Cheap flights from GSP to EYW (Greenville-Spartanburg Intl. to Key West Intl.)

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Cheap Flights from GSP to EYW starting at $289 One Way, $389 Round Trip

Prices starting at $389 for return flights and $289 for one-way flights to Key West Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Mon, Oct 12 - Fri, Oct 16
GSP
Greenville
EYW
Key West
$389 Roundtrip, found 5 days ago
$389
Roundtrip
found 5 days ago
Select American Airlines flight, departing Mon, Oct 12 from Greenville to Key West, returning Fri, Oct 16, priced at $389 found 5 days ago
Mon, Oct 12 - Fri, Oct 16
GSP
Greenville
EYW
Key West
$394 Roundtrip, found 5 days ago
$394
Roundtrip
found 5 days ago
Select American Airlines flight, departing Mon, Oct 12 from Greenville to Key West, returning Fri, Oct 16, priced at $394 found 5 days ago
Mon, Oct 12 - Fri, Oct 16
GSP
Greenville
EYW
Key West
$399 Roundtrip, found 5 days ago
$399
Roundtrip
found 5 days ago
Select American Airlines flight, departing Mon, Oct 12 from Greenville to Key West, returning Fri, Oct 16, priced at $399 found 5 days ago
Mon, Oct 12 - Fri, Oct 16
GSP
Greenville
EYW
Key West
$404 Roundtrip, found 5 days ago
$404
Roundtrip
found 5 days ago
Select American Airlines flight, departing Mon, Oct 12 from Greenville to Key West, returning Fri, Oct 16, priced at $404 found 5 days ago
Mon, Oct 12 - Fri, Oct 16
GSP
Greenville
EYW
Key West
$419 Roundtrip, found 5 days ago
$419
Roundtrip
found 5 days ago
Select Delta flight, departing Mon, Oct 12 from Greenville to Key West, returning Fri, Oct 16, priced at $419 found 5 days ago

Hotel Ideas near Key West Intl.

Airport Hotels near Key West Intl.

Hyatt Vacation Club at Windward Pointe, Key West

Hyatt Vacation Club at Windward Pointe, Key West

3.5 out of 5
3675 South Roosevelt Boulevard Key West FL
$200 nightly
The price is $225 total per night from Oct 4 to Oct 5
$225 total
Oct 4 - Oct 5
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, free parking, and a snack bar/deli. Our guests praise the pool and the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,278 reviews)
"This is the second year we have stayed here for our annual girl's trip. Everything was as great as it was last year. We plan on staying again next year."

Reviewed on Sep 17, 2026

Hyatt Vacation Club at Windward Pointe, Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
$134 nightly
The price is $151 total per night from Sep 22 to Sep 23
$151 total
Sep 22 - Sep 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,508 reviews)
"Clean room great staff"

Reviewed on Sep 17, 2026

Hampton Inn Key West FL
DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
$133 nightly
The price is $150 total per night from Sep 27 to Sep 28
$150 total
Sep 27 - Sep 28
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,098 reviews)
"Everything was ok"

Reviewed on Sep 18, 2026

DoubleTree Resort by Hilton Grand Key - Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Key West

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street Key West FL
$225 nightly
The price is $253 total per night from Sep 28 to Sep 29
$253 total
Sep 28 - Sep 29
Total with taxes and fees
Book a stay at this spa hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
Southernmost Beach Resort and Guesthouses
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
$160 nightly
The price is $180 total per night from Sep 20 to Sep 21
$180 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.6/10 Excellent! (2,677 reviews)
"The place was clean and staff were very friendly. The room was nicely appointed. The non-Tesla chargers were all broken which was disappointing but I was able to trickle charge. One elevator was also out but another one nearby was available and quick. Overall, very nice and I’d likely stay again ..."

Reviewed on Sep 18, 2026

Blue Flamingo Resort Key West
Margaritaville Beach House Key West

Margaritaville Beach House Key West

4 out of 5
2001 South Roosevelt Blvd Key West FL
$234 nightly
The price is $263 total per night from Oct 4 to Oct 5
$263 total
Oct 4 - Oct 5
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy breakfast (surcharge), a free airport shuttle, and room service. Our guests praise the pool and the restaurant ...
8.8/10 Excellent! (1,790 reviews)
"Great little place with very cute vibes and super friendly staff."

Reviewed on Sep 18, 2026

Margaritaville Beach House Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Key West Hotels With Airport Transportation

DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
$133 nightly
The price is $150 total per night from Sep 27 to Sep 28
$150 total
Sep 27 - Sep 28
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,098 reviews)
"Everything was ok"

Reviewed on Sep 18, 2026

DoubleTree Resort by Hilton Grand Key - Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
$134 nightly
The price is $151 total per night from Sep 22 to Sep 23
$151 total
Sep 22 - Sep 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,508 reviews)
"Clean room great staff"

Reviewed on Sep 17, 2026

Hampton Inn Key West FL
Eden House

Eden House

4 out of 5
1015 Fleming St Key West FL
$143 nightly
The price is $161 total per night from Sep 20 to Sep 21
$161 total
Sep 20 - Sep 21
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, in-room massages, and a 24-hour front desk. Our guests praise the pool and the helpful staff in our reviews. ...
9/10 Wonderful! (1,001 reviews)
"We love Eden house, this was our 5th stay and itcontinues to improve."

Reviewed on Sep 18, 2026

Eden House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Key West Hotels

Southwinds Motel

Southwinds Motel

2 out of 5
1321 Simonton Street Key West FL
$155 nightly
The price is $174 total per night from Sep 20 to Sep 21
$174 total
Sep 20 - Sep 21
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,381 reviews)
"Place was ok, Bar on premise and they had music, my room had ants(I told em and came and sprayed), pool was clean, the roosters were cool, They want 22.50 a day to park, waived it I'm handicap"

Reviewed on Sep 19, 2026

Southwinds Motel
Seashell Motel

Seashell Motel

1.5 out of 5
718 South Street Key West FL
$101 nightly
The price is $114 total per night from Sep 23 to Sep 24
$114 total
Sep 23 - Sep 24
Total with taxes and fees
Stay at this hostel in Key West. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Seashell Motel
Duval House

Duval House

3 out of 5
815 Duval St Key West FL
$105 nightly
The price is $115 total per night from Sep 27 to Sep 28
$115 total
Sep 27 - Sep 28
Total with taxes and fees
Stay at this B&B in Key West. Enjoy parking (surcharge), daily housekeeping, and a garden. Our guests praise the breakfast and the pool in our reviews. Popular ...
9.6/10 Exceptional! (1,095 reviews)
"A++++++++ highly recommended the Duval House was fantastic highly recommend. We can’t speak highly enough about our experience!"

Reviewed on Sep 18, 2026

Duval House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Key West

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street Key West FL
$225 nightly
The price is $253 total per night from Sep 28 to Sep 29
$253 total
Sep 28 - Sep 29
Total with taxes and fees
Book a stay at this spa hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
Southernmost Beach Resort and Guesthouses
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
$160 nightly
The price is $180 total per night from Sep 20 to Sep 21
$180 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.6/10 Excellent! (2,677 reviews)

Families like: Outdoor pools, playground, miniature golf, game room

Travelers say...
"The place was clean and staff were very friendly. The room was nicely appointed. The non-Tesla chargers were all broken which was disappointing but I was able to trickle charge. One elevator was also out but another one nearby was available and quick. Overall, very nice and I’d likely stay again ..."

Reviewed on Sep 18, 2026

Blue Flamingo Resort Key West
Hilton Key West Resort & Marina

Hilton Key West Resort & Marina

4 out of 5
5950 Peninsular Avenue Key West FL
$159 nightly
The price is $179 total per night from Sep 28 to Sep 29
$179 total
Sep 28 - Sep 29
Total with taxes and fees
Book a stay at this luxury hotel in Key West. Enjoy free WiFi, 6 outdoor pools, and a marina. Our guests praise the pool and the restaurant in our reviews. Popular ...
Hilton Key West Resort & Marina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

GSP to EYW Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
GSP Address & GPS
Address:
2000 GPS Drive, Suite 1
Greenville SC, 29651-9202
United States
IATA Code:
GSP
Longitude:
-82.217053
Latitude:
34.890569
Time Zone:
America/New_York
EYW Address & GPS
Address:
3491 South Roosevelt Boulevard
Key West FL, 33040-5260
United States
IATA Code:
EYW
Longitude:
-81.75501
Latitude:
24.553574
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from Roger Milliken Field to Key West Intl. Airport?
While you can't fly directly from GSP to EYW, there are plenty of carriers that service this route with only one stopover. Why not see if the dates available with American Airlines or Delta Air Lines work with your travel plans? If not, you could always try United Airlines.
What is the shortest flight from Greenville-Spartanburg Intl. Airport (GSP) to Key West Intl. Airport (EYW)?
Treat yourself to a miniature bottle of vino and settle into your seat with a fascinating book or movie. With the flight from Roger Milliken Field to EYW taking 4 hours and 54 minutes, you'll have plenty of time to kick back and enjoy the ride.
How many hours flight from Greenville-Spartanburg Intl. Airport (GSP) to EYW?
On average, it takes 4 hours and 57 minutes to jet from GSP to EYW. Breeze through the journey by watching TV shows and browsing a magazine or two. Alternatively, catch up on some Zs.
What airlines have the most flights from Roger Milliken Field to EYW?
Pick up a souvenir, grab a coffee, strike up a conversation with a stranger ... Airport stopovers don't have to irritating! If you're traveling between Greenville and Key West, there are no direct flights. Be prepared to make a stop somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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