jan 31 to Feb 1
$100 total
Jan 31 - Feb 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.6/10 (1,004 reviews)
Gray service

Reviewed on Jan 25, 2026

Baymont by Wyndham Fort Myers Central
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Fort Myers Hotels With Airport Transportation

Crowne Plaza Ft. Myers Gulf Coast by IHG

Crowne Plaza Ft. Myers Gulf Coast by IHG

4 out of 5
9931 Interstate Commerce Dr Fort Myers FL
$264 nightly
The price is $294 total per night from Feb 2 to Feb 3
$294 total
Feb 2 - Feb 3
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
9/10 Wonderful! (1,000 reviews)
Beautiful hotel close to the airport. Staff was very friendly and food was great!

Reviewed on Jan 26, 2026

Crowne Plaza Ft. Myers Gulf Coast by IHG
Travelodge by Wyndham Fort Myers Airport

Travelodge by Wyndham Fort Myers Airport

2 out of 5
13661 Indian Paint Lane Fort Myers FL
$69 nightly
The price is $77 total per night from Feb 1 to Feb 2
$77 total
Feb 1 - Feb 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the ...
7.4/10 Good! (1,000 reviews)
Na

Reviewed on Jan 27, 2026

Travelodge by Wyndham Fort Myers Airport
Baymont by Wyndham Fort Myers Airport

Baymont by Wyndham Fort Myers Airport

2.5 out of 5
9401 Marketplace Road Fort Myers FL
$82 nightly
The price is $91 total per night from Feb 4 to Feb 5
$91 total
Feb 4 - Feb 5
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6/10 (1,006 reviews)
Staff and hotel were very clean

Reviewed on Jan 17, 2026

Baymont by Wyndham Fort Myers Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Fort Myers Hotels

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

2 out of 5
10150 Daniels Pkwy Fort Myers FL
$99 nightly
The price is $110 total per night from Feb 1 to Feb 2
$110 total
Feb 1 - Feb 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the clean rooms ...
8/10 Very Good! (1,553 reviews)
The room was clean. The bed was nicely made but not particularly comfortable (kind of stiff).

Reviewed on Jan 28, 2026

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
Travelodge by Wyndham Fort Myers North

Travelodge by Wyndham Fort Myers North

2 out of 5
13353 N Cleveland Ave North Fort Myers FL
$77 nightly
The price is $85 total per night from Feb 8 to Feb 9
$85 total
Feb 8 - Feb 9
Total with taxes and fees
Stay at this hotel in North Fort Myers. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Edison Mall and Centennial Park are located ...
5.8/10 (1,003 reviews)
Very good value - clean rooms - comfortable beds, very good wi-fi, lots of TV options - outsides of building getting a refurbish - not a resort, but a very good value for a budget hotel / motel - WILL STAY THERE AGAIN

Reviewed on Jan 15, 2026

Travelodge by Wyndham Fort Myers North
Baymont by Wyndham Fort Myers Airport

Baymont by Wyndham Fort Myers Airport

2.5 out of 5
9401 Marketplace Road Fort Myers FL
$82 nightly
The price is $91 total per night from Feb 4 to Feb 5
$91 total
Feb 4 - Feb 5
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6/10 (1,006 reviews)
Staff and hotel were very clean

Reviewed on Jan 17, 2026

Baymont by Wyndham Fort Myers Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Fort Myers

Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina

4 out of 5
275 Estero Blvd Fort Myers Beach FL
$390 nightly
The price is $435 total per night from Jan 31 to Feb 1
$435 total
Jan 31 - Feb 1
Total with taxes and fees
Book a stay at this beach resort in Fort Myers Beach. Enjoy free breakfast, 3 outdoor pools, and 3 restaurants. Our guests praise the breakfast and the pool ...
9.4/10 Exceptional! (1,249 reviews)
Excellent as always. Great staff, very friendly and helpful. Great food. Great view.

Reviewed on Jan 27, 2026

Pink Shell Beach Resort and Marina
Sundial Beach Resort & Spa

Sundial Beach Resort & Spa

5 out of 5
1451 Middle Gulf Drive Sanibel FL
$434 nightly
The price is $484 total per night from Feb 1 to Feb 2
$484 total
Feb 1 - Feb 2
Total with taxes and fees
Book a stay at this luxury condo in Sanibel. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the property condition in our reviews. Popular ...
8.6/10 Excellent! (2,592 reviews)
Room was clean and was cleaned in the middle of our stay and staff was great.

Reviewed on Jan 23, 2026

Sundial Beach Resort & Spa
South Seas Resort

South Seas Resort

3.5 out of 5
5400 South Seas Plantation Rd Captiva FL
$568 nightly
The price is $634 total per night from Feb 4 to Feb 5
$634 total
Feb 4 - Feb 5
Total with taxes and fees
Book a stay at this beach resort in Captiva. Enjoy 3 outdoor pools, 7 restaurants, and a private beach. Popular attractions Jungle Drums and McCarthy's Marina ...
8.2/10 Very Good! (1,004 reviews)

Families like: Outdoor pools, waterslide, kitchen, on the beach

Travelers say...
Fantastic place for perfect relaxation, hammocks are placed perfectly for a tropical feel staff is outstanding customer service. A top of the cap to Jeff and Anthony at the front desk.

Reviewed on Dec 10, 2025

South Seas Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

CYS to RSW Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date

Frequently asked questions

What is the shortest flight from Jerry Olson Field to RSW?
Use the opportunity to sit back and chill out on the flight from Cheyenne to Fort Myers. The quickest flight time from Jerry Olson Field to Southwest Florida Intl. Airport (RSW) is 4 hours and 34 minutes, which gives you loads of time to indulge in a drink or get absorbed in a good book.
How many hours flight from Cheyenne Regional Airport (CYS) to Southwest Florida Intl. Airport (RSW)?
From CYS to RSW, you'll be cruising the skies for roughly 4 hours and 34 minutes. Settle back, grab a wine and take out your noise-canceling headphones. It's time to rewatch your favorite TV shows.
What airlines have the most flights from Jerry Olson Field to RSW?
If you're hoping to book with an airline that advertises direct flights from Cheyenne Regional Airport (CYS) to Southwest Florida Intl. Airport (RSW), it's not going to happen. You'll need to make at least one stop to get to Fort Myers.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.