$81 Cheap flight deals from Orlando (ORL) to Cherokee (TYS)

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This Weekend's Flight Deals from Orlando to Cherokee

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Jan 10 - Sat, Jan 17
MCO
Orlando Intl.
TYS
McGhee Tyson
$239 Roundtrip, found 4 days ago
$239
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Jan 10 from Orlando Intl. to McGhee Tyson, returning Sat, Jan 17, priced at $239 found 4 days ago
Fri, Jan 9 - Sat, Jan 17
MCO
Orlando Intl.
AVL
Asheville Regional
$448 Roundtrip, found 11 hours ago
$448
Roundtrip
found 11 hours ago
Select Delta flight, departing Fri, Jan 9 from Orlando Intl. to Asheville Regional, returning Sat, Jan 17, priced at $448 found 11 hours ago

Airfares from $81 One Way, $173 Round Trip from Orlando to Cherokee

Prices starting at $173 for return flights and $81 for one-way flights to Cherokee were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Jan 22 - Mon, Jan 26
MCO
Orlando
TYS
Knoxville
$173 Roundtrip, found 1 day ago
$173
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Jan 22 from Orlando to Knoxville, returning Mon, Jan 26, priced at $173 found 1 day ago
Wed, Jan 28 - Sat, Jan 31
MCO
Orlando
TYS
Knoxville
$188 Roundtrip, found 4 days ago
$188
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Jan 28 from Orlando to Knoxville, returning Sat, Jan 31, priced at $188 found 4 days ago
Thu, Jan 22 - Mon, Feb 2
MCO
Orlando
TYS
Knoxville
$194 Roundtrip, found 1 day ago
$194
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Jan 22 from Orlando to Knoxville, returning Mon, Feb 2, priced at $194 found 1 day ago
Wed, Jan 28 - Sat, Jan 31
MCO
Orlando
TYS
Knoxville
$196 Roundtrip, found 4 days ago
$196
Roundtrip
found 4 days ago
Select Delta flight, departing Wed, Jan 28 from Orlando to Knoxville, returning Sat, Jan 31, priced at $196 found 4 days ago
Mon, Jan 26 - Mon, Feb 2
MCO
Orlando
TYS
Knoxville
$198 Roundtrip, found 1 day ago
$198
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, Jan 26 from Orlando to Knoxville, returning Mon, Feb 2, priced at $198 found 1 day ago

Cherokee economy flight packages

Price found within the past 48 hours. Click for updated prices.
Holiday Inn Asheville East-Blue Ridge PKWY by IHG
3.0-star property

Holiday Inn Asheville East-Blue Ridge PKWY by IHG

9.2/10 Wonderful! (1,000 reviews)

Feb 11 - Feb 15

4 night stay

Orlando (MCO) to Asheville (AVL)

Delta • Non-stop roundtrip • Coach
Price was $555, price is now $401 per person
$401
per person
found 1 day ago
We enjoyed our stay at this property. We had a mountain view room and the room did not disappoint with a microwave and tall mini refrigerator. The room was also spacious for two people. The bed/ pillows were comfortable and most importantly, the shower water pressure was great! The side entrance doors (near the parking lot) are locked after 6p, which I found very safe, so not anyone can just come in. The gym, we didn't use, but it had an elliptical, treadmill and a selection of free weights. The outdoor swimming pool is currently being renovated. They didn't have coffee on arrival in the lobby but they had tea/ hot chocolate. The complimentary coffee was fresh in the morning in the lobby. The only irritating thing about the hotel was that the housekeeping knocking frequently before our 11am checkout to see if we had left our room. Both times, I had told her we are not ready and she was sorry for the interruption. The first time, she unlocked herself and was about to walk in when I walked up in time to tell her we were not ready to leave yet. Having said that, we will come and stay again. This hotel had everything we needed for our stay.

Reviewed on Apr 28, 2025

Holiday Inn Club Vacations Smoky Mountain Resort by IHG
3.0-star property

Holiday Inn Club Vacations Smoky Mountain Resort by IHG

9/10 Wonderful! (472 reviews)

Feb 18 - Feb 22

4 night stay

Orlando (MCO) to Knoxville (TYS)

American Airlines • Non-stop roundtrip • Coach
Save 100% on your flight
Price was $986, price is now $719 per person
$719
per person
found 19 hours ago
Great stay! Very clean and great staff! Would definitely stay here again!

Reviewed on Jul 21, 2016

Four Points by Sheraton Asheville Downtown
3.0-star property

Four Points by Sheraton Asheville Downtown

8.4/10 Very Good! (1,004 reviews)

Feb 11 - Feb 15

4 night stay

Orlando (MCO) to Asheville (AVL)

Delta • Non-stop roundtrip • Coach
Price was $747, price is now $547 per person
$547
per person
found 1 day ago
This is certainly a no-frills hotel. It’s in a great location that’s walkable to everything in downtown Asheville but it’s badly in need of a renovation. The free parking is a nice amenity but the towels in the bathroom are very old and feel like sandpaper. The rates here are less expensive than other and much nicer hotels in downtown so I guess you get what you pay for.

Reviewed on Dec 28, 2025

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More About Flying To Cherokee from Orlando

Route Information for Flights from Orlando to Cherokee

Origin Airport IATA Code
ORL
Destination Airport IATA Code
TYS
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Orlando to Cherokee

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.