Cheap flights from MHT to EYW (Manchester-Boston Regional to Key West Intl.)

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Cheap Flights from MHT to EYW starting at $163 One Way, $317 Round Trip

Prices starting at $317 for return flights and $163 for one-way flights to Key West Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Sep 15 - Sat, Sep 19
MHT
Manchester
EYW
Key West
$317 Roundtrip, found 1 day ago
$317
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Sep 15 from Manchester to Key West, returning Sat, Sep 19, priced at $317 found 1 day ago
Fri, May 15 - Tue, May 19
MHT
Manchester
EYW
Key West
$357 Roundtrip, found 7 hours ago
$357
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Fri, May 15 from Manchester to Key West, returning Tue, May 19, priced at $357 found 7 hours ago
Tue, Sep 15 - Sat, Sep 19
MHT
Manchester
EYW
Key West
$358 Roundtrip, found 1 day ago
$358
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Sep 15 from Manchester to Key West, returning Sat, Sep 19, priced at $358 found 1 day ago
Tue, Sep 15 - Sat, Sep 19
MHT
Manchester
EYW
Key West
$363 Roundtrip, found 1 day ago
$363
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Sep 15 from Manchester to Key West, returning Sat, Sep 19, priced at $363 found 1 day ago
Sun, May 3 - Thu, May 7
MHT
Manchester
EYW
Key West
$377 Roundtrip, found 1 day ago
$377
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sun, May 3 from Manchester to Key West, returning Thu, May 7, priced at $377 found 1 day ago

Hotel Ideas near Key West Intl.

Airport Hotels near Key West Intl.

Hyatt Vacation Club at Windward Pointe, Key West

Hyatt Vacation Club at Windward Pointe, Key West

3.5 out of 5
3675 South Roosevelt Boulevard Key West FL
$524 nightly
The price is $589 total per night from Mar 29 to Mar 30
$589 total
Mar 29 - Mar 30
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, free parking, and a snack bar/deli. Our guests praise the pool and the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,002 reviews)
Everything was so clean.

Reviewed on Mar 1, 2026

Hyatt Vacation Club at Windward Pointe, Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
$404 nightly
The price is $455 total per night from Mar 30 to Mar 31
$455 total
Mar 30 - Mar 31
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,323 reviews)
Over booked and even tho I reserved a room with a balcony almost 2 months ago they gave us a room w no view, no balcony and there were large ants in the bathroom. Only thing they gave us was a coupon for 2 free drinks, an “I’m sorry” and that’s it. We have stayed here multiple times but unfortunately ...

Reviewed on Feb 28, 2026

Hampton Inn Key West FL
DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
$417 nightly
The price is $470 total per night from Mar 8 to Mar 9
$470 total
Mar 8 - Mar 9
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.2/10 Very Good! (1,002 reviews)
Nice clean hotel. Smathers beach right down the road. Shuttle to Duval and the airport were very nice.

Reviewed on Feb 24, 2026

DoubleTree Resort by Hilton Grand Key - Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Key West

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street Key West FL
$530 nightly
The price is $596 total per night from Mar 12 to Mar 13
$596 total
Mar 12 - Mar 13
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.8/10 Excellent! (3,099 reviews)
Staff were very friendly and accommodating. Room was very clean. I really enjoyed the property.

Reviewed on Mar 1, 2026

Southernmost Beach Resort and Guesthouses
Ibis Bay Beach Resort

Ibis Bay Beach Resort

2.5 out of 5
3101 N. Roosevelt Blvd Key West FL
$333 nightly
The price is $375 total per night from Mar 5 to Mar 6
$375 total
Mar 5 - Mar 6
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free breakfast, free WiFi, and a private beach. Our guests praise the breakfast and the pool in our reviews. ...
8/10 Very Good! (2,117 reviews)
Friendly staff and housekeepers, tortoise keepers explained age and feeding schedule, loved the property!

Reviewed on Mar 1, 2026

Ibis Bay Beach Resort
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
$364 nightly
The price is $410 total per night from Mar 10 to Mar 11
$410 total
Mar 10 - Mar 11
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.2/10 Very Good! (1,964 reviews)
Friendly and well organized!

Reviewed on Mar 1, 2026

Blue Flamingo Resort Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Key West Hotels With Airport Transportation

DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
$417 nightly
The price is $470 total per night from Mar 8 to Mar 9
$470 total
Mar 8 - Mar 9
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.2/10 Very Good! (1,002 reviews)
Nice clean hotel. Smathers beach right down the road. Shuttle to Duval and the airport were very nice.

Reviewed on Feb 24, 2026

DoubleTree Resort by Hilton Grand Key - Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
$404 nightly
The price is $455 total per night from Mar 30 to Mar 31
$455 total
Mar 30 - Mar 31
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,323 reviews)
Over booked and even tho I reserved a room with a balcony almost 2 months ago they gave us a room w no view, no balcony and there were large ants in the bathroom. Only thing they gave us was a coupon for 2 free drinks, an “I’m sorry” and that’s it. We have stayed here multiple times but unfortunately ...

Reviewed on Feb 28, 2026

Hampton Inn Key West FL
Eden House

Eden House

3.5 out of 5
1015 Fleming St Key West FL
$430 nightly
The price is $483 total per night from Mar 4 to Mar 5
$483 total
Mar 4 - Mar 5
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, in-room massages, and a 24-hour front desk. Our guests praise the pool and the helpful staff in our reviews. ...
9/10 Wonderful! (1,005 reviews)
Clean, quiet nice inside and out. Pool area is excellent.

Reviewed on Feb 27, 2026

Eden House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Key West Hotels

Southwinds Motel

Southwinds Motel

2 out of 5
1321 Simonton Street Key West FL
$346 nightly
The price is $390 total per night from Mar 29 to Mar 30
$390 total
Mar 29 - Mar 30
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.8/10 Excellent! (1,285 reviews)
Room was small, shower pressure was poor and breakfast (compared with other hotels we stayed at) was terrible.

Reviewed on Mar 1, 2026

Southwinds Motel
Seashell Motel

Seashell Motel

1.5 out of 5
718 South Street Key West FL
$296 nightly
The price is $333 total per night from Mar 2 to Mar 3
$333 total
Mar 2 - Mar 3
Total with taxes and fees
Stay at this hostel in Key West. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8/10 Very Good! (1,003 reviews)
The rooms were very nice, updated and clean!!

Reviewed on Mar 1, 2026

Seashell Motel
Duval House

Duval House

3 out of 5
815 Duval St Key West FL
$401 nightly
The price is $448 total per night from Mar 8 to Mar 9
$448 total
Mar 8 - Mar 9
Total with taxes and fees
Stay at this B&B in Key West. Enjoy parking (surcharge), daily housekeeping, and a garden. Our guests praise the breakfast and the pool in our reviews. Popular ...
9.4/10 Exceptional! (1,003 reviews)
Clean rooms and great staff. Location is awesome

Reviewed on Mar 1, 2026

Duval House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Key West

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street Key West FL
$530 nightly
The price is $596 total per night from Mar 12 to Mar 13
$596 total
Mar 12 - Mar 13
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.8/10 Excellent! (3,099 reviews)
Staff were very friendly and accommodating. Room was very clean. I really enjoyed the property.

Reviewed on Mar 1, 2026

Southernmost Beach Resort and Guesthouses
Margaritaville Beach House Key West

Margaritaville Beach House Key West

4 out of 5
2001 South Roosevelt Blvd Key West FL
Book a stay at this beach hotel in Key West. Enjoy free parking, 2 restaurants, and breakfast (surcharge). Popular attractions Duval Street and Smathers Beach ...
8.4/10 Very Good! (1,000 reviews)

Families like: Outdoor pool, babysitting, close to beach, bicycle rentals

Travelers say...
Great visit

Reviewed on Feb 27, 2026

Get rates
Margaritaville Beach House Key West
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
$364 nightly
The price is $410 total per night from Mar 10 to Mar 11
$410 total
Mar 10 - Mar 11
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.2/10 Very Good! (1,964 reviews)

Families like: Outdoor pools, miniature golf, game room, bicycle rentals

Travelers say...
Friendly and well organized!

Reviewed on Mar 1, 2026

Blue Flamingo Resort Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MHT to EYW Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
MHT Address & GPS
Address:
One Airport Road
Manchester NH, 03103
United States
IATA Code:
MHT
Longitude:
-71.438439
Latitude:
42.927862
Time Zone:
America/New_York
EYW Address & GPS
Address:
3491 South Roosevelt Boulevard
Key West FL, 33040-5260
United States
IATA Code:
EYW
Longitude:
-81.75501
Latitude:
24.553574
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from Manchester-Boston Regional Airport (MHT) to Key West Intl. Airport (EYW)?
As you can't fly nonstop from Manchester-Boston Regional Airport (MHT) to Key West Intl. Airport (EYW) at the moment, a flight with just one stop is the next best thing. American Airlines, United Airlines and JetBlue Airways are popular airlines that service this route.
What is the shortest flight from Manchester Airport to Key West Intl. Airport (EYW)?
Getting from Manchester Airport to Key West Intl. Airport takes at least 4 hours and 58 minutes. Enjoy a tipple and get stuck into that book — this is your chance to sit back and unwind.
How many hours flight from MHT to Key West Intl. Airport?
It typically takes about 5 hours and 3 minutes to get from Manchester-Boston Regional Airport (MHT) to EYW. You'll be in the sky for a decent amount of time, so contemplate bringing plenty of entertainment, like an engrossing book or a podcast.
What airlines have the most flights from Manchester Airport to Key West Intl. Airport?
For now, you won't find any direct flights between MHT and EYW. However, you will find flights with at least one stop. There's always a positive side — use the time to get the blood flowing again or do a little souvenir shopping!

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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