Cheap flights from SNA to GSP (John Wayne to Greenville-Spartanburg Intl.)

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Cheap Flights from SNA to GSP starting at $201 One Way, $417 Round Trip

Prices starting at $417 for return flights and $201 for one-way flights to Greenville-Spartanburg Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Mon, Jun 8 - Wed, Jun 17
SNA
Orange County
GSP
Greenville
$417 Roundtrip, found 20 hours ago
$417
Roundtrip
found 20 hours ago
Select Southwest Airlines flight, departing Mon, Jun 8 from Orange County to Greenville, returning Wed, Jun 17, priced at $417 found 20 hours ago
Tue, Jun 9 - Wed, Jun 17
SNA
Orange County
GSP
Greenville
$437 Roundtrip, found 20 hours ago
$437
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Tue, Jun 9 from Orange County to Greenville, returning Wed, Jun 17, priced at $437 found 20 hours ago
Mon, Jun 8 - Wed, Jun 17
SNA
Orange County
GSP
Greenville
$437 Roundtrip, found 20 hours ago
$437
Roundtrip
found 20 hours ago
Select Southwest Airlines flight, departing Mon, Jun 8 from Orange County to Greenville, returning Wed, Jun 17, priced at $437 found 20 hours ago
Tue, Jun 9 - Wed, Jun 17
SNA
Orange County
GSP
Greenville
$442 Roundtrip, found 20 hours ago
$442
Roundtrip
found 20 hours ago
Select Southwest Airlines flight, departing Tue, Jun 9 from Orange County to Greenville, returning Wed, Jun 17, priced at $442 found 20 hours ago
Mon, Jun 8 - Wed, Jun 17
SNA
Orange County
GSP
Greenville
$444 Roundtrip, found 20 hours ago
$444
Roundtrip
found 20 hours ago
Select Southwest Airlines flight, departing Mon, Jun 8 from Orange County to Greenville, returning Wed, Jun 17, priced at $444 found 20 hours ago

Hotel Ideas near Greenville-Spartanburg Intl.

Airport Hotels near Greenville-Spartanburg Intl.

MainStay Suites Greenville Airport

MainStay Suites Greenville Airport

2.5 out of 5
2671 Dry Pocket Rd Greer SC
$72 nightly
The price is $79 total per night from Jun 10 to Jun 11
$79 total
Jun 10 - Jun 11
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.6/10 Good! (689 reviews)
The room is exactly as pictured on the website. I isn't fancy but it is clean and surprisingly quiet considering there were a lot of guests there for a soccer tournament. The kitchen in the room is a to nice bonus. Especially for families with children. The morning breakfast was good, again not fancy. ...

Reviewed on May 8, 2026

MainStay Suites Greenville Airport
Woodspring Suites Greenville Airport

Woodspring Suites Greenville Airport

2.5 out of 5
205 Entertainment Blvd Greenville SC
$71 nightly
The price is $79 total per night from May 12 to May 13
$79 total
May 12 - May 13
Total with taxes and fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and laundry facilities. Popular attractions Haywood Mall and Topgolf ...
8/10 Very Good! (435 reviews)
Clean, but noisy

Reviewed on May 8, 2026

Woodspring Suites Greenville Airport
Hampton Inn & Suites Greenville Airport, SC

Hampton Inn & Suites Greenville Airport, SC

2.5 out of 5
128 The Parkway Greenville SC
$116 nightly
The price is $128 total per night from Jun 7 to Jun 8
$128 total
Jun 7 - Jun 8
Total with taxes and fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,006 reviews)
Staff was very friendly and accommodating. They were able to allow us last minute early check in which was very much appreciated with the jet lag. Breakfast was wonderful with many options

Reviewed on May 2, 2026

Hampton Inn & Suites Greenville Airport, SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Greenville

Courtyard Greenville-Spartanburg by Marriott

Courtyard Greenville-Spartanburg by Marriott

3 out of 5
115 The Pkwy Greer SC
$121 nightly
The price is $133 total per night from Jun 4 to Jun 5
$133 total
Jun 4 - Jun 5
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (665 reviews)
Staff. Clean room. Comfortable and close to highway food etc.

Reviewed on May 4, 2026

Courtyard Greenville-Spartanburg by Marriott
MainStay Suites Greenville Airport

MainStay Suites Greenville Airport

2.5 out of 5
2671 Dry Pocket Rd Greer SC
$72 nightly
The price is $79 total per night from Jun 10 to Jun 11
$79 total
Jun 10 - Jun 11
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.6/10 Good! (689 reviews)
The room is exactly as pictured on the website. I isn't fancy but it is clean and surprisingly quiet considering there were a lot of guests there for a soccer tournament. The kitchen in the room is a to nice bonus. Especially for families with children. The morning breakfast was good, again not fancy. ...

Reviewed on May 8, 2026

MainStay Suites Greenville Airport
Comfort Inn & Suites Greer - Greenville

Comfort Inn & Suites Greer - Greenville

2.5 out of 5
1315 W Wade Hampton Blvd Greer SC
$104 nightly
The price is $114 total per night from May 17 to May 18
$114 total
May 17 - May 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (788 reviews)
Very nice, well taken care of. Comfortable bed abd spacious room, shower was large and had a great shower head. Had a great choice of breakfast foofs to choose from. Will use Comfort Inn & Suites again.

Reviewed on May 7, 2026

Comfort Inn & Suites Greer - Greenville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Greenville Hotels With Airport Transportation

Holiday Inn Express & Suites Greenville Airport by IHG

Holiday Inn Express & Suites Greenville Airport by IHG

3.5 out of 5
2681 Dry Pocket Road Greer SC
$110 nightly
The price is $121 total per night from Jun 7 to Jun 8
$121 total
Jun 7 - Jun 8
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (844 reviews)
Our room was dirty upon arrival. Inside was very unkept and dirty. Stains and holes in the wall. No sheets for the pullout couch bed which was stained. One of the queen beds was literally blocking and aotting on the air unit. Thus making it very cold and uncomfortable for the person or persons occupying ...

Reviewed on May 3, 2026

Holiday Inn Express & Suites Greenville Airport by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Greenville

Comfort Inn & Suites Greer - Greenville

Comfort Inn & Suites Greer - Greenville

2.5 out of 5
1315 W Wade Hampton Blvd Greer SC
$104 nightly
The price is $114 total per night from May 17 to May 18
$114 total
May 17 - May 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (788 reviews)
Very nice, well taken care of. Comfortable bed abd spacious room, shower was large and had a great shower head. Had a great choice of breakfast foofs to choose from. Will use Comfort Inn & Suites again.

Reviewed on May 7, 2026

Comfort Inn & Suites Greer - Greenville
Holiday Inn Express & Suites Greenville Airport by IHG

Holiday Inn Express & Suites Greenville Airport by IHG

3.5 out of 5
2681 Dry Pocket Road Greer SC
$110 nightly
The price is $121 total per night from Jun 7 to Jun 8
$121 total
Jun 7 - Jun 8
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (844 reviews)
Our room was dirty upon arrival. Inside was very unkept and dirty. Stains and holes in the wall. No sheets for the pullout couch bed which was stained. One of the queen beds was literally blocking and aotting on the air unit. Thus making it very cold and uncomfortable for the person or persons occupying ...

Reviewed on May 3, 2026

Holiday Inn Express & Suites Greenville Airport by IHG
Quality Inn Greer - Greenville

Quality Inn Greer - Greenville

2.5 out of 5
611 W Wade Hampton Blvd Greer SC
$77 nightly
The price is $84 total per night from May 17 to May 18
$84 total
May 17 - May 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7/10 Good! (352 reviews)
It amazes me that such an outdated and ill-kept facility charges over $100 per night. The room had dead bugs in the corner and stains on the bed cover. Thankfully I am glad to report there were no bed bugs in our room.

Reviewed on May 5, 2026

Quality Inn Greer - Greenville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

SNA to GSP Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
SNA Address & GPS
Address:
18601 Airport Way
Santa Ana CA, 92707
United States
IATA Code:
SNA
Longitude:
-117.860538
Latitude:
33.680201
Time Zone:
America/Los_Angeles
GSP Address & GPS
Address:
2000 GPS Drive, Suite 1
Greenville SC, 29651-9202
United States
IATA Code:
GSP
Longitude:
-82.217053
Latitude:
34.890569
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from SNA to Roger Milliken Field?
Unfortunately, there are no direct flights on this route. But American Airlines, United Airlines and Delta Air Lines can fly you from John Wayne Airport to Greenville-Spartanburg Intl. Airport (GSP) with only one stopover.
What is the shortest flight from John Wayne Airport to GSP?
The quickest you can fly from John Wayne Airport to Greenville-Spartanburg Intl. Airport (GSP) is 5 hours and 44 minutes. Slip a few things into your hand luggage to keep you amused, like a magazine or a portable board game.
How many hours flight from SNA to Roger Milliken Field?
On average, the journey from John Wayne Airport (SNA) to Roger Milliken Field takes 5 hours and 50 minutes. If you would like to be as comfortable as possible, consider upgrading your seat using miles or cash.
What airlines have the most flights from John Wayne Airport (SNA) to GSP?
You'll need to make one or more stopovers if you need to get from Santa Ana to Greenville. Right now, you won't find any airlines that offer nonstop flights on this route.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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