
$155 Cheap flight deals from Memphis (MEM) to Des Moines (SEA)
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This Weekend's Flight Deals from Memphis to Des Moines
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $155 One Way, $380 Round Trip from Memphis to Des Moines
Prices starting at $380 for return flights and $155 for one-way flights to Des Moines were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Des Moines economy flight packages

The Belltown Inn
May 22 - May 25
Memphis (MEM) to Seattle (SEA)
Seattle (SEA) to Memphis (MEM)
Reviewed on Mar 25, 2026

Mayflower Park Hotel
May 22 - May 25
Memphis (MEM) to Seattle (SEA)
Seattle (SEA) to Memphis (MEM)
Reviewed on Nov 13, 2025

Mediterranean Inn
May 22 - May 25
Memphis (MEM) to Seattle (SEA)
Seattle (SEA) to Memphis (MEM)
Reviewed on Jan 2, 2026
More About Flying To Des Moines from Memphis
Route Information for Flights from Memphis to Des Moines
Origin Airport IATA Code | MEM |
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Destination Airport IATA Code | SEA |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Memphis to Des Moines
Those who want guaranteed low prices for Memphis to Des Moines flights only need to visit Orbitz. We take advantage of the latest mobile technologies to make sure you get the best bargain on your trip and that everything goes smoothly and according to your plans.
Take Advantage of Orbitz’s Amazing Customer Service on Memphis to Des Moines Flights
We will help you from booking to boarding on flights from Memphis to Des Moines. Whether you have questions about baggage limits, seat assignments or anything else, we will be there to answer them for you.
Get Great Recommendations For Travel Ideas On Orbitz.com
We do not only get the best bargains on flights from Memphis to Des Moines, but we can tell you what to do once you get there. Whether it is a music festival, hotel recommendation or list of local attractions, Orbitz can help make your travel plan more exciting.
Combine Car Rental With Your Discount Flight For Even More Savings
Not only can we get bargain deals on flights from Memphis to Des Moines but we can book your transport as well. By combining car rental with Memphis to Des Moines flights, you can be sure to save money and start moving as soon as you hit the ground.
Use Orbitz On The Go To Stay Informed Using Your Smartphone
This convenient app works with most smartphones and allows you to see the status of flights from Memphis to Des Moines. You don’t have to worry, if something goes wrong, we’ll let you know.
Flights from Memphis
- Memphis to Dallas
- Memphis to Atlanta
- Memphis to Houston
- Memphis to Chicago
- Memphis to Orlando
- Memphis to New York
- Memphis to Phoenix
- Memphis to Los Angeles
- Memphis to Charlotte
- Memphis to Toronto
- Memphis to Detroit
- Memphis to Rome
- Memphis to San Francisco
- Memphis to Washington
- Memphis to Kansas City
- Memphis to London
- Memphis to Sacramento
- Memphis to Harrisburg - Hershey
- Memphis to New Orleans
- Memphis to Anchorage
Memphis Airports
Des Moines Airports
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.



