Cheap flights from BUF to EYW (Buffalo Niagara Intl. to Key West Intl.)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Cheap Flights from BUF to EYW starting at $199 One Way, $269 Round Trip

Prices starting at $269 for return flights and $199 for one-way flights to Key West Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Feb 21 - Thu, Feb 26
BUF
Buffalo
EYW
Key West
$269 Roundtrip, found 17 hours ago
$269
Roundtrip
found 17 hours ago
Select Delta flight, departing Sat, Feb 21 from Buffalo to Key West, returning Thu, Feb 26, priced at $269 found 17 hours ago
Fri, Jan 9 - Tue, Jan 13
BUF
Buffalo
EYW
Key West
$269 Roundtrip, found 2 hours ago
$269
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Fri, Jan 9 from Buffalo to Key West, returning Tue, Jan 13, priced at $269 found 2 hours ago
Sat, Nov 15 - Tue, Nov 18
BUF
Buffalo
EYW
Key West
$273 Roundtrip, found 5 days ago
$273
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, Nov 15 from Buffalo to Key West, returning Tue, Nov 18, priced at $273 found 5 days ago
Thu, Feb 19 - Thu, Feb 26
BUF
Buffalo
EYW
Key West
$274 Roundtrip, found 17 hours ago
$274
Roundtrip
found 17 hours ago
Select Delta flight, departing Thu, Feb 19 from Buffalo to Key West, returning Thu, Feb 26, priced at $274 found 17 hours ago
Sat, Nov 15 - Tue, Nov 18
BUF
Buffalo
EYW
Key West
$278 Roundtrip, found 5 days ago
$278
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sat, Nov 15 from Buffalo to Key West, returning Tue, Nov 18, priced at $278 found 5 days ago

Hotel Ideas near Key West Intl.

Airport Hotels near Key West Intl.

Hyatt Vacation Club at Windward Pointe, Key West

Hyatt Vacation Club at Windward Pointe, Key West

3.5 out of 5
3675 South Roosevelt Boulevard, Key West, FL
$303 nightly
The price is $340 total per night from Nov 18 to Nov 19
$340 total
Nov 18 - Nov 19
Total with taxes and fees
Stay at this 3.5-star eco-certified hotel in Key West. Enjoy free WiFi, free parking, and a snack bar/deli. Our guests praise the pool and the helpful staff ...
9.4/10 Exceptional! (1,030 reviews)
Was great!

Reviewed on Oct 24, 2025

Hyatt Vacation Club at Windward Pointe, Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd, Key West, FL
$154 nightly
The price is $173 total per night from Oct 28 to Oct 29
$173 total
Oct 28 - Oct 29
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,249 reviews)
Everything was perfect and the staff was the most professional and friendly we ever had

Reviewed on Oct 21, 2025

Hampton Inn Key West FL
DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd, Key West, FL
$159 nightly
The price is $179 total per night from Oct 28 to Oct 29
$179 total
Oct 28 - Oct 29
Total with taxes and fees
Stay at this 4-star business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8/10 Very Good! (1,006 reviews)
I love the renovation! It is so much more inviting!

Reviewed on Oct 24, 2025

DoubleTree Resort by Hilton Grand Key - Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Key West

Oceans Edge Key West Resort, Hotel & Marina

Oceans Edge Key West Resort, Hotel & Marina

4 out of 5
5950 Peninsular Avenue, Key West, FL
$197 nightly
The price is $222 total per night from Nov 17 to Nov 18
$222 total
Nov 17 - Nov 18
Total with taxes and fees
Stay at this 4-star luxury hotel in Key West. Enjoy free WiFi, 6 outdoor pools, and a marina. Our guests praise the pool and the restaurant in our reviews. Popular ...
8.8/10 Excellent! (1,726 reviews)
Beautiful setting - great water views. Room was clean and comfortable - pools were great.

Reviewed on Oct 24, 2025

Oceans Edge Key West Resort, Hotel & Marina
Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street, Key West, FL
$211 nightly
The price is $238 total per night from Oct 30 to Oct 31
$238 total
Oct 30 - Oct 31
Total with taxes and fees
Stay at this 4-star beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the bar in our reviews. ...
8.6/10 Excellent! (2,817 reviews)
Beach view excellent. Dining and drink options wonderful

Reviewed on Oct 24, 2025

Southernmost Beach Resort and Guesthouses
Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa

4 out of 5
601 Front St, Key West, FL
$262 nightly
The price is $295 total per night from Oct 28 to Oct 29
$295 total
Oct 28 - Oct 29
Total with taxes and fees
Book a stay at this beach resort in Key West. Enjoy free WiFi, a full-service spa, and a marina. Our guests praise the pool and the bar in our reviews. Popular ...
8.8/10 Excellent! (1,014 reviews)
The hotel is right on the beach, had all the amenities and walking distance from Duvall street and Mallory square. Sunsets were beautiful

Reviewed on Oct 25, 2025

Hyatt Centric Key West Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Key West Hotels With Airport Transportation

DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd, Key West, FL
$159 nightly
The price is $179 total per night from Oct 28 to Oct 29
$179 total
Oct 28 - Oct 29
Total with taxes and fees
Stay at this 4-star business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8/10 Very Good! (1,006 reviews)
I love the renovation! It is so much more inviting!

Reviewed on Oct 24, 2025

DoubleTree Resort by Hilton Grand Key - Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd, Key West, FL
$154 nightly
The price is $173 total per night from Oct 28 to Oct 29
$173 total
Oct 28 - Oct 29
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,249 reviews)
Everything was perfect and the staff was the most professional and friendly we ever had

Reviewed on Oct 21, 2025

Hampton Inn Key West FL
Eden House

Eden House

3.5 out of 5
1015 Fleming St, Key West, FL
$223 nightly
The price is $251 total per night from Oct 28 to Oct 29
$251 total
Oct 28 - Oct 29
Total with taxes and fees
Stay at this 3.5-star hotel in Key West. Enjoy free WiFi, in-room massages, and a 24-hour front desk. Our guests praise the pool and the helpful staff in our ...
9/10 Wonderful! (1,002 reviews)
The grounds and buildings were very well upkept but had the wonderful old feel. I loved the wooden banisters and all the seating around the property. I will be staying here again on future visits. AMAZING STAY!!!

Reviewed on Oct 22, 2025

Eden House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Key West Hotels

Southwinds Motel

Southwinds Motel

2 out of 5
1321 Simonton Street, Key West, FL
$162 nightly
The price is $183 total per night from Oct 28 to Oct 29
$183 total
Oct 28 - Oct 29
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and a 24-hour front desk. Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,211 reviews)
There was an issue with the location and facilities of the room but they were resolved with no extra effort

Reviewed on Oct 21, 2025

Southwinds Motel
Seashell Motel

Seashell Motel

1.5 out of 5
718 South Street, Key West, FL
$109 nightly
The price is $123 total per night from Oct 28 to Oct 29
$123 total
Oct 28 - Oct 29
Total with taxes and fees
Stay at this hostel in Key West. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7.8/10 Good! (1,007 reviews)
Don’t let the construction on the outside fool you, the rooms are nice. My room was recently redone to include a brand new tile bathroom that is nicer than mine at home. Fresh paint, new lg flat screen tv, comfy beds, new flooring, and plenty of space to move around. The pool was under construction ...

Reviewed on Oct 18, 2025

Seashell Motel
Duval House

Duval House

3 out of 5
815 Duval St, Key West, FL
$131 nightly
The price is $144 total per night from Oct 28 to Oct 29
$144 total
Oct 28 - Oct 29
Total with taxes and fees
Stay at this 3-star B&B in Key West. Enjoy parking (surcharge), daily housekeeping, and a garden. Our guests praise the breakfast and the pool in our reviews. ...
9.4/10 Exceptional! (1,027 reviews)
I like the Key West style of the property. The furniture style is classic Key West. Beds were comfortable. Some of the sheets felt like nylon, kinda noisy when you move. The window unit a/c was very noisy. It kept going on and off every 6 minutes at different temp settings. The bathroom was not well ...

Reviewed on Oct 20, 2025

Duval House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Key West

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street, Key West, FL
$211 nightly
The price is $238 total per night from Oct 30 to Oct 31
$238 total
Oct 30 - Oct 31
Total with taxes and fees
Stay at this 4-star beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the bar in our reviews. ...
8.6/10 Excellent! (2,817 reviews)
Beach view excellent. Dining and drink options wonderful

Reviewed on Oct 24, 2025

Southernmost Beach Resort and Guesthouses
Margaritaville Beach House Key West

Margaritaville Beach House Key West

4 out of 5
2001 South Roosevelt Blvd, Key West, FL
Stay at this 4-star beach hotel in Key West. Enjoy free parking, 2 restaurants, and breakfast (surcharge). Popular attractions Duval Street and Smathers Beach ...
8.2/10 Very Good! (1,000 reviews)

Families like: Outdoor pool, babysitting, close to beach, bicycle rentals

Travelers say...
Stayed here many times. Easy in and out, plenty of parking. Great friendly staff

Reviewed on Sep 1, 2025

Get rates
Margaritaville Beach House Key West
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard, Key West, FL
$139 nightly
The price is $157 total per night from Oct 28 to Oct 29
$157 total
Oct 28 - Oct 29
Total with taxes and fees
Stay at this 4-star family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
7.8/10 Good! (1,629 reviews)

Families like: Outdoor pools, miniature golf, game room, bicycle rentals

Travelers say...
All great!

Reviewed on Oct 24, 2025

Blue Flamingo Resort Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

BUF to EYW Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
BUF Address & GPS
Address:
Genesee Street
Buffalo NY, 14225
United States
IATA Code:
BUF
Longitude:
-78.731804
Latitude:
42.933828
Time Zone:
America/New_York
EYW Address & GPS
Address:
3491 South Roosevelt Boulevard
Key West FL, 33040-5260
United States
IATA Code:
EYW
Longitude:
-81.75501
Latitude:
24.553574
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from BUF to EYW?
While you won't be able to fly direct from Buffalo Niagara International Airport to EYW, there are several companies that service this route with just a single stopover. Why not see if the dates available with American Airlines or United Airlines match your travel plans? If not, take a look at Delta Air Lines.
What is the shortest flight from BUF to Key West Intl. Airport (EYW)?
Make the most of the opportunity to chill out on the flight from Buffalo to Key West. The shortest flight time from BUF to EYW is 4 hours and 51 minutes, which gives you plenty of time to enjoy a drink or lose yourself in a good book.
How many hours flight from Buffalo Niagara Intl. Airport (BUF) to Key West Intl. Airport?
Get nice and comfortable, because the average plane trip from Buffalo Niagara Intl. Airport (BUF) to Key West Intl. Airport is 4 hours and 55 minutes. Watch a few movies, finish that book … You'll have more than enough time to sit back and enjoy the ride.
What airlines have the most flights from BUF to Key West Intl. Airport (EYW)?
Currently, there are no airlines that have direct flights between Buffalo Niagara International Airport and Key West Intl. Airport. But there's a silver lining. There are several single or multi-stop flights available.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

More to Explore