Cheap flights from SYR to EYW (Hancock Intl. to Key West Intl.)

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Cheap Flights from SYR to EYW starting at $110 One Way, $219 Round Trip

Prices starting at $219 for return flights and $110 for one-way flights to Key West Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Mar 24 - Wed, Apr 8
SYR
Syracuse
EYW
Key West
$219 Roundtrip, found 16 hours ago
$219
Roundtrip
found 16 hours ago
Select Delta flight, departing Tue, Mar 24 from Syracuse to Key West, returning Wed, Apr 8, priced at $219 found 16 hours ago
Tue, Feb 10 - Wed, Feb 11
SYR
Syracuse
EYW
Key West
$219 Roundtrip, found 3 days ago
$219
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Feb 10 from Syracuse to Key West, returning Wed, Feb 11, priced at $219 found 3 days ago
Mon, Feb 9 - Wed, Feb 11
SYR
Syracuse
EYW
Key West
$224 Roundtrip, found 3 days ago
$224
Roundtrip
found 3 days ago
Select Delta flight, departing Mon, Feb 9 from Syracuse to Key West, returning Wed, Feb 11, priced at $224 found 3 days ago
Mon, Feb 9 - Thu, Feb 26
SYR
Syracuse
EYW
Key West
$229 Roundtrip, found 16 hours ago
$229
Roundtrip
found 16 hours ago
Select Delta flight, departing Mon, Feb 9 from Syracuse to Key West, returning Thu, Feb 26, priced at $229 found 16 hours ago
Sun, Feb 22 - Wed, Mar 11
SYR
Syracuse
EYW
Key West
$235 Roundtrip, found 16 hours ago
$235
Roundtrip
found 16 hours ago
Select Delta flight, departing Sun, Feb 22 from Syracuse to Key West, returning Wed, Mar 11, priced at $235 found 16 hours ago

Hotel Ideas near Key West Intl.

Airport Hotels near Key West Intl.

Hyatt Vacation Club at Windward Pointe, Key West

Hyatt Vacation Club at Windward Pointe, Key West

3.5 out of 5
3675 South Roosevelt Boulevard Key West FL
$498 nightly
The price is $560 total per night from Jan 24 to Jan 25
$560 total
Jan 24 - Jan 25
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, free parking, and a snack bar/deli. Our guests praise the pool and the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,011 reviews)
Spacious and comfortable

Reviewed on Jan 4, 2026

Hyatt Vacation Club at Windward Pointe, Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
$389 nightly
The price is $438 total per night from Jan 14 to Jan 15
$438 total
Jan 14 - Jan 15
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,300 reviews)
It was the perfect hotel. There was a shuttle to the airport and to the downtown which we used every day. The rooms were clean. Breakfast was wonderful. The pool area was fantastic. There is a tiki hut bar restaurant that we ate at multiple times. I could not recommend it enough.

Reviewed on Jan 4, 2026

Hampton Inn Key West FL
DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
$298 nightly
The price is $335 total per night from Jan 13 to Jan 14
$335 total
Jan 13 - Jan 14
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8/10 Very Good! (1,022 reviews)
Clean ok Dripping sink in the kitchenette not ok Tiniest balcony ever, eh. Latin

Reviewed on Jan 4, 2026

DoubleTree Resort by Hilton Grand Key - Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Key West

Beachside Resort & Residences

Beachside Resort & Residences

3.5 out of 5
3841 N Roosevelt Blvd Key West FL
$316 nightly
The price is $355 total per night from Jan 11 to Jan 12
$355 total
Jan 11 - Jan 12
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 2 restaurants, and a private beach. Our guests praise the pool and the helpful staff in our reviews. ...
8.6/10 Excellent! (1,879 reviews)
Front desk staff was excellent as was the breakfast staff. Only had breakfast and it was excellent. Room could’ve been cleaner because that was disappointing. Two out of three soaps didn’t work in the shower. Overall a nice stay.

Reviewed on Jan 7, 2026

Beachside Resort & Residences
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
$283 nightly
The price is $318 total per night from Jan 11 to Jan 12
$318 total
Jan 11 - Jan 12
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8/10 Very Good! (1,834 reviews)
Room were cleaned and bathroom. Loved the shuttle transportation. And the amenities. Would stay again

Reviewed on Jan 9, 2026

Blue Flamingo Resort Key West
Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street Key West FL
$435 nightly
The price is $489 total per night from Jan 13 to Jan 14
$489 total
Jan 13 - Jan 14
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.6/10 Excellent! (2,976 reviews)
Great staff, Konstantin, the bartender at the pineapple pool was amazing!

Reviewed on Jan 5, 2026

Southernmost Beach Resort and Guesthouses
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Key West Hotels With Airport Transportation

DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
$298 nightly
The price is $335 total per night from Jan 13 to Jan 14
$335 total
Jan 13 - Jan 14
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8/10 Very Good! (1,022 reviews)
Clean ok Dripping sink in the kitchenette not ok Tiniest balcony ever, eh. Latin

Reviewed on Jan 4, 2026

DoubleTree Resort by Hilton Grand Key - Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
$389 nightly
The price is $438 total per night from Jan 14 to Jan 15
$438 total
Jan 14 - Jan 15
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,300 reviews)
It was the perfect hotel. There was a shuttle to the airport and to the downtown which we used every day. The rooms were clean. Breakfast was wonderful. The pool area was fantastic. There is a tiki hut bar restaurant that we ate at multiple times. I could not recommend it enough.

Reviewed on Jan 4, 2026

Hampton Inn Key West FL
Eden House

Eden House

3.5 out of 5
1015 Fleming St Key West FL
$276 nightly
The price is $311 total per night from Jan 11 to Jan 12
$311 total
Jan 11 - Jan 12
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, in-room massages, and a 24-hour front desk. Our guests praise the pool and the helpful staff in our reviews. ...
9/10 Wonderful! (1,002 reviews)
Any small issues were taken care of quickly.

Reviewed on Jan 5, 2026

Eden House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Key West Hotels

Southwinds Motel

Southwinds Motel

2 out of 5
1321 Simonton Street Key West FL
$233 nightly
The price is $262 total per night from Jan 11 to Jan 12
$262 total
Jan 11 - Jan 12
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,266 reviews)
Check-in staff was kind and friendly. We arrived at the hotel earlier and they accommodated an early check in as there was a room ready.

Reviewed on Jan 8, 2026

Southwinds Motel
Seashell Motel

Seashell Motel

1.5 out of 5
718 South Street Key West FL
$175 nightly
The price is $197 total per night from Jan 11 to Jan 12
$197 total
Jan 11 - Jan 12
Total with taxes and fees
Stay at this hostel in Key West. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7.8/10 Good! (1,003 reviews)
Great

Reviewed on Dec 22, 2025

Seashell Motel
Duval House

Duval House

3 out of 5
815 Duval St Key West FL
$231 nightly
The price is $257 total per night from Jan 14 to Jan 15
$257 total
Jan 14 - Jan 15
Total with taxes and fees
Stay at this B&B in Key West. Enjoy parking (surcharge), daily housekeeping, and a garden. Our guests praise the breakfast and the pool in our reviews. Popular ...
9.4/10 Exceptional! (1,016 reviews)
Staff was beyond courteous and accommodating, thank you!

Reviewed on Jan 5, 2026

Duval House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Key West

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street Key West FL
$435 nightly
The price is $489 total per night from Jan 13 to Jan 14
$489 total
Jan 13 - Jan 14
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.6/10 Excellent! (2,976 reviews)
Great staff, Konstantin, the bartender at the pineapple pool was amazing!

Reviewed on Jan 5, 2026

Southernmost Beach Resort and Guesthouses
Margaritaville Beach House Key West

Margaritaville Beach House Key West

4 out of 5
2001 South Roosevelt Blvd Key West FL
Book a stay at this beach hotel in Key West. Enjoy free parking, 2 restaurants, and breakfast (surcharge). Popular attractions Duval Street and Smathers Beach ...
8.2/10 Very Good! (999 reviews)

Families like: Outdoor pool, babysitting, close to beach, bicycle rentals

Travelers say...
Room was clean and comfortable but after first day towels were shorted. Had to ask for more twice Desk staff were very nice and helpful. Concierge was helpful with rentals Restaurant was not as good as past stays when Sheraton. Food even pancakes were tough and overcooked. Shuttle drivers were very ...

Reviewed on Dec 4, 2025

Get rates
Margaritaville Beach House Key West
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
$283 nightly
The price is $318 total per night from Jan 11 to Jan 12
$318 total
Jan 11 - Jan 12
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8/10 Very Good! (1,834 reviews)

Families like: Outdoor pools, miniature golf, game room, bicycle rentals

Travelers say...
Room were cleaned and bathroom. Loved the shuttle transportation. And the amenities. Would stay again

Reviewed on Jan 9, 2026

Blue Flamingo Resort Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

SYR to EYW Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
SYR Address & GPS
Address:
City Hall
Syracuse NY, 13212
United States
IATA Code:
SYR
Longitude:
-76.112231
Latitude:
43.113984
Time Zone:
America/New_York
EYW Address & GPS
Address:
3491 South Roosevelt Boulevard
Key West FL, 33040-5260
United States
IATA Code:
EYW
Longitude:
-81.75501
Latitude:
24.553574
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from Syracuse Hancock Intl. Airport to Key West Intl. Airport?
Unfortunately, you won't find any direct flights on this route. But American Airlines, United Airlines and Delta Air Lines can get you from Hancock Intl. Airport (SYR) to Key West Intl. Airport (EYW) with only one stopover.
What is the shortest flight from Hancock Intl. Airport (SYR) to Key West Intl. Airport (EYW)?
Use the opportunity to relax on your trip from Syracuse to Key West. The quickest flight time from Hancock Intl. Airport (SYR) to Key West Intl. Airport is 4 hours and 57 minutes, which gives you more than enough time to enjoy a wine or get engrossed in a book.
How many hours flight from Hancock Intl. Airport (SYR) to Key West Intl. Airport?
From SYR to Key West Intl. Airport, you'll be in the sky for roughly 5 hours and 3 minutes. Get comfy, grab a wine and take out your noise-canceling earphones. It's time for a movie marathon.
What airlines have the most flights from Syracuse Hancock Intl. Airport to Key West Intl. Airport?
Right now, no airlines have direct flights between Syracuse Hancock Intl. Airport and Key West Intl. Airport. But don't panic! There are several single or multi-stop options available.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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