Shop travel

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Sat, Mar 14 - Sun, Mar 15

SDF

Louisville Intl.

DTW

Detroit Metropolitan Wayne County

$723

Roundtrip

found 1 day ago

Sun, Mar 15 - Thu, Mar 19

LEX

Blue Grass

DTW

Detroit Metropolitan Wayne County

$791

Roundtrip

found 1 day ago

Tue, Apr 21 - Wed, Apr 22

SDF

Louisville

DTW

Detroit

$183

Roundtrip

found 5 days ago

Tue, Apr 21 - Wed, Apr 22

SDF

Louisville

DTW

Detroit

$183

Roundtrip

found 5 days ago

Tue, Apr 21 - Wed, Apr 22

SDF

Louisville

DTW

Detroit

$233

Roundtrip

found 5 days ago

Mon, Apr 6 - Wed, Apr 8

SDF

Louisville

DTW

Detroit

$234

Roundtrip

found 5 days ago

Tue, Apr 21 - Wed, Apr 22

SDF

Louisville

DTW

Detroit

$246

Roundtrip

found 5 days ago

Price found within the past 48 hours. Click for updated prices.

3.0-star property

Hotel Houze Detroit Downtown

7.8/10 Good! (136 reviews)

Apr 20 - Apr 22

2 night stay

Louisville (SDF) to Detroit (DTW)

Delta • Coach

Detroit (DTW) to Louisville (SDF)

Southwest Airlines • Coach

$505

per person

found 1 day ago

4.0-star property

Saint John's Resort

9.6/10 Exceptional! (1,006 reviews)

Apr 20 - Apr 22

2 night stay

Louisville (SDF) to Detroit (DTW)

Delta • Coach

Detroit (DTW) to Louisville (SDF)

Southwest Airlines • Coach

$744

per person

found 1 day ago

Excellent Stay! Exceptionally Clean and Beautiful Resort! The Christmas decorations looked amazing! The art-work within the hallways were such a treat to view. The Chapel is beautiful and peaceful. The resort has very friendly, helpful and knowledgeable staff, especially the two front desk ladies with similar names, Stephanie and Steph :-) Thank-you for an absolutely wonderful stay!

Reviewed on Jan 5, 2026

4.0-star property

Hollywood Casino at Greektown

8.6/10 Excellent! (5,037 reviews)

Apr 20 - Apr 22

2 night stay

Louisville (SDF) to Detroit (DTW)

Delta • Coach

Detroit (DTW) to Louisville (SDF)

Southwest Airlines • Coach

$584

per person

found 1 day ago

Our stay was average overall. There was no daily housekeeping, and when we requested towels from the front desk, it took about an hour for them to arrive. Several elevators were out of service, and after waiting nearly 30 minutes, we decided to take the stairs from the 20th floor. Unfortunately, when we reached the 14th floor, we encountered a sign warning that continuing further would trigger an alarm. When we tried to return to the elevators, we discovered we were locked in the stairwell. Thankfully, we had cell service and were able to call the front desk, who sent security to let us out.

Reviewed on Oct 14, 2025

Don't see what you're looking for?

See all available trips from Louisville to Detroit

View all trips

Frequently asked questions

Are there non-stop flights from Louisville to Detroit?

Delta will fly you nonstop from Lexington, KY (LEX-Blue Grass) to Detroit, MI (DTW-Detroit Metropolitan Wayne County), which means you won't have to stress about switching planes or missing your connection on this route.

What is the shortest flight from Louisville to Detroit?

It can zip by in as little as 2 hours and 20 minutes. If you strongly believe your vacation hours should be spent 'vacationing' instead of flying, you'll enjoy the journey from Louisville to Detroit.

What airlines fly from Louisville to Detroit most frequently?

Delta offers the most services from Louisville to Detroit, with 117 flights each month.

What is the cheapest day of the week to fly?

Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.

What is the cheapest month to fly?

We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.