$116 Cheap flight deals from Buffalo (BUF) to Vandalia (STL)
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Airfares from $116 One Way, $299 Round Trip from Buffalo to Vandalia
Prices starting at $299 for return flights and $116 for one-way flights to Vandalia were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Vandalia economy flight packages
The Knight Center at Washington University
Nov 19 - Nov 22
Buffalo (BUF) to St. Louis (STL)
St. Louis (STL) to Buffalo (BUF)
Reviewed on Oct 18, 2026
The Cheshire
Nov 19 - Nov 22
Buffalo (BUF) to St. Louis (STL)
St. Louis (STL) to Buffalo (BUF)
Spacious 3-Bedroom with King Bed
Nov 19 - Nov 22
Buffalo (BUF) to St. Louis (STL)
St. Louis (STL) to Buffalo (BUF)
Reviewed on Feb 1, 2026
More About Flying To Vandalia from Buffalo
Route Information for Flights from Buffalo to Vandalia
Origin Airport IATA Code | BUF |
|---|---|
Destination Airport IATA Code | STL |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Buffalo to Vandalia
Orbitz guarantees you low prices on flights from Buffalo to Vandalia. In addition to low fares on Buffalo to Vandalia flights, Orbitz offers fantastic savings on hotels, cruises, vacation packages, and more.
Earn Miles While Saving
Besides helping you fly for the lowest fares, Orbitz lets you earn miles for your frequent flyer program for certain flights from Buffalo to Vandalia. If you are a member of the frequent flyer or loyalty program offered by the airline you booked through Orbitz or a partner airline’s, simply add your frequent flyer number to your Orbitz reservation to get credit for your Buffalo to Vandalia flights.
Travel Planning Made Easy
We help take some of the anxiety out of your Buffalo to Vandalia flights with free flight alerts. We will let you know of flight changes and delays to your flights from Buffalo to Vandalia by email, voicemail, or text messages to your mobile phone. Alerts can also be sent to up to six other contacts to keep family and business teams informed.
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Orbitz lets you find the best deals on Buffalo to Vandalia flights while on the go, with our easy-to-use Android and iPhone mobile apps. Easily check flight status, gate numbers, and other flight details all in one place with our app—which is great when you are in a hurry. You can use the apps to access great mobile deals on flights and amazing hotel rooms.
Flights from Buffalo
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Buffalo Airports
Vandalia Airports
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.