$91 Cheap flight deals from Manchester (BOS) to O'Fallon (STL)

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This Weekend's Flight Deals from Manchester to O'Fallon

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Feb 20 - Fri, Feb 27
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$516 Roundtrip, found 6 days ago
$516
Roundtrip
found 6 days ago
Select Delta flight, departing Fri, Feb 20 from Logan Intl. to Lambert-St. Louis Intl., returning Fri, Feb 27, priced at $516 found 6 days ago
Fri, Feb 20 - Sat, Feb 21
MHT
Manchester-Boston Regional
STL
Lambert-St. Louis Intl.
$2,259 Roundtrip, found 6 days ago
$2,259
Roundtrip
found 6 days ago
Select United flight, departing Fri, Feb 20 from Manchester-Boston Regional to Lambert-St. Louis Intl., returning Sat, Feb 21, priced at $2,259 found 6 days ago

Airfares from $91 One Way, $180 Round Trip from Manchester to O'Fallon

Prices starting at $180 for return flights and $91 for one-way flights to O'Fallon were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, May 15 - Sun, May 17
BOS
Boston
STL
St. Louis
$180 Roundtrip, found 2 days ago
$180
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Fri, May 15 from Boston to St. Louis, returning Sun, May 17, priced at $180 found 2 days ago
Sun, Apr 12 - Thu, Apr 16
BOS
Boston
STL
St. Louis
$182 Roundtrip, found 1 day ago
$182
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sun, Apr 12 from Boston to St. Louis, returning Thu, Apr 16, priced at $182 found 1 day ago
Fri, May 15 - Sun, May 17
BOS
Boston
STL
St. Louis
$201 Roundtrip, found 5 hours ago
$201
Roundtrip
found 5 hours ago
Select Frontier Airlines flight, departing Fri, May 15 from Boston to St. Louis, returning Sun, May 17, priced at $201 found 5 hours ago
Wed, Mar 25 - Tue, Mar 31
BOS
Boston
STL
St. Louis
$279 Roundtrip, found 6 days ago
$279
Roundtrip
found 6 days ago
Select Southwest Airlines flight, departing Wed, Mar 25 from Boston to St. Louis, returning Tue, Mar 31, priced at $279 found 6 days ago
Tue, Apr 14 - Tue, Apr 21
BOS
Boston
STL
St. Louis
$294 Roundtrip, found 2 hours ago
$294
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Tue, Apr 14 from Boston to St. Louis, returning Tue, Apr 21, priced at $294 found 2 hours ago

O'Fallon economy flight packages

Price found within the past 48 hours. Click for updated prices.
21C Museum Hotel St Louis
4.5-star property

21C Museum Hotel St Louis

9/10 Wonderful! (1,458 reviews)

Apr 10 - Apr 12

2 night stay

Boston (BOS) to St. Louis (STL)

Southwest Airlines • Coach

St. Louis (STL) to Boston (BOS)

American Airlines • Coach
Price was $681, price is now $614 per person
$614
per person
found 1 day ago
The cafe that sold breakfast ran out of healthy options each morning (yogurt parfait cup/ overnight oats & quinoa $8 each) They had other plates, egg with meat, etc that looked nice fwiw. Cute gift shop in the cafe. Fashionable hotel with no real 'front desk' just a checkin counter, but volunteers were staffing a St. Louis info table in the lobby while we were there- very friendly. The bar/tapas restaurant across the lobby was fun, $$, and kitchen closed at 10 or so when our events got out so I didn't get to try it. LOVED the historic building, originally a YMCA, the handsome billiards room and the terrific tiled pool with vaulted ceiling- they don't make them like that anymore. Steam room, sauna, showers were great- bring a room towel in case the spa runs short! Open til 10:30p or 11p fyi. Art Museum on the 2nd floor is free to visitors, and had some challenging, gorgeous, funny, and thought-provoking art. Historic Campbell Mansion next door was a neat contrast and a quick peek into the high Victorian era. Glad I went, would stay again

Reviewed on Jan 14, 2026

Hotel Saint Louis, Autograph Collection
4.0-star property

Hotel Saint Louis, Autograph Collection

8.8/10 Excellent! (458 reviews)

Apr 10 - Apr 12

2 night stay

Boston (BOS) to St. Louis (STL)

Southwest Airlines • Coach

St. Louis (STL) to Boston (BOS)

American Airlines • Coach
Price was $855, price is now $747 per person
$747
per person
found 1 day ago
The receptionist at the front desk was very kind and helpful. I loved how clean my room was.

Reviewed on Aug 17, 2021

The Cheshire
4.0-star property

The Cheshire

8.6/10 Excellent! (1,002 reviews)

Apr 10 - Apr 12

2 night stay

Boston (BOS) to St. Louis (STL)

Southwest Airlines • Coach

St. Louis (STL) to Boston (BOS)

American Airlines • Coach
Price was $735, price is now $661 per person
$661
per person
found 1 day ago
We always stay here when in St. Louis. Love the place. Nice atmosphere, great pub.

Reviewed on Sep 2, 2025

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More About Flying To O'Fallon from Manchester

Route Information for Flights from Manchester to O'Fallon

Origin Airport IATA Code
BOS
Destination Airport IATA Code
STL
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Manchester to O'Fallon

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.