Cheap flights from COU to GSP (Columbia Regional to Greenville-Spartanburg Intl.)

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Cheap Flights from COU to GSP starting at $285 One Way, Round Trip

Prices starting at for return flights and $285 for one-way flights to Greenville-Spartanburg Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Hotel Ideas near Greenville-Spartanburg Intl.

Airport Hotels near Greenville-Spartanburg Intl.

Hampton Inn & Suites Greenville Airport, SC

Hampton Inn & Suites Greenville Airport, SC

2.5 out of 5
128 The Parkway Greenville SC
The price is $101 total per night from Mar 1 to Mar 2
$101 total
per night
Mar 1 - Mar 2
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,009 reviews)
The front desk staff at check in and check out were fantastic!

Reviewed on Feb 15, 2026

Hampton Inn & Suites Greenville Airport, SC
Holiday Inn Express & Suites Greenville Airport by IHG

Holiday Inn Express & Suites Greenville Airport by IHG

3.5 out of 5
2681 Dry Pocket Road Greer SC
The price is $116 total per night from Feb 22 to Feb 23
$116 total
per night
Feb 22 - Feb 23
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (828 reviews)
Friendly staff. Great breakfast. Convenient location.

Reviewed on Feb 16, 2026

Holiday Inn Express & Suites Greenville Airport by IHG
Greenville Marriott

Greenville Marriott

4 out of 5
One Parkway E Greenville SC
The price is $125 total per night from Feb 28 to Mar 1
$125 total
per night
Feb 28 - Mar 1
Book a stay at this business-friendly hotel in Greenville. Enjoy free parking, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.6/10 Excellent! (625 reviews)
Clean rooms and staff is friendly

Reviewed on Feb 16, 2026

Greenville Marriott
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Greenville

Holiday Inn Express & Suites Greenville Airport by IHG

Holiday Inn Express & Suites Greenville Airport by IHG

3.5 out of 5
2681 Dry Pocket Road Greer SC
The price is $116 total per night from Feb 22 to Feb 23
$116 total
per night
Feb 22 - Feb 23
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (828 reviews)
Friendly staff. Great breakfast. Convenient location.

Reviewed on Feb 16, 2026

Holiday Inn Express & Suites Greenville Airport by IHG
Courtyard Greenville-Spartanburg by Marriott

Courtyard Greenville-Spartanburg by Marriott

3 out of 5
115 The Pkwy Greer SC
The price is $129 total per night from Feb 22 to Feb 23
$129 total
per night
Feb 22 - Feb 23
Book a stay at this business-friendly hotel in Greer. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (641 reviews)
Wonderful stay!

Reviewed on Feb 5, 2026

Courtyard Greenville-Spartanburg by Marriott
Comfort Inn & Suites Greer - Greenville

Comfort Inn & Suites Greer - Greenville

2.5 out of 5
1315 W Wade Hampton Blvd Greer SC
The price is $120 total per night from Mar 8 to Mar 9
$120 total
per night
Mar 8 - Mar 9
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (758 reviews)
Room was excellent and front desk was so sweet!

Reviewed on Feb 12, 2026

Comfort Inn & Suites Greer - Greenville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Greenville Hotels With Airport Transportation

Holiday Inn Express & Suites Greenville Airport by IHG

Holiday Inn Express & Suites Greenville Airport by IHG

3.5 out of 5
2681 Dry Pocket Road Greer SC
The price is $116 total per night from Feb 22 to Feb 23
$116 total
per night
Feb 22 - Feb 23
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (828 reviews)
Friendly staff. Great breakfast. Convenient location.

Reviewed on Feb 16, 2026

Holiday Inn Express & Suites Greenville Airport by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Greenville

Comfort Inn & Suites Greer - Greenville

Comfort Inn & Suites Greer - Greenville

2.5 out of 5
1315 W Wade Hampton Blvd Greer SC
The price is $120 total per night from Mar 8 to Mar 9
$120 total
per night
Mar 8 - Mar 9
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (758 reviews)
Room was excellent and front desk was so sweet!

Reviewed on Feb 12, 2026

Comfort Inn & Suites Greer - Greenville
Holiday Inn Express & Suites Greenville Airport by IHG

Holiday Inn Express & Suites Greenville Airport by IHG

3.5 out of 5
2681 Dry Pocket Road Greer SC
The price is $116 total per night from Feb 22 to Feb 23
$116 total
per night
Feb 22 - Feb 23
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (828 reviews)
Friendly staff. Great breakfast. Convenient location.

Reviewed on Feb 16, 2026

Holiday Inn Express & Suites Greenville Airport by IHG
Quality Inn Greer - Greenville

Quality Inn Greer - Greenville

2.5 out of 5
611 W Wade Hampton Blvd Greer SC
The price is $86 total per night from Feb 24 to Feb 25
$86 total
per night
Feb 24 - Feb 25
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
6.8/10 (335 reviews)
The room was acceptable once I found it. Was informed thus hotel was a lobby entrance are I was arriving late and being alone I wanted to walk through a lobby to get to my room. Once arriving, I gave the desk Clerk my reservation information from hotels.com. She could not find it on the computer. ...

Reviewed on Feb 16, 2026

Quality Inn Greer - Greenville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

COU to GSP Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
COU Address & GPS
Address:
Route 1
Columbia MO, 65201
United States
IATA Code:
COU
Longitude:
-92.219167
Latitude:
38.813611
Time Zone:
America/Chicago
GSP Address & GPS
Address:
2000 GPS Drive, Suite 1
Greenville SC, 29651-9202
United States
IATA Code:
GSP
Longitude:
-82.217053
Latitude:
34.890569
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from Columbia Regional Airport to Greenville-Spartanburg Intl. Airport (GSP)?
Traveling from Columbia Regional Airport (COU) to Greenville-Spartanburg Intl. Airport (GSP)? Breaking up the trip is the only option you've got as there are no airlines that service this route directly. However, American Airlines, Qatar Airways and Qantas offer the closest thing — a flight with just one stop.
What is the shortest flight from Columbia Regional Airport (COU) to GSP?
Getting from Columbia Regional Airport to Roger Milliken Field takes at least 3 hours and 43 minutes. Enjoy a wine and watch a show or two — this is the perfect opportunity to chill out.
How many hours flight from Columbia Regional Airport to GSP?
From COU to GSP, you'll be cruising the skies for around 3 hours and 49 minutes. Settle back, order a wine and take out your noise-canceling headphones. It's time to binge-watch your favorite TV shows.
What airlines have the most flights from COU to Greenville-Spartanburg Intl. Airport (GSP)?
Currently, there are no airlines that operate direct flights from Columbia Regional Airport (COU) to Roger Milliken Field. But never fear. There are loads of single or multi-stop options available.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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