$14 Cheap flight deals from La Serena (LSC) to Santiago (SCL)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Airfares from $14 One Way, $54 Round Trip from La Serena to Santiago

Prices starting at $54 for return flights and $14 for one-way flights to Santiago were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Oct 28 - Wed, Nov 18
LSC
La Serena
SCL
Santiago
$54 Roundtrip, found 1 day ago
$54
Roundtrip
found 1 day ago
Select SKY AIRLINE flight, departing Wed, Oct 28 from La Serena to Santiago, returning Wed, Nov 18, priced at $54 found 1 day ago
Wed, Oct 28 - Wed, Nov 18
LSC
La Serena
SCL
Santiago
$61 Roundtrip, found 1 day ago
$61
Roundtrip
found 1 day ago
Select SKY AIRLINE flight, departing Wed, Oct 28 from La Serena to Santiago, returning Wed, Nov 18, priced at $61 found 1 day ago
Wed, Oct 28 - Wed, Nov 18
LSC
La Serena
SCL
Santiago
$63 Roundtrip, found 1 day ago
$63
Roundtrip
found 1 day ago
Select SKY AIRLINE flight, departing Wed, Oct 28 from La Serena to Santiago, returning Wed, Nov 18, priced at $63 found 1 day ago
Thu, Jan 7 - Wed, Jan 27
LSC
La Serena
SCL
Santiago
$66 Roundtrip, found 3 days ago
$66
Roundtrip
found 3 days ago
Select SKY AIRLINE flight, departing Thu, Jan 7 from La Serena to Santiago, returning Wed, Jan 27, priced at $66 found 3 days ago
Fri, Sep 25 - Sun, Sep 27
LSC
La Serena
SCL
Santiago
$67 Roundtrip, found 4 days ago
$67
Roundtrip
found 4 days ago
Select SKY AIRLINE flight, departing Fri, Sep 25 from La Serena to Santiago, returning Sun, Sep 27, priced at $67 found 4 days ago

More About Flying To Santiago from La Serena

Route Information for Flights from La Serena to Santiago

Origin Airport IATA Code
LSC
Destination Airport IATA Code
SCL
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

La Serena to Santiago

Orbitz has your best deals on La Serena to Santiago flights. From guaranteed low prices to cutting-edge mobile tools, the perfect trip begins on Orbitz.
Get Orbitz On the Go for Flights from La Serena to Santiago
Use our mobile apps for Android and iPhone to find the best price on flights from La Serena to Santiago. Check your flight status, gate and baggage claim details, and book exclusive mobile deals on hotels — even on the same day.

Rack Up Miles While Flying for Cheaper

Earn miles or points toward your frequent flyer program on select La Serena to Santiago flights. When you book your flight on Orbitz, simply add your qualifying frequent flyer number where prompted. You can also store your airline frequent flyer or loyalty program numbers in your Orbitz account profile to automatically add them to your future reservations.

Worry Less With Flight Alerts

Orbitz is the best source for booking flights from La Serena to Santiago. But we also keep you updated about flight delays, booking changes, or service disruptions with free alerts. Get alerts on La Serena to Santiago flights sent to your email or via voice or text to your mobile phone. We can also send the alerts to up to 6 other email addresses or phone numbers, which is helpful if you are being picked up at the airport.

Budget Travel Planning Made Easy

It's easy to find discount air tickets for flights from La Serena to Santiago on Orbitz. Mix and match airlines for your departing and your returning flights to find the lowest fares and the best schedule.

Frequently asked questions

Are there non-stop flights from La Serena to Santiago?
Fasten your seat belt and enjoy a relaxing flight with one of the 3 airlines that fly straight from La Florida Airport (LSC) to Santiago (SCL-Arturo Merino Benitez). We've complied a list of popular carriers to book with:

  • LATAM Airlines
  • Sky Airline
  • JetSmart

What is the shortest flight from La Serena to Santiago?
The journey from La Serena to Santiago can be as fast as 47 minutes. With a leisurely flight time like this, why not book a spontaneous getaway?
What airlines fly from La Serena to Santiago most frequently?
Check out LATAM Airlines (LA). This airline offers some of the most frequent flights from La Serena La Florida Airport to SCL. It operates 134 services on this route each month and is popular with passengers. Sky Airline (H2) will also get you to your destination in comfort and style. Offering 65 flights every month between La Serena and Santiago, it's another quality airline to look into.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.