Cheap flights from CLE to TYS (Hopkins Intl. to McGhee Tyson)

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Cheap Flights from CLE to TYS starting at $130 One Way, $174 Round Trip

Prices starting at $174 for return flights and $130 for one-way flights to McGhee Tyson were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Hotel Ideas near McGhee Tyson

Airport Hotels near McGhee Tyson

La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road Alcoa TN
$85 nightly
The price is $100 total per night from Feb 22 to Feb 23
$100 total
Feb 22 - Feb 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,759 reviews)
Room was nice, and check in easy and quick with lovely staff. However, checking-out was time-consuming and airport shuttle times did not make sense.

Reviewed on Feb 20, 2026

La Quinta Inn & Suites by Wyndham Knoxville Airport
Hilton Knoxville Airport

Hilton Knoxville Airport

3.5 out of 5
2001 Alcoa Hwy Alcoa TN
$123 nightly
The price is $141 total per night from Feb 28 to Mar 1
$141 total
Feb 28 - Mar 1
Total with taxes and fees
Book a stay at this family-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,008 reviews)
Really enjoyed my stay. The bathroom door didn’t shut and the in house restaurant was slow but those were the only downfalls!

Reviewed on Feb 20, 2026

Hilton Knoxville Airport
Comfort Suites Knoxville Airport

Comfort Suites Knoxville Airport

2.5 out of 5
140 Cusick Rd Alcoa TN
$74 nightly
The price is $88 total per night from Feb 26 to Feb 27
$88 total
Feb 26 - Feb 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.8/10 Good! (767 reviews)
Airport shuttle was late causing us to almost miss our flight. Had to beg to skip the line to make it.

Reviewed on Feb 15, 2026

Comfort Suites Knoxville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Knoxville

La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road Alcoa TN
$85 nightly
The price is $100 total per night from Feb 22 to Feb 23
$100 total
Feb 22 - Feb 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,759 reviews)
Room was nice, and check in easy and quick with lovely staff. However, checking-out was time-consuming and airport shuttle times did not make sense.

Reviewed on Feb 20, 2026

La Quinta Inn & Suites by Wyndham Knoxville Airport
Hilton Knoxville Airport

Hilton Knoxville Airport

3.5 out of 5
2001 Alcoa Hwy Alcoa TN
$123 nightly
The price is $141 total per night from Feb 28 to Mar 1
$141 total
Feb 28 - Mar 1
Total with taxes and fees
Book a stay at this family-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,008 reviews)
Really enjoyed my stay. The bathroom door didn’t shut and the in house restaurant was slow but those were the only downfalls!

Reviewed on Feb 20, 2026

Hilton Knoxville Airport
Mainstay Suites Knoxville Airport

Mainstay Suites Knoxville Airport

2.5 out of 5
361 Fountain View Cir Alcoa TN
$76 nightly
The price is $90 total per night from Feb 21 to Feb 22
$90 total
Feb 21 - Feb 22
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.8/10 Good! (703 reviews)
Staff is wonderful

Reviewed on Feb 20, 2026

Mainstay Suites Knoxville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Knoxville Hotels With Airport Transportation

La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road Alcoa TN
$85 nightly
The price is $100 total per night from Feb 22 to Feb 23
$100 total
Feb 22 - Feb 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,759 reviews)
Room was nice, and check in easy and quick with lovely staff. However, checking-out was time-consuming and airport shuttle times did not make sense.

Reviewed on Feb 20, 2026

La Quinta Inn & Suites by Wyndham Knoxville Airport
USA Inn

USA Inn

3 out of 5
Alcoa Hwy, 2962 Alcoa TN
$56 nightly
The price is $66 total per night from Feb 25 to Feb 26
$66 total
Feb 25 - Feb 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Meigs Falls and Fort Loudoun ...
5/10 (714 reviews)
Won’t be back

Reviewed on Oct 12, 2025

USA Inn
Best Western Knoxville Airport/Alcoa

Best Western Knoxville Airport/Alcoa

2.5 out of 5
162 Cusick Rd Alcoa TN
$69 nightly
The price is $82 total per night from Feb 27 to Feb 28
$82 total
Feb 27 - Feb 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,003 reviews)
We have enjoyed staying here both times. Room was clean and the staff was helpful.

Reviewed on Feb 19, 2026

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Knoxville Hotels

USA Inn

USA Inn

3 out of 5
Alcoa Hwy, 2962 Alcoa TN
$56 nightly
The price is $66 total per night from Feb 25 to Feb 26
$66 total
Feb 25 - Feb 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Meigs Falls and Fort Loudoun ...
5/10 (714 reviews)
Won’t be back

Reviewed on Oct 12, 2025

USA Inn
Candlewood Suites Knoxville Airport-Alcoa by IHG

Candlewood Suites Knoxville Airport-Alcoa by IHG

2.5 out of 5
176 Cusick Road Alcoa TN
$67 nightly
The price is $80 total per night from Feb 23 to Feb 24
$80 total
Feb 23 - Feb 24
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, an outdoor pool, and a free airport shuttle. Popular attractions Meigs Falls and Palace ...
8.4/10 Very Good! (622 reviews)
The only, and I do mean only, thing remotely okay about this place is it's close to the airport. That is realistically the nicest thing that can be said for my stay there. I will NEVER stay there again!!

Reviewed on Feb 14, 2026

Candlewood Suites Knoxville Airport-Alcoa by IHG
Best Western Knoxville Airport/Alcoa

Best Western Knoxville Airport/Alcoa

2.5 out of 5
162 Cusick Rd Alcoa TN
$69 nightly
The price is $82 total per night from Feb 27 to Feb 28
$82 total
Feb 27 - Feb 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,003 reviews)
We have enjoyed staying here both times. Room was clean and the staff was helpful.

Reviewed on Feb 19, 2026

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Knoxville

Comfort Suites Knoxville Airport

Comfort Suites Knoxville Airport

2.5 out of 5
140 Cusick Rd Alcoa TN
$74 nightly
The price is $88 total per night from Feb 26 to Feb 27
$88 total
Feb 26 - Feb 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.8/10 Good! (767 reviews)
Airport shuttle was late causing us to almost miss our flight. Had to beg to skip the line to make it.

Reviewed on Feb 15, 2026

Comfort Suites Knoxville Airport
Best Western Knoxville Airport/Alcoa

Best Western Knoxville Airport/Alcoa

2.5 out of 5
162 Cusick Rd Alcoa TN
$69 nightly
The price is $82 total per night from Feb 27 to Feb 28
$82 total
Feb 27 - Feb 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,003 reviews)
We have enjoyed staying here both times. Room was clean and the staff was helpful.

Reviewed on Feb 19, 2026

Best Western Knoxville Airport/Alcoa
La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road Alcoa TN
$85 nightly
The price is $100 total per night from Feb 22 to Feb 23
$100 total
Feb 22 - Feb 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,759 reviews)
Room was nice, and check in easy and quick with lovely staff. However, checking-out was time-consuming and airport shuttle times did not make sense.

Reviewed on Feb 20, 2026

La Quinta Inn & Suites by Wyndham Knoxville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

CLE to TYS Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date

Frequently asked questions

Are there non-stop flights from Cleveland Hopkins Intl. Airport to Knoxville Airport?
If you're about to fly from Hopkins Intl. Airport (CLE) to Knoxville Airport, you'll need to change planes. American Airlines, Delta Air Lines and United Airlines are airlines that operate on this route with only one stopover. Use the time to stretch out your legs and try out a local delicacy or two.
What is the shortest flight from CLE to Knoxville Airport?
Order a miniature bottle of vino and get comfortable in your seat with a fascinating novel or movie. With the flight from Cleveland to Knoxville taking 4 hours and 6 minutes, there's plenty of time to kick back and enjoy the experience.
How many hours flight from CLE to TYS?
Usually, the flight from CLE to McGhee Tyson Airport (TYS) takes 4 hours and 13 minutes. If you would like to be as comfortable as you can, think about upgrading your seat using miles or cash.
What airlines have the most flights from Hopkins Intl. Airport (CLE) to Knoxville Airport?
At the moment, you can't fly nonstop from Cleveland to Knoxville. However, you will be able to lock in a flight with at least one stop. There's always a positive side — use the time to stretch your tired legs or grab a decent coffee!

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.