Cheap flights from STL to TUP (Lambert-St. Louis Intl. to Tupelo Regional)
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
Hotel Ideas near Tupelo Regional
Airport Hotels near Tupelo Regional
Holiday Inn Hotel & Suites Tupelo North by IHG
923 North Gloster Tupelo MS
$118 nightly
The price is $129 total per night from Jan 11 to Jan 12
$129 total
Jan 11 - Jan 12
Total with taxes and fees
Book a stay at this business-friendly hotel in Tupelo. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,003 reviews)
Yes
Reviewed on Dec 28, 2025
Red Roof Inn Tupelo
1516 Mccullough Blvd Tupelo MS
$62 nightly
The price is $67 total per night from Jan 11 to Jan 12
$67 total
Jan 11 - Jan 12
Total with taxes and fees
Book a stay at this business-friendly hotel in Tupelo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.2/10 Very Good! (1,000 reviews)
I always have a good experience at this hotel. This is very cost-effective for me, especially since I travel with my small dog…Staff is considerate, the room was clean and grounds are well kept.
Reviewed on Dec 28, 2025
La Quinta Inn & Suites by Wyndham Tupelo
1013 N Gloster St Tupelo MS
$88 nightly
The price is $96 total per night from Jan 8 to Jan 9
$96 total
Jan 8 - Jan 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Tupelo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,002 reviews)
Clean and spacious room. Comfy bed. Friendly staff.
Reviewed on Jan 1, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels In Tupelo
Best Western Plus Tupelo Inn & Suites
3158 N Gloster Street Tupelo MS
$97 nightly
The price is $106 total per night from Jan 5 to Jan 6
$106 total
Jan 5 - Jan 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Tupelo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,011 reviews)
The place was very nice. The desk clerk was kind. The only negative was the matress is hard as a rock. An it would be nice if the breakfast would last later.
Reviewed on Jan 2, 2026
Tru By Hilton Tupelo
1003 Landmark Blvd Tupelo MS
$102 nightly
The price is $111 total per night from Jan 10 to Jan 11
$111 total
Jan 10 - Jan 11
Total with taxes and fees
Stay at this hotel in Tupelo. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. ...
9.2/10 Wonderful! (652 reviews)
Front desk was wonderful. Very clean and comfortable
Reviewed on Dec 31, 2025
Holiday Inn Hotel & Suites Tupelo North by IHG
923 North Gloster Tupelo MS
$118 nightly
The price is $129 total per night from Jan 11 to Jan 12
$129 total
Jan 11 - Jan 12
Total with taxes and fees
Book a stay at this business-friendly hotel in Tupelo. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,003 reviews)
Yes
Reviewed on Dec 28, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Tupelo Hotels With Airport Transportation
Candlewood Suites Tupelo North by IHG
979 North Gloster St Street Tupelo MS
$118 nightly
The price is $129 total per night from Jan 11 to Jan 12
$129 total
Jan 11 - Jan 12
Total with taxes and fees
Book a stay at this business-friendly hotel in Tupelo. Enjoy free WiFi, free parking, and a free airport shuttle. Our guests praise the helpful staff in our ...
8.4/10 Very Good! (437 reviews)
The thing wrong was no breakfast included
Reviewed on Nov 21, 2025
Holiday Inn Hotel & Suites Tupelo North by IHG
923 North Gloster Tupelo MS
$118 nightly
The price is $129 total per night from Jan 11 to Jan 12
$129 total
Jan 11 - Jan 12
Total with taxes and fees
Book a stay at this business-friendly hotel in Tupelo. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,003 reviews)
Yes
Reviewed on Dec 28, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Low Priced Tupelo Hotels
Red Roof Inn Tupelo
1516 Mccullough Blvd Tupelo MS
$62 nightly
The price is $67 total per night from Jan 11 to Jan 12
$67 total
Jan 11 - Jan 12
Total with taxes and fees
Book a stay at this business-friendly hotel in Tupelo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.2/10 Very Good! (1,000 reviews)
I always have a good experience at this hotel. This is very cost-effective for me, especially since I travel with my small dog…Staff is considerate, the room was clean and grounds are well kept.
Reviewed on Dec 28, 2025
Baymont by Wyndham Tupelo
625 Spicer Drive Tupelo MS
$58 nightly
The price is $63 total per night from Jan 11 to Jan 12
$63 total
Jan 11 - Jan 12
Total with taxes and fees
Book a stay at this business-friendly motel in Tupelo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.4/10 Good! (1,004 reviews)
Staff was extremely nice,room was good, love the pool, the only issue with trip was my fsult, booked it for the first week that poped up on my calender through app and hit my days but was for following week so when arrived had pay a fee to reschedule date issue although plenty of rooms available ...
Reviewed on Dec 26, 2025
Americas Best Value Inn Tupelo
4701 Leeb Drive Tupelo MS
$54 nightly
The price is $58 total per night from Feb 1 to Feb 2
$58 total
Feb 1 - Feb 2
Total with taxes and fees
Stay at this hotel in Tupelo. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (1,002 reviews)
We weren’t there long. It was perfect for a good get away from town traffic.
Reviewed on Jan 2, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Tupelo
Americas Best Value Inn Tupelo
4701 Leeb Drive Tupelo MS
$54 nightly
The price is $58 total per night from Feb 1 to Feb 2
$58 total
Feb 1 - Feb 2
Total with taxes and fees
Stay at this hotel in Tupelo. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (1,002 reviews)
We weren’t there long. It was perfect for a good get away from town traffic.
Reviewed on Jan 2, 2026
Concord Inn
1102 State HWY 15 North New Albany MS
Stay at this B&B in New Albany. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Shady Dell Park and Bowman Tennis Center are located ...
Ready to go back!
A beautiful place to stay, inside and out. Very relaxing, inviting on the inside and gorgeous, peaceful grounds to stroll around. Tanya couldn’t be a nicer host. We’re already looking forward to our next visit.
Reviewed on Oct 23, 2018
Spark by Hilton Tupelo
186 Stone Creek Blvd Tupelo MS
$73 nightly
The price is $80 total per night from Jan 11 to Jan 12
$80 total
Jan 11 - Jan 12
Total with taxes and fees
Book a stay at this business-friendly hotel in Tupelo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (1,001 reviews)
Great hotel, very comfortable room. But breakfast is very basic.
Reviewed on Jan 1, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
STL to TUP Route Info
Origin Airport | |
|---|---|
Destination Airport | |
Number Of Airlines Serving | |
Distance | |
Shortest Flight Departure Time | |
Shortest Flight Departure Date |
- Airport Locations
- More Popular Flights
- Top Trending
- Flights from Other Cities
- Flights From Other Airports
STL Address & GPS
Address:
10701 Lambert International Blvd.
Saint Louis MO, 63145
United States
IATA Code:
STL
Longitude:
-90.379002
Latitude:
38.748707
Time Zone:
America/Chicago
TUP Address & GPS
Address:
Lemons Drive
Tupelo MS, 38801-7024
United States
IATA Code:
TUP
Longitude:
-88.767222
Latitude:
34.258889
Time Zone:
America/Chicago
Other Flights from Lambert-St. Louis Intl. Airport (STL)
- Abraham Lincoln Capital Airport (SPI)
- Quincy Regional-Baldwin Field Airport (UIN)
- Columbia Regional Airport (COU)
- Williamson County Regional Airport (MWA)
- Decatur Airport (DEC)
- Cape Girardeau Municipal Airport (CGI)
- St. Robert Regional Airport (TBN)
- Cairo Regional Airport (CIR)
- Greater Peoria Regional Airport (PIA)
- Central Illinois Regional Airport (BMI)
Frequently asked questions
Map To Nearby Hotels
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.