Cheap flights from SYR to EYW (Hancock Intl. to Key West Intl.)

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Cheap Flights from SYR to EYW starting at $175 One Way, $349 Round Trip

Prices starting at $349 for return flights and $175 for one-way flights to Key West Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Mon, Feb 1 - Fri, Feb 5
SYR
Syracuse
EYW
Key West
$349 Roundtrip, found 3 days ago
$349
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Feb 1 from Syracuse to Key West, returning Fri, Feb 5, priced at $349 found 3 days ago
Tue, Apr 14 - Wed, Apr 22
SYR
Syracuse
EYW
Key West
$351 Roundtrip, found 3 days ago
$351
Roundtrip
found 3 days ago
Select United flight, departing Tue, Apr 14 from Syracuse to Key West, returning Wed, Apr 22, priced at $351 found 3 days ago
Mon, Feb 1 - Fri, Feb 5
SYR
Syracuse
EYW
Key West
$354 Roundtrip, found 3 days ago
$354
Roundtrip
found 3 days ago
Select Delta flight, departing Mon, Feb 1 from Syracuse to Key West, returning Fri, Feb 5, priced at $354 found 3 days ago
Wed, Apr 29 - Fri, May 1
SYR
Syracuse
EYW
Key West
$355 Roundtrip, found 4 days ago
$355
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Apr 29 from Syracuse to Key West, returning Fri, May 1, priced at $355 found 4 days ago
Tue, Apr 14 - Wed, Apr 22
SYR
Syracuse
EYW
Key West
$356 Roundtrip, found 3 days ago
$356
Roundtrip
found 3 days ago
Select United flight, departing Tue, Apr 14 from Syracuse to Key West, returning Wed, Apr 22, priced at $356 found 3 days ago

Hotel Ideas near Key West Intl.

Airport Hotels near Key West Intl.

Hyatt Vacation Club at Windward Pointe, Key West

Hyatt Vacation Club at Windward Pointe, Key West

3.5 out of 5
3675 South Roosevelt Boulevard Key West FL
$434 nightly
The price is $489 total per night from May 5 to May 6
$489 total
May 5 - May 6
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, free parking, and a snack bar/deli. Our guests praise the pool and the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,026 reviews)
We were a group of 6 so the 2 bedroom worked well for us. It was nice to have a full kitchen to cook meals if we wanted. Beds/mattresses could use a refresh, a little uncomfortable and the bath tub didn’t have any hot water but otherwise room was fine. The grounds are beautiful and the pool and its ...

Reviewed on Apr 9, 2026

Hyatt Vacation Club at Windward Pointe, Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
$287 nightly
The price is $323 total per night from May 10 to May 11
$323 total
May 10 - May 11
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,325 reviews)
It was a pleasant stay with our grandchildren and dogs. Staff was excellent and helpful.

Reviewed on Apr 7, 2026

Hampton Inn Key West FL
DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
$235 nightly
The price is $264 total per night from May 10 to May 11
$264 total
May 10 - May 11
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.2/10 Very Good! (1,009 reviews)
The staff were all very friendly and helpful, and took time to answer questions and make sure we had what we needed. The room was smaller than what it looked like in the photos, but it was not small. There was plenty of room and the space was very clean. The breakfast, while good, was very much like ...

Reviewed on Apr 8, 2026

DoubleTree Resort by Hilton Grand Key - Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Key West

Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
$235 nightly
The price is $265 total per night from May 10 to May 11
$265 total
May 10 - May 11
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.2/10 Very Good! (2,062 reviews)
Fair price for the property in this area. Kind of a hassle to take the shuttle every time you wanted to go downtown. Just need to plan for that to make reservations for the shuttle. The pool was popular so if you want 2 loungers together by the pool go early. It is a kid friendly resort. The drinks ...

Reviewed on Apr 9, 2026

Blue Flamingo Resort Key West
Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street Key West FL
$415 nightly
The price is $467 total per night from May 10 to May 11
$467 total
May 10 - May 11
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.8/10 Excellent! (3,196 reviews)
Great experience

Reviewed on Apr 9, 2026

Southernmost Beach Resort and Guesthouses
Margaritaville Beach House Key West

Margaritaville Beach House Key West

4 out of 5
2001 South Roosevelt Boulevard Key West FL
$289 nightly
The price is $326 total per night from May 6 to May 7
$326 total
May 6 - May 7
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the pool and the restaurant ...
8.8/10 Excellent! (1,808 reviews)
Hotel pictures online have not been updated to current condition. All room doors are located outside. Gaps under the door which can let bugs in. After checking into our room, my family brought dinner to the room. After about 15 mins our counter and food was covered in ants. Ants were also in the ...

Reviewed on Apr 8, 2026

Margaritaville Beach House Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Key West Hotels With Airport Transportation

DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
$235 nightly
The price is $264 total per night from May 10 to May 11
$264 total
May 10 - May 11
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.2/10 Very Good! (1,009 reviews)
The staff were all very friendly and helpful, and took time to answer questions and make sure we had what we needed. The room was smaller than what it looked like in the photos, but it was not small. There was plenty of room and the space was very clean. The breakfast, while good, was very much like ...

Reviewed on Apr 8, 2026

DoubleTree Resort by Hilton Grand Key - Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
$287 nightly
The price is $323 total per night from May 10 to May 11
$323 total
May 10 - May 11
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,325 reviews)
It was a pleasant stay with our grandchildren and dogs. Staff was excellent and helpful.

Reviewed on Apr 7, 2026

Hampton Inn Key West FL
Eden House

Eden House

4 out of 5
1015 Fleming St Key West FL
$275 nightly
The price is $310 total per night from May 10 to May 11
$310 total
May 10 - May 11
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, in-room massages, and a 24-hour front desk. Our guests praise the pool and the helpful staff in our reviews. ...
9/10 Wonderful! (1,000 reviews)
Overall a really nice place. Easy walk and bike ride to all the local sites. Only issue, if you can call it that, is the room was very small for the price.

Reviewed on Apr 9, 2026

Eden House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Key West Hotels

Southwinds Motel

Southwinds Motel

2 out of 5
1321 Simonton Street Key West FL
$252 nightly
The price is $284 total per night from May 10 to May 11
$284 total
May 10 - May 11
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,300 reviews)
The room was very clean and the staff was great. I really enjoyed the heated pool.

Reviewed on Apr 8, 2026

Southwinds Motel
Seashell Motel

Seashell Motel

1.5 out of 5
718 South Street Key West FL
$208 nightly
The price is $234 total per night from Apr 12 to Apr 13
$234 total
Apr 12 - Apr 13
Total with taxes and fees
Stay at this hostel in Key West. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8/10 Very Good! (1,005 reviews)
The room was nice and clean. Very pleasant staff and great parking. The only thing missing was the whole pool area. It was completely under construction but overall a nice place

Reviewed on Apr 9, 2026

Seashell Motel
Duval House

Duval House

3 out of 5
815 Duval St Key West FL
$271 nightly
The price is $302 total per night from Apr 20 to Apr 21
$302 total
Apr 20 - Apr 21
Total with taxes and fees
Stay at this B&B in Key West. Enjoy parking (surcharge), daily housekeeping, and a garden. Our guests praise the breakfast and the pool in our reviews. Popular ...
9.4/10 Exceptional! (1,013 reviews)
Enjoyed our stay. Room was clean and orderly. They welcomed us when we got there. Gave us a tour of the property. Staff was helpful accommodating.

Reviewed on Apr 9, 2026

Duval House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Key West

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street Key West FL
$415 nightly
The price is $467 total per night from May 10 to May 11
$467 total
May 10 - May 11
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.8/10 Excellent! (3,196 reviews)
Great experience

Reviewed on Apr 9, 2026

Southernmost Beach Resort and Guesthouses
Margaritaville Beach House Key West

Margaritaville Beach House Key West

4 out of 5
2001 South Roosevelt Blvd Key West FL
Book a stay at this beach hotel in Key West. Enjoy free parking, 2 restaurants, and breakfast (surcharge). Popular attractions Duval Street and Smathers Beach ...
8.4/10 Very Good! (999 reviews)

Families like: Outdoor pool, babysitting, close to beach, bicycle rentals

Travelers say...
Great visit

Reviewed on Feb 27, 2026

Get rates
Margaritaville Beach House Key West
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
$235 nightly
The price is $265 total per night from May 10 to May 11
$265 total
May 10 - May 11
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.2/10 Very Good! (2,062 reviews)

Families like: Outdoor pools, miniature golf, game room, bicycle rentals

Travelers say...
Fair price for the property in this area. Kind of a hassle to take the shuttle every time you wanted to go downtown. Just need to plan for that to make reservations for the shuttle. The pool was popular so if you want 2 loungers together by the pool go early. It is a kid friendly resort. The drinks ...

Reviewed on Apr 9, 2026

Blue Flamingo Resort Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

SYR to EYW Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
SYR Address & GPS
Address:
City Hall
Syracuse NY, 13212
United States
IATA Code:
SYR
Longitude:
-76.112231
Latitude:
43.113984
Time Zone:
America/New_York
EYW Address & GPS
Address:
3491 South Roosevelt Boulevard
Key West FL, 33040-5260
United States
IATA Code:
EYW
Longitude:
-81.75501
Latitude:
24.553574
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from Syracuse Hancock Intl. Airport to Key West Intl. Airport?
Unfortunately, you won't find any direct flights on this route. But American Airlines, United Airlines and Delta Air Lines can get you from Hancock Intl. Airport (SYR) to Key West Intl. Airport (EYW) with only one stopover.
What is the shortest flight from Hancock Intl. Airport (SYR) to Key West Intl. Airport (EYW)?
Use the opportunity to relax on your trip from Syracuse to Key West. The quickest flight time from Hancock Intl. Airport (SYR) to Key West Intl. Airport is 4 hours and 57 minutes, which gives you more than enough time to enjoy a wine or get engrossed in a book.
How many hours flight from Hancock Intl. Airport (SYR) to Key West Intl. Airport?
From SYR to Key West Intl. Airport, you'll be in the sky for roughly 5 hours and 3 minutes. Get comfy, grab a wine and take out your noise-canceling earphones. It's time for a movie marathon.
What airlines have the most flights from Syracuse Hancock Intl. Airport to Key West Intl. Airport?
Right now, no airlines have direct flights between Syracuse Hancock Intl. Airport and Key West Intl. Airport. But don't panic! There are several single or multi-stop options available.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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