$244 Cheap flight deals from St. Louis (STL) to Siena (FLR)

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This Weekend's Flight Deals from St. Louis to Siena

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Feb 20 - Sun, Mar 1
STL
Lambert-St. Louis Intl.
FLR
Peretola
$705 Roundtrip, found 5 hours ago
$705
Roundtrip
found 5 hours ago
Select Lufthansa flight, departing Fri, Feb 20 from Lambert-St. Louis Intl. to Peretola, returning Sun, Mar 1, priced at $705 found 5 hours ago

Airfares from $244 One Way, $557 Round Trip from St. Louis to Siena

Prices starting at $557 for return flights and $244 for one-way flights to Siena were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Apr 15 - Tue, Apr 21
STL
St. Louis
FLR
Florence
$557 Roundtrip, found 3 days ago
$557
Roundtrip
found 3 days ago
Select British Airways flight, departing Wed, Apr 15 from St. Louis to Florence, returning Tue, Apr 21, priced at $557 found 3 days ago
Wed, Nov 18 - Wed, Nov 25
STL
St. Louis
FLR
Florence
$563 Roundtrip, found 4 days ago
$563
Roundtrip
found 4 days ago
Select Lufthansa flight, departing Wed, Nov 18 from St. Louis to Florence, returning Wed, Nov 25, priced at $563 found 4 days ago
Wed, Apr 15 - Tue, Apr 21
STL
St. Louis
FLR
Florence
$616 Roundtrip, found 3 days ago
$616
Roundtrip
found 3 days ago
Select Iberia flight, departing Wed, Apr 15 from St. Louis to Florence, returning Tue, Apr 21, priced at $616 found 3 days ago
Sat, Nov 7 - Sat, Nov 14
STL
St. Louis
FLR
Florence
$618 Roundtrip, found 6 days ago
$618
Roundtrip
found 6 days ago
Select Delta flight, departing Sat, Nov 7 from St. Louis to Florence, returning Sat, Nov 14, priced at $618 found 6 days ago
Sat, Nov 7 - Sat, Nov 14
STL
St. Louis
FLR
Florence
$629 Roundtrip, found 6 days ago
$629
Roundtrip
found 6 days ago
Select Air Canada flight, departing Sat, Nov 7 from St. Louis to Florence, returning Sat, Nov 14, priced at $629 found 6 days ago

Siena economy flight packages

Price found within the past 48 hours. Click for updated prices.
Albergo Ristorante Poli
2.0-star property

Albergo Ristorante Poli

9.2/10 Wonderful! (136 reviews)

Mar 21 - Mar 25

4 night stay

St. Louis (STL) to Florence (FLR)

Delta • Coach

Florence (FLR) to St. Louis (STL)

KLM • Coach
Price was $782, price is now $768 per person
$768
per person
just found
This was probably the most happy we have ever stayed at a property. The restaurant there was fantastic, pasta and pizza options. All fresh and prepared with love every day. The employees were awesome and did everything in their power to make our stay great. We absolutely did not want to leave. We will be back at some point. The location is in a great little village that is gorgeous and quiet. If you don't mind some driving in is pretty much centralized to most of attractions in central and northern Italy.

Reviewed on Jul 12, 2025

Palazzo Loup
4.0-star property

Palazzo Loup

8.6/10 Excellent! (105 reviews)

Mar 21 - Mar 25

4 night stay

St. Louis (STL) to Florence (FLR)

Delta • Coach

Florence (FLR) to St. Louis (STL)

KLM • Coach
Price was $885, price is now $857 per person
$857
per person
just found
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More About Flying To Siena from St. Louis

Route Information for Flights from St. Louis to Siena

Origin Airport IATA Code
STL
Destination Airport IATA Code
FLR
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

St. Louis to Siena

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.