$84 Cheap flight deals from Columbia (CAE) to Biloxi (MOB)

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This Weekend's Flight Deals from Columbia to Biloxi

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Aug 30 - Mon, Sep 1
CAE
Columbia Metropolitan
MOB
Mobile Regional
$450 Roundtrip, found 1 day ago
$450
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Aug 30 from Columbia Metropolitan to Mobile Regional, returning Mon, Sep 1, priced at $450 found 1 day ago

Airfares from $84 One Way, $177 Round Trip from Columbia to Biloxi

Prices starting at $177 for return flights and $84 for one-way flights to Biloxi were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Oct 30 - Sun, Nov 2
CAE
Columbia
MSY
New Orleans
$177 Roundtrip, found 1 hour ago
$177
Roundtrip
found 1 hour ago
Select Spirit Airlines flight, departing Thu, Oct 30 from Columbia to New Orleans, returning Sun, Nov 2, priced at $177 found 1 hour ago
Fri, Oct 31 - Sun, Nov 2
CAE
Columbia
MSY
New Orleans
$179 Roundtrip, just found
$179
Roundtrip
just found
Select Spirit Airlines flight, departing Fri, Oct 31 from Columbia to New Orleans, returning Sun, Nov 2, priced at $179 just found
Thu, Oct 23 - Sun, Oct 26
CAE
Columbia
MSY
New Orleans
$185 Roundtrip, found 5 hours ago
$185
Roundtrip
found 5 hours ago
Select Spirit Airlines flight, departing Thu, Oct 23 from Columbia to New Orleans, returning Sun, Oct 26, priced at $185 found 5 hours ago
Thu, Oct 16 - Sun, Oct 19
CAE
Columbia
MSY
New Orleans
$189 Roundtrip, found 6 days ago
$189
Roundtrip
found 6 days ago
Select Spirit Airlines flight, departing Thu, Oct 16 from Columbia to New Orleans, returning Sun, Oct 19, priced at $189 found 6 days ago
Fri, Nov 14 - Mon, Nov 17
CAE
Columbia
MSY
New Orleans
$193 Roundtrip, found 2 days ago
$193
Roundtrip
found 2 days ago
Select Spirit Airlines flight, departing Fri, Nov 14 from Columbia to New Orleans, returning Mon, Nov 17, priced at $193 found 2 days ago

Biloxi economy flight packages

Price found within the past 48 hours. Click for updated prices.
The Barnett, part of JdV by Hyatt
4.0-star property

The Barnett, part of JdV by Hyatt

8.8/10 Excellent! (1,000 reviews)

Oct 4 - Oct 9

5 night stay

Columbia (CAE) to New Orleans (MSY)

Spirit Airlines • Non-stop • Coach

New Orleans (MSY) to Columbia (CAE)

Delta • Non-stop • Coach
Save 100% on your flight
Price was $820, price is now $538 per person
$538
per person
found 1 day ago
Spent the Independence Day holiday at The Barnett and had an amazing stay. The staff was so friendly and welcoming, and the property was spotless. The restored art deco building is beautiful, and the rooms are modern, spacious, and comfortable. I loved the rooftop pool with cocktails and great city views. With excellent dining options and spaces that work for both relaxing and getting things done, it’s the perfect mix of New Orleans charm and comfort. Highly recommend!

Reviewed on Jul 6, 2025

Sheraton New Orleans Hotel
4.0-star property

Sheraton New Orleans Hotel

8.8/10 Excellent! (1,227 reviews)

Oct 4 - Oct 9

5 night stay

Columbia (CAE) to New Orleans (MSY)

Spirit Airlines • Non-stop • Coach

New Orleans (MSY) to Columbia (CAE)

Delta • Non-stop • Coach
Save 100% on your flight
Price was $825, price is now $563 per person
$563
per person
found 1 day ago
Could use a deep cleaning, dark carpet shows up a lot of dust build up where vacuum doesn’t pick up.

Reviewed on Aug 11, 2025

Maison Dupuy Hotel
3.5-star property

Maison Dupuy Hotel

7.8/10 Good! (2,414 reviews)

Oct 4 - Oct 9

5 night stay

Columbia (CAE) to New Orleans (MSY)

Spirit Airlines • Non-stop • Coach

New Orleans (MSY) to Columbia (CAE)

Delta • Non-stop • Coach
Save 100% on your flight
Price was $784, price is now $550 per person
$550
per person
found 1 day ago
Very friendly staff, especially the front desk! Loved the balcony with pool views!

Reviewed on Mar 17, 2025

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More About Flying To Biloxi from Columbia

Route Information for Flights from Columbia to Biloxi

Origin Airport IATA Code
CAE
Destination Airport IATA Code
MOB
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Columbia to Biloxi

It has never been easier to find cheap Columbia to Biloxi flights. Orbitz has some of the best deals around to save you more money on your flight, hotel, and vacation package for the trip you have been waiting for.

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Get the Best Deals on Columbia to Biloxi Flights

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Pile Up Miles With Discount Air Tickets

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Frequently asked questions

What is the shortest flight from Columbia to Biloxi?
The trip from Columbia to Biloxi can be as quick as 2 hours and 24 minutes. With an easy flight time like this, why not grab some friends and organize a spur-of-the-moment getaway?
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.