$149 Cheap flight deals from Syracuse (SYR) to Santo Domingo (SDQ)

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This Weekend's Flight Deals from Syracuse to Santo Domingo

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Oct 17 - Sun, Oct 25
ITH
Tompkins Regional
SDQ
Las Americas Intl.
$766 Roundtrip, found 23 hours ago
$766
Roundtrip
found 23 hours ago
Select Delta flight, departing Sat, Oct 17 from Tompkins Regional to Las Americas Intl., returning Sun, Oct 25, priced at $766 found 23 hours ago

Airfares from $149 One Way, $379 Round Trip from Syracuse to Santo Domingo

Prices starting at $379 for return flights and $149 for one-way flights to Santo Domingo were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Nov 1 - Thu, Nov 5
SYR
Syracuse
SDQ
Santo Domingo
$379 Roundtrip, found 2 days ago
$379
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sun, Nov 1 from Syracuse to Santo Domingo, returning Thu, Nov 5, priced at $379 found 2 days ago
Sun, Nov 1 - Thu, Nov 5
SYR
Syracuse
SDQ
Santo Domingo
$381 Roundtrip, found 2 days ago
$381
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sun, Nov 1 from Syracuse to Santo Domingo, returning Thu, Nov 5, priced at $381 found 2 days ago
Sun, Nov 1 - Thu, Nov 5
SYR
Syracuse
SDQ
Santo Domingo
$385 Roundtrip, found 2 days ago
$385
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sun, Nov 1 from Syracuse to Santo Domingo, returning Thu, Nov 5, priced at $385 found 2 days ago
Sun, Nov 1 - Thu, Nov 5
SYR
Syracuse
SDQ
Santo Domingo
$387 Roundtrip, found 2 days ago
$387
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sun, Nov 1 from Syracuse to Santo Domingo, returning Thu, Nov 5, priced at $387 found 2 days ago
Tue, Oct 27 - Tue, Nov 3
SYR
Syracuse
SDQ
Santo Domingo
$397 Roundtrip, found 4 days ago
$397
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Oct 27 from Syracuse to Santo Domingo, returning Tue, Nov 3, priced at $397 found 4 days ago

Santo Domingo economy flight packages

Price found within the past 48 hours. Click for updated prices.
Bahia Principe Explore La Romana - Hyatt Inclusive Collection - All Inclusive
4.5-star property

Bahia Principe Explore La Romana - Hyatt Inclusive Collection - All Inclusive

8.6/10 Excellent! (2,628 reviews)

Dec 2 - Dec 7

5 night stay

Syracuse (SYR) to Santo Domingo (SDQ)

American Airlines • Non-stop roundtrip • Coach
Price was $1,728, price is now $1,145 per person
$1,145
per person
found 1 day ago
El personal muy amable, Mary en el bar de la playa “Los Cocos” muy servicial, igual en el restaurant buffet y los restaurantes a la carta Joseun muchacho muy cortes y sencillo. En general todo muy bien Luis del equipo de entretenimiento muy servicial tambien

Reviewed on Oct 9, 2026

Bahia Principe Escape Bouganville - Hyatt Inclusive Collection - Adults Only - All Inclusive
4.5-star property

Bahia Principe Escape Bouganville - Hyatt Inclusive Collection - Adults Only - All Inclusive

8.8/10 Excellent! (2,571 reviews)

Dec 2 - Dec 7

5 night stay

Syracuse (SYR) to Santo Domingo (SDQ)

American Airlines • Non-stop roundtrip • Coach
Save 100% on your flight
Price was $2,028, price is now $1,288 per person
$1,288
per person
found 1 day ago

Hacienda Samana Bay Hotel & Residence
5.0-star property

Hacienda Samana Bay Hotel & Residence

9.4/10 Exceptional! (422 reviews)

Dec 2 - Dec 7

5 night stay

Syracuse (SYR) to Santo Domingo (SDQ)

American Airlines • Non-stop roundtrip • Coach
Price was $1,447, price is now $1,344 per person
$1,344
per person
found 1 day ago
Excelente

Reviewed on Oct 8, 2026

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More About Flying To Santo Domingo from Syracuse

Route Information for Flights from Syracuse to Santo Domingo

Origin Airport IATA Code
SYR
Destination Airport IATA Code
SDQ
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Syracuse to Santo Domingo

Orbitz combines guaranteed low prices with cutting-edge mobile tools for travel from Syracuse to Santo Domingo to give you a travel experience that is second to none.

Bargain Travel at Your Fingertips

Orbitz provides the cheapest fares from Syracuse to Santo Domingo. When reserving your flight you can mix and match a range of low cost airlines for you departing and returning domestic or international flights. This way you can travel on a budget while selecting the flights that suit your schedule.

Modern Tools for Fast-Paced Travel

Orbitz makes use of the latest technology to ensure that you are always kept up-to-date on the status of your Syracuse to Santo Domingo flights. Through easy-to-use mobile Android and iPhone apps you can book low cost flights from Syracuse to Santo Domingo and choose a range of cheap hotels to stay in.

Enjoy Stress-Free Travel with Flight Alerts

Once you have booked your flights from Syracuse to Santo Domingo on Orbitz you will always be kept informed of any changes to your flight. When you opt into Orbitz’s free email and SMS alerts on your Syracuse to Santo Domingo flights you can ask Orbitz to send the flight details to up to 6 other contacts, so keeping your family and business team informed is a cinch.

Frequent Flyer Program

For loyal Orbitz customers who fly from Syracuse to Santo Domingo the chance to join our frequent flyer program is an added bonus. Simply log-on to your online account and input your frequent flyer number for future flights.

Frequently asked questions

What is the shortest flight from Syracuse to Santo Domingo?
Jetting from Syracuse Hancock Intl. Airport to Las Americas Intl. Airport (SDQ) will take you at least 4 hours and 51 minutes. Savor a wine and read a few magazines — here's your chance to sit back and relax.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.