$125 Cheap flight deals from Des Moines (DSM) to Los Gatos (SJC)

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This Weekend's Flight Deals from Des Moines to Los Gatos

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Aug 28 - Mon, Aug 31
DSM
Des Moines Intl.
SFO
San Francisco Intl.
$423 Roundtrip, found 23 hours ago
$423
Roundtrip
found 23 hours ago
Select Frontier Airlines flight, departing Fri, Aug 28 from Des Moines Intl. to San Francisco Intl., returning Mon, Aug 31, priced at $423 found 23 hours ago

Airfares from $125 One Way, $251 Round Trip from Des Moines to Los Gatos

Prices starting at $251 for return flights and $125 for one-way flights to Los Gatos were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Oct 23 - Mon, Nov 2
DSM
Des Moines
SFO
San Francisco
$251 Roundtrip, found 5 days ago
$251
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Fri, Oct 23 from Des Moines to San Francisco, returning Mon, Nov 2, priced at $251 found 5 days ago
Fri, Oct 2 - Mon, Oct 5
DSM
Des Moines
SFO
San Francisco
$255 Roundtrip, found 3 days ago
$255
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Fri, Oct 2 from Des Moines to San Francisco, returning Mon, Oct 5, priced at $255 found 3 days ago
Fri, Nov 6 - Mon, Nov 9
DSM
Des Moines
SFO
San Francisco
$264 Roundtrip, found 13 hours ago
$264
Roundtrip
found 13 hours ago
Select Frontier Airlines flight, departing Fri, Nov 6 from Des Moines to San Francisco, returning Mon, Nov 9, priced at $264 found 13 hours ago
Tue, Nov 3 - Sat, Nov 7
DSM
Des Moines
SFO
San Francisco
$337 Roundtrip, found 13 hours ago
$337
Roundtrip
found 13 hours ago
Select Delta flight, departing Tue, Nov 3 from Des Moines to San Francisco, returning Sat, Nov 7, priced at $337 found 13 hours ago
Tue, Nov 3 - Sat, Nov 7
DSM
Des Moines
SFO
San Francisco
$337 Roundtrip, found 13 hours ago
$337
Roundtrip
found 13 hours ago
Select Southwest Airlines flight, departing Tue, Nov 3 from Des Moines to San Francisco, returning Sat, Nov 7, priced at $337 found 13 hours ago

Los Gatos economy flight packages

Price found within the past 48 hours. Click for updated prices.
Cathedral Hill Hotel
2.0-star property

Cathedral Hill Hotel

7.2/10 Good! (720 reviews)

Oct 12 - Oct 16

4 night stay

Des Moines (DSM) to San Francisco (SFO)

Frontier Airlines • Non-stop roundtrip • Coach
Price was $692, price is now $480 per person
$480
per person
found 18 hours ago
The hotel was what you get for the price. The building is in downtown surrounded by homeless and I wouldn’t recommend walking at night. The garage entrance is open and anyone can come in and out. However, the staff were nice and the rooms were of decent size. We only stayed for one night and wanted to be close to everything, it worked out perfectly for us.

Reviewed on Aug 20, 2026

The Grove Inn
3.0-star property

The Grove Inn

9.2/10 Wonderful! (729 reviews)

Oct 12 - Oct 16

4 night stay

Des Moines (DSM) to San Francisco (SFO)

Frontier Airlines • Non-stop roundtrip • Coach
Save 100% on your flight
Price was $1,179, price is now $777 per person
$777
per person
found 18 hours ago
Wow! We thoroughly enjoyed our stay at The Grove! The location was absolutely perfect. Very walkable and public transit near the hotel takes you to many main attractions. The location is convenient. The neighborhood is charming. The hotel is authentic to San Francisco. And the rooms were pristine clean. We actually live - hour away but decided to do a short day trip, and staying here and the surrounding areas gave us a totally different view of San Francisco (in the best way possible!). There are delicious and enjoyable shops, restaurants, coffee shops, and activities nearby including Fillmore Jazz Distric and Japantown (among others). There are a handful of beautiful parks with stunning views only a short distance away. Street parking is available, but can be tough to find and has restrictions during the week (but we are familiar with SF so were prepared). The rooms were very clean and the hotel was quiet and quaint. If I ever come back for a stay, I will hands down stay here again.

Reviewed on Aug 23, 2026

Bay Landing San Francisco Airport Hotel
3.0-star property

Bay Landing San Francisco Airport Hotel

9/10 Wonderful! (4,930 reviews)

Oct 12 - Oct 16

4 night stay

Des Moines (DSM) to San Francisco (SFO)

Frontier Airlines • Non-stop roundtrip • Coach
Price was $745, price is now $551 per person
$551
per person
found 18 hours ago

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More About Flying To Los Gatos from Des Moines

Route Information for Flights from Des Moines to Los Gatos

Origin Airport IATA Code
DSM
Destination Airport IATA Code
SJC
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Des Moines to Los Gatos

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.