
$178 Cheap flight deals from Myrtle Beach (MYR) to Charleston (STL)
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This Weekend's Flight Deals from Myrtle Beach to Charleston
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $178 One Way, $351 Round Trip from Myrtle Beach to Charleston
Prices starting at $351 for return flights and $178 for one-way flights to Charleston were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Charleston economy flight packages

The Knight Center at Washington University
Feb 4 - Feb 8
Myrtle Beach (MYR) to St. Louis (STL)
St. Louis (STL) to Myrtle Beach (MYR)
Reviewed on Sep 15, 2025

Ameristar Casino Resort and Spa
Feb 4 - Feb 8
Myrtle Beach (MYR) to St. Louis (STL)
St. Louis (STL) to Myrtle Beach (MYR)
Reviewed on Dec 2, 2025

Embassy Suites by Hilton St. Louis St. Charles
Feb 4 - Feb 8
Myrtle Beach (MYR) to St. Louis (STL)
St. Louis (STL) to Myrtle Beach (MYR)
Reviewed on Apr 29, 2025
More About Flying To Charleston from Myrtle Beach
Route Information for Flights from Myrtle Beach to Charleston
Origin Airport IATA Code | MYR |
|---|---|
Destination Airport IATA Code | STL |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Myrtle Beach to Charleston
Orbitz gives you great deals on your flights from Myrtle Beach to Charleston. If you also need a discount car rental or a cheap hotel room after you arrived at your destination, Orbitz has you covered.
We Offer Great Travel Deals and Discounts
When you book flights from Myrtle Beach to Charleston with Orbitz for, you can be assured that you are getting the lowest price possible. Orbitz works constantly with our airline partners to ensure guaranteed low prices on Myrtle Beach to Charleston flights for your trip—whether you are traveling for business or for fun with your family.
Enjoy Savings on Last-Minute Flights
If you are looking for a discount price on last-minute flights from Myrtle Beach to Charleston, chances are that Orbitz can offer you a deal that will save you lots of money. Whether you just want to get away for the weekend or go on a vacation lasting weeks, Orbitz can help you find the best deals on Myrtle Beach to Charleston flights that fit your budget and your itinerary for the perfect trip.
Full-Service Mobile Apps
Need more mobility when it comes to travel planning? Orbitz has easy-to-use mobile apps for iPhone, iPad, and Android, to help the traveler on the go. Not only can use the apps to find huge savings on Myrtle Beach to Charleston flights wherever you are, but you can also check out and book discount hotel rooms too. The apps will also keep you up-to-date when it’s time to fly. Get easy access to your itinerary for flights from Myrtle Beach to Charleston and review gate and baggage claim details too.
Flights from Myrtle Beach
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Myrtle Beach Airports
Charleston Airports
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.


