$225 Cheap flight deals from Quad Cities (MLI) to Charleston (CHS)

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This Weekend's Flight Deals from Quad Cities to Charleston

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Jun 7 - Mon, Jun 16
MLI
Quad City Intl.
CHS
Charleston Intl.
$289 Roundtrip, found 2 days ago
$289
Roundtrip
found 2 days ago
Select Delta flight, departing Sat, Jun 7 from Quad City Intl. to Charleston Intl., returning Mon, Jun 16, priced at $289 found 2 days ago

Airfares from $225 One Way, $249 Round Trip from Quad Cities to Charleston

Prices starting at $249 for return flights and $225 for one-way flights to Charleston were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Jul 12 - Mon, Jul 14
MLI
Moline
CHS
Charleston
$249 Roundtrip, found 3 days ago
$249
Roundtrip
found 3 days ago
Select Delta flight, departing Sat, Jul 12 from Moline to Charleston, returning Mon, Jul 14, priced at $249 found 3 days ago
Wed, Jul 9 - Wed, Jul 16
MLI
Moline
CHS
Charleston
$249 Roundtrip, found 3 days ago
$249
Roundtrip
found 3 days ago
Select United flight, departing Wed, Jul 9 from Moline to Charleston, returning Wed, Jul 16, priced at $249 found 3 days ago
Tue, Jul 8 - Mon, Jul 14
MLI
Moline
CHS
Charleston
$253 Roundtrip, found 3 days ago
$253
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Jul 8 from Moline to Charleston, returning Mon, Jul 14, priced at $253 found 3 days ago
Wed, Jul 9 - Wed, Jul 16
MLI
Moline
CHS
Charleston
$260 Roundtrip, found 3 days ago
$260
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Jul 9 from Moline to Charleston, returning Wed, Jul 16, priced at $260 found 3 days ago
Wed, Jun 11 - Mon, Jun 16
MLI
Moline
CHS
Charleston
$263 Roundtrip, found 2 days ago
$263
Roundtrip
found 2 days ago
Select Delta flight, departing Wed, Jun 11 from Moline to Charleston, returning Mon, Jun 16, priced at $263 found 2 days ago

Charleston economy flight packages

Price found within the past 48 hours. Click for updated prices.
Crowne Plaza Charleston Airport - Conv Ctr by IHG
3.5-star property

Crowne Plaza Charleston Airport - Conv Ctr by IHG

8.6/10 Excellent! (1,028 reviews)

Jul 14 - Jul 20

6 night stay

Moline (MLI) to Charleston (CHS)

Delta • Non-stop roundtrip • Coach
per person
found 1 day ago
Beds were great, staff was very helpful, shuttle ride to airport was quick and easy

Reviewed on May 8, 2025

Emeline
4.0-star property

Emeline

9.2/10 Wonderful! (1,594 reviews)

Jul 14 - Jul 20

6 night stay

Moline (MLI) to Charleston (CHS)

Delta • Non-stop roundtrip • Coach
Save 100% on your flight
per person
found 1 day ago
Perfectly situated hotel, walking distance to all the best restaurants and shops. Hotel was clean/quiet. Courtyard is beautiful. What else can we ask for. Will definitely come back.

Reviewed on May 6, 2025

The Vendue
4.0-star property

The Vendue

9.4/10 Exceptional! (541 reviews)

Jul 14 - Jul 20

6 night stay

Moline (MLI) to Charleston (CHS)

Delta • Non-stop roundtrip • Coach
per person
found 1 day ago
Beautiful property, great location.

Reviewed on Mar 31, 2025

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More About Flying To Charleston from Quad Cities

Route Information for Flights from Quad Cities to Charleston

Origin Airport IATA Code
MLI
Destination Airport IATA Code
CHS
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Quad Cities to Charleston

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Orbitz now offers free apps for iPad, iPhone, and Android users. You can use Orbitz on these devices to search for affordable fares and to book flights from Quad Cities to Charleston. Mobile apps also allow users to view, compare, and book hotel rooms with just a few taps on the screen and let you access up-to-date flight and baggage claim information in a matter of seconds.

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Keep Everyone Updated With Flight Alerts

Orbitz is the ideal way to book flights from Quad Cities to Charleston. Free Orbitz alerts can be sent to you and as many as six of your contacts about changes to your Quad Cities to Charleston flights. This keeps everyone notified of flight delays or any other disruptions that might impact your arrival time.

Orbitz Makes It Easy to Plan Your Trips on a Budget

You can always find affordable flights from Quad Cities to Charleston on Orbitz. Use different airlines to book arrival and departure flights, take advantage of vacation package deals, and secure exclusive rewards.

Frequently asked questions

What is the shortest flight from Quad Cities to Charleston?
With the journey from Quad Cities to Charleston taking a minimum of 3 hours, you’ll have enough time to sit back and enjoy the experience. Order an in-flight vino and get cozy in your seat with a gripping book or movie.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won’t keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.