$316 Cheap flight deals from Santiago (SCL) to Panama City (PTY)

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Airfares from $316 One Way, $658 Round Trip from Santiago to Panama City

Prices starting at $658 for return flights and $316 for one-way flights to Panama City were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Aug 26 - Mon, Aug 31
SCL
Santiago
PTY
Panama City
$658 Roundtrip, just found
$658
Roundtrip
just found
Select avianca flight, departing Wed, Aug 26 from Santiago to Panama City, returning Mon, Aug 31, priced at $658 just found
Sat, Aug 22 - Mon, Aug 31
SCL
Santiago
PTY
Panama City
$662 Roundtrip, just found
$662
Roundtrip
just found
Select avianca flight, departing Sat, Aug 22 from Santiago to Panama City, returning Mon, Aug 31, priced at $662 just found
Wed, Jun 10 - Wed, Jun 24
SCL
Santiago
PTY
Panama City
$669 Roundtrip, found 2 days ago
$669
Roundtrip
found 2 days ago
Select avianca flight, departing Wed, Jun 10 from Santiago to Panama City, returning Wed, Jun 24, priced at $669 found 2 days ago
Thu, Jun 18 - Sun, Jun 21
SCL
Santiago
PTY
Panama City
$695 Roundtrip, found 22 hours ago
$695
Roundtrip
found 22 hours ago
Select avianca flight, departing Thu, Jun 18 from Santiago to Panama City, returning Sun, Jun 21, priced at $695 found 22 hours ago
Wed, Jun 17 - Thu, Jun 25
SCL
Santiago
PTY
Panama City
$699 Roundtrip, found 19 hours ago
$699
Roundtrip
found 19 hours ago
Select avianca flight, departing Wed, Jun 17 from Santiago to Panama City, returning Thu, Jun 25, priced at $699 found 19 hours ago

Panama City business class flight packages

Price found within the past 48 hours. Click for updated prices.
Megapolis Hotel Panamá
4.5-star property

Megapolis Hotel Panamá

8.4/10 Very Good! (1,528 reviews)

Jul 1 - Jul 8

7 night stay

Santiago (SCL) to Panama City (PTY)

Avianca • Non-stop roundtrip • BusinessClass
Price was $2,444, price is now $1,836 per person
$1,836
per person
found 5 hours ago
Room was very clean, breakfast was great.Easy check in.

Reviewed on Nov 16, 2025

Boutique Apartments Panamá Coco del Mar
3.5-star property

Boutique Apartments Panamá Coco del Mar

7.6/10 Good! (197 reviews)

Jul 1 - Jul 8

7 night stay

Santiago (SCL) to Panama City (PTY)

Avianca • Non-stop roundtrip • BusinessClass
Save 100% on your flight
Price was $5,004, price is now $3,450 per person
$3,450
per person
found 5 hours ago
This apartment was in a good location with a nice view. It was in the 27th floor. But my husband has a fear of height so it wasn’t helpful for him. There was one bedroom without a curtain so it was too bright to sleep. When we checked in they gave us only one key card and we are a family with 6 people, making it inconvenient. So I contacted them to get the 2nd key card and they responded right away. My unit has a washing machine and a dryer.

Reviewed on Apr 13, 2026

Las Americas Golden Tower Panama
4.0-star property

Las Americas Golden Tower Panama

9/10 Wonderful! (1,019 reviews)

Jul 1 - Jul 8

7 night stay

Santiago (SCL) to Panama City (PTY)

Avianca • Non-stop roundtrip • BusinessClass
Price was $2,573, price is now $1,923 per person
$1,923
per person
found 5 hours ago
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More About Flying To Panama City from Santiago

Route Information for Flights from Santiago to Panama City

Origin Airport IATA Code
SCL
Destination Airport IATA Code
PTY
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Santiago to Panama City

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Frequently asked questions

Are there non-stop flights from Santiago to Panama City?
Copa Airlines flies nonstop from Santiago to Panama City, so all you need to do is kick back and relax until you reach Tocumen Intl. Airport (PTY).
What is the shortest flight from Santiago to Panama City?
The shortest flight time from Santiago to Panama City is 7 hours and 40 minutes. Order your favorite wine from the drink cart, work on your travel itinerary or get to know your seat mate — you'll have plenty of time on this medium-haul trip.
What airlines fly from Santiago to Panama City most frequently?
Copa Airlines is the most frequent airline operating on the Santiago to Panama City route. Choose from 91 flights each month with this carrier.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.