Business Hotels in Sikeston, MO
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Featured Sikeston Business Hotels

Pear Tree Inn Sikeston
2602 E Malone Avenue, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
$80 nightly
The price is $92 total per night
$92 total
Aug 13 - Aug 14
Total includes taxes and fees
Pear Tree Inn Sikeston features an indoor pool, an outdoor pool, and a gym. The front desk is staffed 24 hours a day to help with securing valuables and dry cleaning/laundry. Additional amenities include free WiFi in public areas, a hot tub, and a business center.
Pool
Hot Tub

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street, Cape Girardeau, MO
Free Cancellation
$103 nightly
The price is $116 total per night
$116 total
Aug 17 - Aug 18
Total includes taxes and fees
At Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, guests enjoy a full-service spa, an indoor pool, and a gym. If you plan to drive, free parking is available. The front desk is staffed 24/7 to help with dry cleaning/laundry, luggage storage, and securing valuables. Other amenities at this spa hotel include free WiFi in public areas, conference space, and a business center.
Pool
Breakfast included

Drury Inn & Suites Jackson MO
225 Drury Lane, Jackson, MO
Free Cancellation
Reserve now, pay when you stay
$90 nightly
The price is $95 total per night
$95 total
Aug 12 - Aug 13
Total includes taxes and fees
Guests of Drury Inn & Suites Jackson MO have access to an indoor pool, a gym, and free WiFi in public areas. There's free parking if you drive. The 24-hour front desk has staff standing by to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a hot tub, meeting rooms, and a business center.
Pool
Hot Tub

Best Western Plus Sikeston
120 S Interstate Drive, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
$88 nightly
The price is $100 total per night
$100 total
Aug 17 - Aug 18
Total includes taxes and fees
Guests of Best Western Plus Sikeston have access to an indoor pool, a gym, and free WiFi in public areas. If you plan to drive, free parking is available. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a 24-hour business center, a computer station, and express check-out.
Pool
Breakfast included

Drury Inn & Suites Cape Girardeau
3303 Campster Drive, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
$90 nightly
The price is $102 total per night
$102 total
Aug 17 - Aug 18
Total includes taxes and fees
Guests of Drury Inn & Suites Cape Girardeau have access to an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The 24-hour front desk has staff standing by to help with luggage storage and securing valuables. Additional amenities include a hot tub, meeting rooms, and a business center.
Pool
Hot Tub

Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
$70 nightly
The price is $79 total per night
$79 total
Aug 10 - Aug 11
Total includes taxes and fees
Guests of Pear Tree Inn Cape Girardeau West enjoy a gym, free WiFi in public areas, and a 24-hour business center. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. This smoke-free hotel also has a TV in a common area.
Breakfast included
Pet friendly

Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
$71 nightly
The price is $81 total per night
$81 total
Aug 17 - Aug 18
Total includes taxes and fees
Renovated in 2023, Days Inn and Suites by Wyndham Sikeston offers a gym, free WiFi in public areas, and meeting rooms. Free parking is included with your stay. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a library, laundry facilities, and a banquet hall.
Breakfast included
Pet friendly

Holiday Inn Express & Suites Sikeston Southwest by IHG
115 Hospitality Dr, Sikeston, MO
Free Cancellation
$101 nightly
The price is $114 total per night
$114 total
Sep 5 - Sep 6
Total includes taxes and fees
Guests staying at Holiday Inn Express & Suites Sikeston Southwest by IHG enjoy an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The 24-hour front desk has staff standing by to help with securing valuables and luggage storage. Additional amenities include a business center, coffee/tea in a common area, and a meeting room.
Pool
Breakfast included

Comfort Suites Jackson-Cape Girardeau
2904 Old Orchard Rd, Jackson, MO
Free Cancellation
Reserve now, pay when you stay
$89 nightly
The price is $96 total per night
$96 total
Sep 1 - Sep 2
Total includes taxes and fees
At Comfort Suites Jackson-Cape Girardeau, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. If you decide to drive, there's free parking. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Additional amenities include conference space, a 24-hour business center, and a computer station.
Pool
Breakfast included

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
$90 nightly
The price is $103 total per night
$103 total
Aug 17 - Aug 18
Total includes taxes and fees
Drury Inn & Suites Sikeston, MO features an indoor pool, an outdoor pool, and a gym. If you drive, put free parking to good use. The front desk is staffed 24/7 to help with securing valuables, dry cleaning/laundry, and luggage storage. Additional amenities include free WiFi in public areas, meeting rooms, and a business center.
Pool
Breakfast included

Quality Inn
2011 North Kingshighway, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
$60 nightly
The price is $68 total per night
$68 total
Aug 14 - Aug 15
Total includes taxes and fees
Guests of Quality Inn enjoy features like an outdoor pool, free WiFi in public areas, and a computer station. If you decide to drive, there's free parking. The 24-hour front desk has staff always at the ready. Additional amenities include laundry facilities, a TV in a common area, and a vending machine.
Pool
Breakfast included

Candlewood Suites Cape Girardeau by IHG
485 S Mount Auburn Rd, Cape Girardeau, MO
Free Cancellation
$78 nightly
The price is $93 total per night
$93 total
Aug 17 - Aug 18
Total includes taxes and fees
At Candlewood Suites Cape Girardeau by IHG, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. If you drive, take advantage of free parking. The front desk is staffed 24 hours a day to help with securing valuables and dry cleaning/laundry. Additional amenities include meeting rooms, a business center, and free newspapers.
Pool
Pet friendly

Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
$102 nightly
The price is $115 total per night
$115 total
Aug 14 - Aug 15
Total includes taxes and fees
At Drury Plaza Hotel Cape Girardeau Conference Center, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a hot tub, meeting rooms, and a conference center.
Pool
Hot Tub

Hampton Inn Cape Girardeau I 55 East
207 S Mt Auburn Rd, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
$110 nightly
The price is $124 total per night
$124 total
Aug 17 - Aug 18
Total includes taxes and fees
At Hampton Inn Cape Girardeau I 55 East, guests enjoy an indoor pool, a gym, and free WiFi in public areas. If you decide to drive, there's free parking. The front desk is staffed 24/7 to help with luggage storage, dry cleaning/laundry, and securing valuables. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include a business center, coffee/tea in a common area, and a meeting room.
Pool
Breakfast included

Travelodge by Wyndham Dexter
1608 E Business US 60, Dexter, MO
Free Cancellation
Reserve now, pay when you stay
$95 nightly
The price is $107 total per night
$107 total
Aug 10 - Aug 11
Total includes taxes and fees
Travelodge by Wyndham Dexter features free WiFi in public areas, a business center, and coffee in a common area. Free parking is included with your stay. The 24-hour front desk has staff standing by to help with luggage storage and tours/tickets. Additional amenities include a meeting room, laundry facilities, and a vending machine.
Pet friendly
Parking included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Sikeston hotels essential information
Accommodation | 256 hotels |
---|---|
Lowest Price | $68 |
Highest Price | $124 |
Popular hotels | Pear Tree Inn Sikeston, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, Drury Inn & Suites Jackson MO, Best Western Plus Sikeston, Drury Inn & Suites Cape Girardeau, Pear Tree Inn Cape Girardeau West, Days Inn and Suites by Wyndham Sikeston, Holiday Inn Express & Suites Sikeston Southwest by IHG, Comfort Suites Jackson-Cape Girardeau, Drury Inn & Suites Sikeston, MO, Quality Inn, Candlewood Suites Cape Girardeau by IHG, Drury Plaza Hotel Cape Girardeau Conference Center, Hampton Inn Cape Girardeau I 55 East, Travelodge by Wyndham Dexter |
Recent Business Hotels Reviews

Days Inn and Suites by Wyndham Sikeston
5/5 Excellent
"Only thing I didn’t like was that the shower didn’t get hot "
A verified traveler stayed at Days Inn and Suites by Wyndham Sikeston
Posted 4 days ago
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