Cheap flights from STL to EYW (Lambert-St. Louis Intl. to Key West Intl.)
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
Cheap Flights from STL to EYW starting at $271 One Way, $223 Round Trip
Prices starting at $223 for return flights and $271 for one-way flights to Key West Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
STL
St. Louis
EYW
Key West
$223 Roundtrip, found 1 day ago
$223
Roundtrip
found 1 day ago
STL
St. Louis
EYW
Key West
$223 Roundtrip, found 1 day ago
$223
Roundtrip
found 1 day ago
STL
St. Louis
EYW
Key West
$223 Roundtrip, found 1 day ago
$223
Roundtrip
found 1 day ago
STL
St. Louis
EYW
Key West
$228 Roundtrip, found 1 day ago
$228
Roundtrip
found 1 day ago
STL
St. Louis
EYW
Key West
$241 Roundtrip, found 1 day ago
$241
Roundtrip
found 1 day ago
Hotel Ideas near Key West Intl.
Airport Hotels near Key West Intl.
Hyatt Vacation Club at Windward Pointe, Key West
3675 South Roosevelt Boulevard, Key West, FL
$309 nightly
The price is $348 total per night from Dec 1 to Dec 2
$348 total
Dec 1 - Dec 2
Total with taxes and fees
Stay at this 3.5-star eco-certified hotel in Key West. Enjoy free WiFi, free parking, and a snack bar/deli. Our guests praise the pool and the helpful staff ...
9.4/10 Exceptional! (1,047 reviews)
All very good!
Reviewed on Nov 4, 2025
Hampton Inn Key West FL
3755 S Roosevelt Blvd, Key West, FL
$203 nightly
The price is $229 total per night from Nov 30 to Dec 1
$229 total
Nov 30 - Dec 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,252 reviews)
It all worked and was stress free.
Reviewed on Nov 6, 2025
DoubleTree Resort by Hilton Grand Key - Key West
3990 S Roosevelt Blvd, Key West, FL
$169 nightly
The price is $190 total per night from Nov 18 to Nov 19
$190 total
Nov 18 - Nov 19
Total with taxes and fees
Stay at this 4-star business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8/10 Very Good! (1,016 reviews)
Nice and clean, very curtious staff. Free Shuttle service was great. Food in restaurant was great.
Reviewed on Nov 3, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels In Key West
Oceans Edge Key West Resort, Hotel & Marina
5950 Peninsular Avenue, Key West, FL
$208 nightly
The price is $234 total per night from Nov 30 to Dec 1
$234 total
Nov 30 - Dec 1
Total with taxes and fees
Stay at this 4-star luxury hotel in Key West. Enjoy free WiFi, 6 outdoor pools, and a marina. Our guests praise the pool and the restaurant in our reviews. Popular ...
8.8/10 Excellent! (1,728 reviews)
We’ve stayed here twice now. Staff is great, the shuttle into town is super convenient (hi Jeffrey!). We love that you can use the kayaks or paddleboards every day. The tiki hut crew is the best! The place is clean and I feel safe walking around there. It’s well lit and easy to navigate.
Reviewed on Nov 2, 2025
Blue Flamingo Resort Key West
3820 North Roosevelt Boulevard, Key West, FL
$157 nightly
The price is $177 total per night from Nov 18 to Nov 19
$177 total
Nov 18 - Nov 19
Total with taxes and fees
Stay at this 4-star family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
7.8/10 Good! (1,663 reviews)
Great staff!
Reviewed on Nov 6, 2025
Beachside Resort & Residences
3841 N Roosevelt Blvd, Key West, FL
$193 nightly
The price is $217 total per night from Nov 17 to Nov 18
$217 total
Nov 17 - Nov 18
Total with taxes and fees
Stay at this 3.5-star beach hotel in Key West. Enjoy free WiFi, 2 restaurants, and a private beach. Our guests praise the pool and the helpful staff in our reviews. ...
8.6/10 Excellent! (1,654 reviews)
Loved the atmosphere. Beautiful & clean room. Heated pool well maintained and open 24 hours. Plan on staying again. future
Reviewed on Nov 2, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Key West Hotels With Airport Transportation
DoubleTree Resort by Hilton Grand Key - Key West
3990 S Roosevelt Blvd, Key West, FL
$169 nightly
The price is $190 total per night from Nov 18 to Nov 19
$190 total
Nov 18 - Nov 19
Total with taxes and fees
Stay at this 4-star business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8/10 Very Good! (1,016 reviews)
Nice and clean, very curtious staff. Free Shuttle service was great. Food in restaurant was great.
Reviewed on Nov 3, 2025
Hampton Inn Key West FL
3755 S Roosevelt Blvd, Key West, FL
$203 nightly
The price is $229 total per night from Nov 30 to Dec 1
$229 total
Nov 30 - Dec 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,252 reviews)
It all worked and was stress free.
Reviewed on Nov 6, 2025
Eden House
1015 Fleming St, Key West, FL
$250 nightly
The price is $281 total per night from Nov 17 to Nov 18
$281 total
Nov 17 - Nov 18
Total with taxes and fees
Stay at this 3.5-star hotel in Key West. Enjoy free WiFi, in-room massages, and a 24-hour front desk. Our guests praise the pool and the helpful staff in our ...
9/10 Wonderful! (1,004 reviews)
The room was clean, the staff very friendly and we loved the tiki bar!
Reviewed on Nov 2, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Low Priced Key West Hotels
Southwinds Motel
1321 Simonton Street, Key West, FL
$164 nightly
The price is $185 total per night from Nov 18 to Nov 19
$185 total
Nov 18 - Nov 19
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and a 24-hour front desk. Our guests praise the breakfast and the pool in our reviews. ...
8.8/10 Excellent! (1,223 reviews)
The room wasn't spotless but was still clean. The inside of draws could be vaccumed or wiped down more. Staff was courteous. Heated pool wasn't so heated as they said. For the Queen bedroom, the bathroom toiletries wasn't much as far as soap and shampoo.
Reviewed on Nov 3, 2025
Seashell Motel
718 South Street, Key West, FL
$131 nightly
The price is $147 total per night from Nov 12 to Nov 13
$147 total
Nov 12 - Nov 13
Total with taxes and fees
Stay at this hostel in Key West. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7.8/10 Good! (1,012 reviews)
The rooms are small but very clean. I’ve stayed here a few times and it’s always been nice.
Reviewed on Oct 28, 2025
Duval House
815 Duval St, Key West, FL
$177 nightly
The price is $196 total per night from Nov 12 to Nov 13
$196 total
Nov 12 - Nov 13
Total with taxes and fees
Stay at this 3-star B&B in Key West. Enjoy parking (surcharge), daily housekeeping, and a garden. Our guests praise the breakfast and the pool in our reviews. ...
9.4/10 Exceptional! (1,041 reviews)
Was awesome! We will be back
Reviewed on Nov 3, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Key West
Southernmost Beach Resort and Guesthouses
1319 Duval Street, Key West, FL
$242 nightly
The price is $272 total per night from Nov 30 to Dec 1
$272 total
Nov 30 - Dec 1
Total with taxes and fees
Stay at this 4-star beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the bar in our reviews. ...
8.6/10 Excellent! (2,845 reviews)
The lady who checked us in was a fast talker. She seemed in charge and wore a flower in her hair but it was obvious she was only going through the motions.. while she was training a new associate. I’m not sure she likes the hospitality business anymore.
Reviewed on Nov 3, 2025
Margaritaville Beach House Key West
2001 South Roosevelt Blvd, Key West, FL
Stay at this 4-star beach hotel in Key West. Enjoy free parking, 2 restaurants, and breakfast (surcharge). Popular attractions Duval Street and Smathers Beach ...
8.2/10 Very Good! (1,000 reviews)
Families like: Outdoor pool, babysitting, close to beach, bicycle rentals
Travelers say...
Stayed here many times. Easy in and out, plenty of parking. Great friendly staff
Reviewed on Sep 1, 2025
Blue Flamingo Resort Key West
3820 North Roosevelt Boulevard, Key West, FL
$157 nightly
The price is $177 total per night from Nov 18 to Nov 19
$177 total
Nov 18 - Nov 19
Total with taxes and fees
Stay at this 4-star family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
7.8/10 Good! (1,663 reviews)
Families like: Outdoor pools, miniature golf, game room, bicycle rentals
Travelers say...
Great staff!
Reviewed on Nov 6, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
STL to EYW Route Info
Origin Airport | |
|---|---|
Destination Airport | |
Number Of Airlines Serving | |
Distance | |
Shortest Flight Departure Time | |
Shortest Flight Departure Date |
- Route Reviews
- Airport Locations
- More Popular Flights
- Top Trending
- Flights from Other Cities
- Flights From Other Airports
- Great Travel Ideas
STL Address & GPS
Address:
10701 Lambert International Blvd.
Saint Louis MO, 63145
United States
IATA Code:
STL
Longitude:
-90.379002
Latitude:
38.748707
Time Zone:
America/Chicago
EYW Address & GPS
Address:
3491 South Roosevelt Boulevard
Key West FL, 33040-5260
United States
IATA Code:
EYW
Longitude:
-81.75501
Latitude:
24.553574
Time Zone:
America/New_York
Other Flights from Lambert-St. Louis Intl. Airport (STL)
Other Flights to Key West Intl. Airport (EYW)
- Abraham Lincoln Capital Airport (SPI)
- Quincy Regional-Baldwin Field Airport (UIN)
- Columbia Regional Airport (COU)
- Williamson County Regional Airport (MWA)
- Decatur Airport (DEC)
- Cape Girardeau Municipal Airport (CGI)
- St. Robert Regional Airport (TBN)
- Cairo Regional Airport (CIR)
- Greater Peoria Regional Airport (PIA)
- Central Illinois Regional Airport (BMI)
Top Trending
Flights
- Flights from Washington (DCA) to Orlando (MCO)
- Flights from Boston (BOS) to Orlando (MCO)
- Flights from Windsor Locks (BDL) to Orlando (MCO)
- Flights from New York (LGA) to Miami (MIA)
- Flights from New York (JFK) to Las Vegas (LAS)
- Flights from New York (LGA) to Fort Lauderdale (FLL)
- Flights from Orlando (MCO) to Los Angeles (LAX)
- Flights from Detroit (DTW) to Orlando (MCO)
- Flights from Washington (DCA) to Miami (MIA)
- Flights from Los Angeles (LAX) to Dallas (DFW)
- Flights from Orlando (MCO) to New York (LGA)
- Flights from Seattle (SEA) to San Diego (SAN)
- Flights from Baltimore (BWI) to Miami (MIA)
- Flights from New York (JFK) to Fort Lauderdale (FLL)
- Flights from Baltimore (BWI) to Dallas (DFW)
- Flights from Los Angeles (LAX) to Orlando (MCO)
- Flights from Newark (EWR) to Orlando (MCO)
- Flights from Santa Ana (SNA) to Las Vegas (LAS)
- Flights from New York (LGA) to Orlando (MCO)
- Flights from Orlando (MCO) to New York (JFK)
- Flights from Orlando (MCO) to Newark (EWR)
- Flights from Chicago (ORD) to Orlando (MCO)
- Flights from Orlando (MCO) to San Juan (SJU)
- Flights from Philadelphia (PHL) to Orlando (MCO)
- Flights from Baltimore (BWI) to Orlando (MCO)
- Flights from New York (JFK) to Orlando (MCO)
- Flights from New York (JFK) to Miami (MIA)
- Flights from Dallas (DFW) to Paris (CDG)
- Flights from Raleigh (RDU) to Orlando (MCO)
- Flights from Washington (DCA) to Boston (BOS)
Frequently asked questions
Map To Nearby Hotels
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.