$251 Cheap flight deals from Tampa (TPA) to Panama City (PTY)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

This Weekend's Flight Deals from Tampa to Panama City

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, May 10 - Thu, May 21
TPA
Tampa Intl.
PTY
Tocumen Intl.
$485 Roundtrip, found 6 days ago
$485
Roundtrip
found 6 days ago
Select avianca flight, departing Sun, May 10 from Tampa Intl. to Tocumen Intl., returning Thu, May 21, priced at $485 found 6 days ago
Fri, May 8 - Mon, May 11
SRQ
Sarasota-Bradenton Intl.
PTY
Tocumen Intl.
$849 Roundtrip, found 5 days ago
$849
Roundtrip
found 5 days ago
Select Delta flight, departing Fri, May 8 from Sarasota-Bradenton Intl. to Tocumen Intl., returning Mon, May 11, priced at $849 found 5 days ago

Airfares from $251 One Way, $306 Round Trip from Tampa to Panama City

Prices starting at $306 for return flights and $251 for one-way flights to Panama City were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Mon, May 25 - Mon, Jun 8
TPA
Tampa
PTY
Panama City
$306 Roundtrip, found 3 days ago
$306
Roundtrip
found 3 days ago
Select avianca flight, departing Mon, May 25 from Tampa to Panama City, returning Mon, Jun 8, priced at $306 found 3 days ago
Fri, May 15 - Sun, Jun 7
TPA
Tampa
PTY
Panama City
$311 Roundtrip, found 2 days ago
$311
Roundtrip
found 2 days ago
Select avianca flight, departing Fri, May 15 from Tampa to Panama City, returning Sun, Jun 7, priced at $311 found 2 days ago
Mon, May 18 - Fri, May 29
TPA
Tampa
PTY
Panama City
$436 Roundtrip, found 3 days ago
$436
Roundtrip
found 3 days ago
Select avianca flight, departing Mon, May 18 from Tampa to Panama City, returning Fri, May 29, priced at $436 found 3 days ago
Tue, Jun 9 - Fri, Jun 26
TPA
Tampa
PTY
Panama City
$445 Roundtrip, found 3 days ago
$445
Roundtrip
found 3 days ago
Select avianca flight, departing Tue, Jun 9 from Tampa to Panama City, returning Fri, Jun 26, priced at $445 found 3 days ago
Mon, Jul 27 - Wed, Jul 29
TPA
Tampa
PTY
Panama City
$576 Roundtrip, found 2 days ago
$576
Roundtrip
found 2 days ago
Select Copa flight, departing Mon, Jul 27 from Tampa to Panama City, returning Wed, Jul 29, priced at $576 found 2 days ago

Panama City economy flight packages

Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Panama
5.0-star property

Hotel Riu Plaza Panama

9/10 Wonderful! (5,374 reviews)

Jun 10 - Jun 13

3 night stay

Orlando (MCO) to Panama City (PTY)

Copa • Roundtrip • Coach
Price was $1,065, price is now $834 per person
$834
per person
found 1 day ago
Great place to stay and great service

Reviewed on Apr 14, 2026

Central Hotel Panama Casco Viejo
4.0-star property

Central Hotel Panama Casco Viejo

9.2/10 Wonderful! (1,005 reviews)

Jun 10 - Jun 13

3 night stay

Orlando (MCO) to Panama City (PTY)

Copa • Roundtrip • Coach
Price was $1,387, price is now $1,031 per person
$1,031
per person
found 1 day ago
Good breakfast. Perfect location. Big rooms. All good.

Reviewed on Apr 13, 2026

Villa Marina Hotel
3.5-star property

Villa Marina Hotel

9/10 Wonderful! (157 reviews)

Jun 18 - Jun 23

5 night stay

Orlando (MCO) to Panama City (PTY)

Copa • Roundtrip • Coach
Price was $1,229, price is now $922 per person
$922
per person
found 1 day ago
The front desk staff was very friendly and helpful. The condo was clean and a perfect size for our family of 4. The kitchen had all of the pots/cutlery you would want, but it would be nice to have a simple salt/pepper. They have separate towels for the pool areas/beach, which was nice, but no wash cloths. They don’t seem to be a thing in Panama in general. The pool near the condos was really nice, but it would be better if they had more stones/paving/grass around it bc there was quite a bit of dirt and it was hard to keep from tracking it into the pool. The restaurant was good and the waitress was very sweet. All in all a great spot away from the noise of the other resorts that have music late, etc.

Reviewed on Apr 12, 2024

Don't see what you're looking for?
See all available trips from Tampa to Panama City
View all trips

More About Flying To Panama City from Tampa

Route Information for Flights from Tampa to Panama City

Origin Airport IATA Code
TPA
Destination Airport IATA Code
PTY
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Tampa to Panama City

When you’re ready to take your next trip, get the most affordable prices on flights from Tampa to Panama City with Orbitz! The guaranteed low prices and cutting-edge mobile tools on Orbits make it easy for you to plan your next great vacation.

Keep Up With Sudden Flight Changes

As any traveler knows, air travel can suddenly be temporarily halted due to service disruptions. Along with offering the best fares for flights from Tampa to Panama City, Orbitz also offers free mobile phone and email alerts that help you keep up with sudden changes to your flight plans. Choose from email, text, or voice message alerts.

Get Great Prices for Tampa to Panama City Flights

Orbitz features both an Android app and an iPhone app to give you the lowest prices for Tampa to Panama City flights. Use these mobile apps to get updates on your flight, the details of your itinerary, and to learn about available hotel deals in the area.

Fly for Less and Earn Miles

Did you know you can earn miles and points for your frequent flyer program with Orbitz? To do this with specific flights from Tampa to Panama City, enter your frequent flyer account number when you book your ticket online. For even more convenience, keep a record of your loyalty travel program numbers directly with Orbitz by storing them in your account profile. This way, you can add your account numbers to your next reservation for Tampa to Panama City flights automatically without the annoying hassle of having to look them up.

Frequently asked questions

Are there non-stop flights from Tampa to Panama City?
Get your passport ready, because Copa Airlines will fly you directly from Tampa to Panama City. Book your plane ticket now and enjoy a stress-free, nonstop flight.
What is the shortest flight from Tampa to Panama City?
Getting from Tampa Airport to Panama Airport will take a minimum of 3 hours and 50 minutes. Enjoy a wine and watch a flick or two — it's a golden opportunity to chill out.
What airlines fly from Tampa to Panama City most frequently?
If you want the airline with the most flights from Tampa, FL (TPA-Tampa Intl.) to Tocumen Intl. Airport (PTY), buckle up and take off with Copa Airlines. This airline offers 17 flights per month along this route.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.