Cheap flights from CMH to MSL (John Glenn Columbus Intl. to Northwest Alabama Regional)

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Cheap Flights from CMH to MSL starting at One Way, $997 Round Trip

Prices starting at $997 for return flights and for one-way flights to Northwest Alabama Regional were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Mon, Apr 27 - Wed, Apr 29
CMH
Columbus
MSL
Muscle Shoals
$997 Roundtrip, found 8 hours ago
$997
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Mon, Apr 27 from Columbus to Muscle Shoals, returning Wed, Apr 29, priced at $997 found 8 hours ago
Mon, Apr 27 - Wed, Apr 29
CMH
Columbus
MSL
Muscle Shoals
$1,001 Roundtrip, found 8 hours ago
$1,001
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Mon, Apr 27 from Columbus to Muscle Shoals, returning Wed, Apr 29, priced at $1,001 found 8 hours ago
Mon, Apr 27 - Wed, Apr 29
CMH
Columbus
MSL
Muscle Shoals
$1,002 Roundtrip, found 8 hours ago
$1,002
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Mon, Apr 27 from Columbus to Muscle Shoals, returning Wed, Apr 29, priced at $1,002 found 8 hours ago
Mon, Apr 27 - Wed, Apr 29
CMH
Columbus
MSL
Muscle Shoals
$1,035 Roundtrip, found 8 hours ago
$1,035
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Mon, Apr 27 from Columbus to Muscle Shoals, returning Wed, Apr 29, priced at $1,035 found 8 hours ago
Mon, Apr 27 - Wed, Apr 29
CMH
Columbus
MSL
Muscle Shoals
$1,095 Roundtrip, found 8 hours ago
$1,095
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Mon, Apr 27 from Columbus to Muscle Shoals, returning Wed, Apr 29, priced at $1,095 found 8 hours ago
Mon, Apr 27 - Wed, Apr 29
CMH
Columbus
MSL
Muscle Shoals
$1,099 Roundtrip, found 8 hours ago
$1,099
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Mon, Apr 27 from Columbus to Muscle Shoals, returning Wed, Apr 29, priced at $1,099 found 8 hours ago
Mon, Apr 27 - Wed, Apr 29
CMH
Columbus
MSL
Muscle Shoals
$1,100 Roundtrip, found 8 hours ago
$1,100
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Mon, Apr 27 from Columbus to Muscle Shoals, returning Wed, Apr 29, priced at $1,100 found 8 hours ago
Mon, Apr 27 - Wed, Apr 29
CMH
Columbus
MSL
Muscle Shoals
$1,111 Roundtrip, found 8 hours ago
$1,111
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Mon, Apr 27 from Columbus to Muscle Shoals, returning Wed, Apr 29, priced at $1,111 found 8 hours ago
Mon, Apr 27 - Wed, Apr 29
CMH
Columbus
MSL
Muscle Shoals
$1,116 Roundtrip, found 8 hours ago
$1,116
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Mon, Apr 27 from Columbus to Muscle Shoals, returning Wed, Apr 29, priced at $1,116 found 8 hours ago
Mon, Apr 27 - Wed, Apr 29
CMH
Columbus
MSL
Muscle Shoals
$1,117 Roundtrip, found 8 hours ago
$1,117
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Mon, Apr 27 from Columbus to Muscle Shoals, returning Wed, Apr 29, priced at $1,117 found 8 hours ago

Hotel Ideas near Northwest Alabama Regional

Airport Hotels near Northwest Alabama Regional

Days Inn by Wyndham Muscle Shoals Florence

Days Inn by Wyndham Muscle Shoals Florence

2 out of 5
2701 Woodward Ave Muscle Shoals AL
$71 nightly
The price is $79 total per night from Apr 16 to Apr 17
$79 total
Apr 16 - Apr 17
Total with taxes and fees
Stay at this hotel in Muscle Shoals. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.6/10 Excellent! (1,000 reviews)
The room was nice and clean. The breakfast wasn't great (coffee was lukewarm as was the food that was supposed to be hot, the waffle iron wasn't non stick so the waffle did not want to come off) but there were a few options so that part was fine. Just be aware with this location that it doesn't matter ...

Reviewed on Mar 30, 2026

Days Inn by Wyndham Muscle Shoals Florence
Clarion Inn Sheffield Muscle Shoals

Clarion Inn Sheffield Muscle Shoals

2.5 out of 5
4900 Hatch Blvd Sheffield AL
$77 nightly
The price is $86 total per night from Apr 21 to Apr 22
$86 total
Apr 21 - Apr 22
Total with taxes and fees
Book a stay at this business-friendly hotel in Sheffield. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.2/10 Good! (990 reviews)
Staff was excellent. Hotel was good as well. Would stay again

Reviewed on Mar 30, 2026

Clarion Inn Sheffield Muscle Shoals
3-bedroom w/pool and all the comforts of home in Muscle Shoals-recording capital

3-bedroom w/pool and all the comforts of home in Muscle Shoals-recording capital

Muscle Shoals AL
$265 nightly
The price is $291 total per night from Apr 6 to Apr 7
$291 total
Apr 6 - Apr 7
Total with taxes and fees
Stay at this vacation home in Muscle Shoals. Enjoy private pools, laundry facilities, and patios. Popular attractions Fame Recording Studios and Muscle Shoals ...
9.8/10 Exceptional! (48 reviews)
4 adults stayed for 4 nights in early March 2026. It was a very good experience overall. Very clean and nicely appointed. We did not cook or use the pool, so can't comment on that. Great covered deck that we used every day. The deck also had a gas grill. Excellent value compared to 2 hotel rooms. ...

Reviewed on Mar 10, 2026

3-bedroom w/pool and all the comforts of home in Muscle Shoals-recording capital
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Muscle Shoals

Days Inn by Wyndham Muscle Shoals Florence

Days Inn by Wyndham Muscle Shoals Florence

2 out of 5
2701 Woodward Ave Muscle Shoals AL
$71 nightly
The price is $79 total per night from Apr 16 to Apr 17
$79 total
Apr 16 - Apr 17
Total with taxes and fees
Stay at this hotel in Muscle Shoals. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.6/10 Excellent! (1,000 reviews)
The room was nice and clean. The breakfast wasn't great (coffee was lukewarm as was the food that was supposed to be hot, the waffle iron wasn't non stick so the waffle did not want to come off) but there were a few options so that part was fine. Just be aware with this location that it doesn't matter ...

Reviewed on Mar 30, 2026

Days Inn by Wyndham Muscle Shoals Florence
Stenson Hollow Lake Condo

Stenson Hollow Lake Condo

Muscle Shoals AL
$181 nightly
The price is $196 total per night from Apr 2 to Apr 3
$196 total
Apr 2 - Apr 3
Total with taxes and fees
Stay at this condo in Muscle Shoals. Enjoy free WiFi, patios, and cable/satellite TV service. Popular attractions River Heritage Park and Nature Trails Trailhead ...
Stenson Hollow Lake Condo
3-bedroom w/pool and all the comforts of home in Muscle Shoals-recording capital

3-bedroom w/pool and all the comforts of home in Muscle Shoals-recording capital

Muscle Shoals AL
$265 nightly
The price is $291 total per night from Apr 6 to Apr 7
$291 total
Apr 6 - Apr 7
Total with taxes and fees
Stay at this vacation home in Muscle Shoals. Enjoy private pools, laundry facilities, and patios. Popular attractions Fame Recording Studios and Muscle Shoals ...
9.8/10 Exceptional! (48 reviews)
4 adults stayed for 4 nights in early March 2026. It was a very good experience overall. Very clean and nicely appointed. We did not cook or use the pool, so can't comment on that. Great covered deck that we used every day. The deck also had a gas grill. Excellent value compared to 2 hotel rooms. ...

Reviewed on Mar 10, 2026

3-bedroom w/pool and all the comforts of home in Muscle Shoals-recording capital
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Muscle Shoals Hotels

Days Inn by Wyndham Muscle Shoals Florence

Days Inn by Wyndham Muscle Shoals Florence

2 out of 5
2701 Woodward Ave Muscle Shoals AL
$71 nightly
The price is $79 total per night from Apr 16 to Apr 17
$79 total
Apr 16 - Apr 17
Total with taxes and fees
Stay at this hotel in Muscle Shoals. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.6/10 Excellent! (1,000 reviews)
The room was nice and clean. The breakfast wasn't great (coffee was lukewarm as was the food that was supposed to be hot, the waffle iron wasn't non stick so the waffle did not want to come off) but there were a few options so that part was fine. Just be aware with this location that it doesn't matter ...

Reviewed on Mar 30, 2026

Days Inn by Wyndham Muscle Shoals Florence
Red Roof Inn Muscle Shoals

Red Roof Inn Muscle Shoals

2.5 out of 5
2807 Woodward Ave Muscle Shoals AL
$75 nightly
The price is $83 total per night from Apr 2 to Apr 3
$83 total
Apr 2 - Apr 3
Total with taxes and fees
Book a stay at this business-friendly hotel in Muscle Shoals. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Fame Recording Studios and ...
6.8/10 (308 reviews)
Staff and property was amazing

Reviewed on Feb 13, 2026

Red Roof Inn Muscle Shoals
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Muscle Shoals

Red Roof Inn Muscle Shoals

Red Roof Inn Muscle Shoals

2.5 out of 5
2807 Woodward Ave Muscle Shoals AL
$75 nightly
The price is $83 total per night from Apr 2 to Apr 3
$83 total
Apr 2 - Apr 3
Total with taxes and fees
Book a stay at this business-friendly hotel in Muscle Shoals. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Fame Recording Studios and ...
6.8/10 (308 reviews)
Staff and property was amazing

Reviewed on Feb 13, 2026

Red Roof Inn Muscle Shoals
Days Inn by Wyndham Muscle Shoals Florence

Days Inn by Wyndham Muscle Shoals Florence

2 out of 5
2701 Woodward Ave Muscle Shoals AL
$71 nightly
The price is $79 total per night from Apr 16 to Apr 17
$79 total
Apr 16 - Apr 17
Total with taxes and fees
Stay at this hotel in Muscle Shoals. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.6/10 Excellent! (1,000 reviews)
The room was nice and clean. The breakfast wasn't great (coffee was lukewarm as was the food that was supposed to be hot, the waffle iron wasn't non stick so the waffle did not want to come off) but there were a few options so that part was fine. Just be aware with this location that it doesn't matter ...

Reviewed on Mar 30, 2026

Days Inn by Wyndham Muscle Shoals Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

CMH to MSL Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date

Frequently asked questions

What airlines have the most flights from John Glenn Columbus Intl. Airport (CMH) to MSL?
At the moment, there are no airlines that offer direct flights from CMH to Northwest Alabama Regional Airport (MSL). But never fear. There are lots of single or multi-stop flights available.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.