$251 Cheap flight deals from Quito (UIO) to Panama City (PTY)

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This Weekend's Flight Deals from Quito to Panama City

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Dec 27 - Sun, Jan 11
UIO
Mariscal Sucre Intl.
PTY
Tocumen Intl.
$567 Roundtrip, found 23 hours ago
$567
Roundtrip
found 23 hours ago
Select avianca flight, departing Sat, Dec 27 from Mariscal Sucre Intl. to Tocumen Intl., returning Sun, Jan 11, priced at $567 found 23 hours ago

Airfares from $251 One Way, $462 Round Trip from Quito to Panama City

Prices starting at $462 for return flights and $251 for one-way flights to Panama City were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Jan 22 - Sat, Jan 24
UIO
Quito
PTY
Panama City
$462 Roundtrip, just found
$462
Roundtrip
just found
Select Copa flight, departing Thu, Jan 22 from Quito to Panama City, returning Sat, Jan 24, priced at $462 just found
Thu, Jan 22 - Sat, Jan 24
UIO
Quito
PTY
Panama City
$474 Roundtrip, just found
$474
Roundtrip
just found
Select Copa flight, departing Thu, Jan 22 from Quito to Panama City, returning Sat, Jan 24, priced at $474 just found
Thu, Jan 22 - Sat, Jan 24
UIO
Quito
PTY
Panama City
$486 Roundtrip, just found
$486
Roundtrip
just found
Select Copa flight, departing Thu, Jan 22 from Quito to Panama City, returning Sat, Jan 24, priced at $486 just found
Thu, Apr 23 - Sun, Apr 26
UIO
Quito
PTY
Panama City
$487 Roundtrip, found 1 day ago
$487
Roundtrip
found 1 day ago
Select avianca flight, departing Thu, Apr 23 from Quito to Panama City, returning Sun, Apr 26, priced at $487 found 1 day ago
Thu, Apr 23 - Sun, Apr 26
UIO
Quito
PTY
Panama City
$493 Roundtrip, found 1 day ago
$493
Roundtrip
found 1 day ago
Select avianca flight, departing Thu, Apr 23 from Quito to Panama City, returning Sun, Apr 26, priced at $493 found 1 day ago

Panama City economy flight packages

Price found within the past 48 hours. Click for updated prices.
Mahogany Suites
2.0-star property

Mahogany Suites

10/10 Exceptional! (1 review)

Feb 7 - Feb 14

7 night stay

Quito (UIO) to Panama City (PTY)

Avianca • Non-stop roundtrip • Coach
Price was $1,279, price is now $782 per person
$782
per person
found 1 day ago
Central Hotel Panama Casco Viejo
4.0-star property

Central Hotel Panama Casco Viejo

9/10 Wonderful! (1,002 reviews)

Feb 7 - Feb 14

7 night stay

Quito (UIO) to Panama City (PTY)

Avianca • Non-stop roundtrip • Coach
Save 100% on your flight
Price was $2,789, price is now $1,642 per person
$1,642
per person
found 1 day ago
Kimberly at the Front Desk was wonderful!

Reviewed on Jun 8, 2025

Dreams Playa Bonita Panama - All Inclusive
4.0-star property

Dreams Playa Bonita Panama - All Inclusive

7.4/10 Good! (1,002 reviews)

Feb 7 - Feb 14

7 night stay

Quito (UIO) to Panama City (PTY)

Avianca • Non-stop roundtrip • Coach
Save 100% on your flight
Price was $2,947, price is now $2,108 per person
$2,108
per person
found 1 day ago
Several restaurants onsite. Beach was beautiful! Lots of entertainment!

Reviewed on Nov 10, 2025

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More About Flying To Panama City from Quito

Route Information for Flights from Quito to Panama City

Origin Airport IATA Code
UIO
Destination Airport IATA Code
PTY
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Quito to Panama City

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Frequently asked questions

Are there non-stop flights from Quito to Panama City?
Yep, Copa Airlines flies straight from Quito to Panama City, so you'll be starting your awesome adventure before you know it.
What is the shortest flight from Quito to Panama City?
If conditions are good and all goes as scheduled, you could be disembarking at PTY from Quito International Airport in just 1 hour and 46 minutes. With such a brief flight time, think about taking just hand luggage.
What airlines fly from Quito to Panama City most frequently?
Copa Airlines has the most flights along this route. This trusted carrier operates 117 flights from UIO to Panama City (PTY-Tocumen Intl.) each month.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.