$269 Cheap flight deals from Indianapolis (IND) to San Francisco (PVR)

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Airfares from $269 One Way, $573 Round Trip from Indianapolis to San Francisco

Prices starting at $573 for return flights and $269 for one-way flights to San Francisco were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Nov 12 - Fri, Nov 20
IND
Indianapolis
PVR
Puerto Vallarta
$573 Roundtrip, found 7 hours ago
$573
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Thu, Nov 12 from Indianapolis to Puerto Vallarta, returning Fri, Nov 20, priced at $573 found 7 hours ago
Thu, Nov 12 - Fri, Nov 20
IND
Indianapolis
PVR
Puerto Vallarta
$577 Roundtrip, found 7 hours ago
$577
Roundtrip
found 7 hours ago
Select Southwest Airlines flight, departing Thu, Nov 12 from Indianapolis to Puerto Vallarta, returning Fri, Nov 20, priced at $577 found 7 hours ago
Thu, Nov 12 - Fri, Nov 20
IND
Indianapolis
PVR
Puerto Vallarta
$579 Roundtrip, found 7 hours ago
$579
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Thu, Nov 12 from Indianapolis to Puerto Vallarta, returning Fri, Nov 20, priced at $579 found 7 hours ago
Thu, Nov 12 - Fri, Nov 20
IND
Indianapolis
PVR
Puerto Vallarta
$579 Roundtrip, found 7 hours ago
$579
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Thu, Nov 12 from Indianapolis to Puerto Vallarta, returning Fri, Nov 20, priced at $579 found 7 hours ago
Sun, Feb 21 - Thu, Mar 4
IND
Indianapolis
PVR
Puerto Vallarta
$581 Roundtrip, found 3 days ago
$581
Roundtrip
found 3 days ago
Select Aeromexico flight, departing Sun, Feb 21 from Indianapolis to Puerto Vallarta, returning Thu, Mar 4, priced at $581 found 3 days ago

San Francisco economy flight packages

Price found within the past 48 hours. Click for updated prices.
Garza Blanca Preserve Resort & Spa - All Inclusive
5.0-star property

Garza Blanca Preserve Resort & Spa - All Inclusive

9.2/10 Wonderful! (791 reviews)

Oct 25 - Oct 30

5 night stay

Indianapolis (IND) to Puerto Vallarta (PVR)

American Airlines • Non-stop roundtrip • Coach
Save 100% on your flight
Price was $3,095, price is now $1,548 per person
$1,548
per person
found 1 day ago
I love the outdoor pool, staffs very friendly and helpful. No activities at the resort.

Reviewed on Sep 11, 2026

Garza Blanca Sanctuary All Inclusive
5.0-star property

Garza Blanca Sanctuary All Inclusive

9.6/10 Exceptional! (18 reviews)

Oct 25 - Oct 30

5 night stay

Indianapolis (IND) to Puerto Vallarta (PVR)

American Airlines • Non-stop roundtrip • Coach
Price was $3,706, price is now $1,839 per person
$1,839
per person
found 1 day ago
My wife and I chose Sanctuary Garza Blanca Puerto Vallarta to celebrate our 16th wedding anniversary, and from the moment we arrived, we knew we were in for something special. We travel frequently and have been fortunate to experience some of the finest luxury hotels around the world, including Four Seasons, Mandarin Oriental, and Raffles. These experiences have given us a deep appreciation for thoughtful design, refined service, exceptional dining, and the small details that make a stay truly memorable. We stayed in the brand-new tower, and the experience was spectacular. Our room was beautifully designed, modern, spacious, and exceptionally comfortable. However, the views were undoubtedly the star of the show. Waking up to the Pacific Ocean each morning was breathtaking, and the scenery from our room and throughout the resort was unforgettable. The infinity pool was another highlight. Its My wife and I chose Sanctuary Garza Blanca Puerto Vallarta to celebrate our 16th wedding anniversary, and from the moment we arrived, we knew we were in for something special. We travel frequently and have been fortunate to experience some of the finest luxury hotels around the world, including Four Seasons, Mandarin Oriental, and Raffles. These experiences have given us a deep appreciation for thoughtful design, refined service, exceptional dining, and the small details that make a stay truly memorable. Sanctuary Garza Blanca not only met our expectations.it exceeded them.

Reviewed on Sep 12, 2026

Hotel Mousai Puerto Vallarta - All Inclusive - Adults Only
5.0-star property

Hotel Mousai Puerto Vallarta - All Inclusive - Adults Only

9/10 Wonderful! (208 reviews)

Oct 25 - Oct 30

5 night stay

Indianapolis (IND) to Puerto Vallarta (PVR)

American Airlines • Non-stop roundtrip • Coach
Save 100% on your flight
Price was $3,388, price is now $1,750 per person
$1,750
per person
found 1 day ago
This was our second time staying here, we had an amazing time the first time & coming back for the second time just proved to us why we decided to come back. Absolutely love it here!

Reviewed on Sep 8, 2026

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More About Flying To San Francisco from Indianapolis

Route Information for Flights from Indianapolis to San Francisco

Origin Airport IATA Code
IND
Destination Airport IATA Code
PVR
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Indianapolis to San Francisco

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.