$77 Cheap flight deals from Minneapolis - St. Paul (MSP) to Isle of Palms (CHS)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

This Weekend's Flight Deals from Minneapolis - St. Paul to Isle of Palms

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Feb 1 - Sat, Feb 7
MSP
Minneapolis - St. Paul Intl.
CHS
Charleston Intl.
$542 Roundtrip, found 1 day ago
$542
Roundtrip
found 1 day ago
Select Delta flight, departing Sun, Feb 1 from Minneapolis - St. Paul Intl. to Charleston Intl., returning Sat, Feb 7, priced at $542 found 1 day ago

Airfares from $77 One Way, $164 Round Trip from Minneapolis - St. Paul to Isle of Palms

Prices starting at $164 for return flights and $77 for one-way flights to Isle of Palms were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Apr 25 - Thu, May 7
MSP
Minneapolis
CHS
Charleston
$164 Roundtrip, found 1 day ago
$164
Roundtrip
found 1 day ago
Select Sun Country Airlines flight, departing Sat, Apr 25 from Minneapolis to Charleston, returning Thu, May 7, priced at $164 found 1 day ago
Sat, Apr 25 - Thu, Apr 30
MSP
Minneapolis
CHS
Charleston
$167 Roundtrip, found 14 hours ago
$167
Roundtrip
found 14 hours ago
Select Sun Country Airlines flight, departing Sat, Apr 25 from Minneapolis to Charleston, returning Thu, Apr 30, priced at $167 found 14 hours ago
Sun, Apr 19 - Thu, May 7
MSP
Minneapolis
CHS
Charleston
$174 Roundtrip, found 1 day ago
$174
Roundtrip
found 1 day ago
Select Sun Country Airlines flight, departing Sun, Apr 19 from Minneapolis to Charleston, returning Thu, May 7, priced at $174 found 1 day ago
Sun, May 31 - Mon, Jun 1
MSP
Minneapolis
CHS
Charleston
$179 Roundtrip, found 4 days ago
$179
Roundtrip
found 4 days ago
Select Sun Country Airlines flight, departing Sun, May 31 from Minneapolis to Charleston, returning Mon, Jun 1, priced at $179 found 4 days ago
Thu, May 28 - Thu, Jun 4
MSP
Minneapolis
CHS
Charleston
$184 Roundtrip, found 4 days ago
$184
Roundtrip
found 4 days ago
Select Sun Country Airlines flight, departing Thu, May 28 from Minneapolis to Charleston, returning Thu, Jun 4, priced at $184 found 4 days ago

Isle of Palms economy flight packages

Price found within the past 48 hours. Click for updated prices.
The Ryder Hotel
3.5-star property

The Ryder Hotel

8.6/10 Excellent! (1,002 reviews)

Feb 26 - Mar 1

3 night stay

Minneapolis (MSP) to Charleston (CHS)

American Airlines • Non-stop roundtrip • Coach
Save 100% on your flight
Price was $1,175, price is now $818 per person
$818
per person
found 1 day ago
Love this hotel for the clean room, really great staff and the bar and pool area.

Reviewed on May 11, 2025

King 583
2.0-star property

King 583

9/10 Wonderful! (177 reviews)

Feb 28 - Mar 5

5 night stay

Minneapolis (MSP) to Charleston (CHS)

Delta • Roundtrip • Coach
Save 100% on your flight
Price was $1,426, price is now $903 per person
$903
per person
found 4 hours ago
Great location. Room had everything we need. Staff was kind and helpful.

Reviewed on Jan 4, 2026

The Francis Marion Hotel
4.0-star property

The Francis Marion Hotel

9/10 Wonderful! (1,942 reviews)

Mar 7 - Mar 10

3 night stay

Minneapolis (MSP) to Charleston (CHS)

American Airlines • Non-stop roundtrip • Coach
Price was $1,087, price is now $829 per person
$829
per person
found 1 day ago
My sister and I stayed here for our trip to Charleston and this hotel did not disappoint. You get exactly what you’re looking for, a historic hotel within walking distance, a beautiful lobby and interior with updated rooms but still having that old charm to it. The room was spacious with 2 large closets and a full length mirror (very much appreciated by my sister and I) The bathroom was smaller but to be expected with older hotels, the only downfall was the plumbing. The water pressure wasn’t the greatest so made for longer showers and the toilets didn’t flush well. But the hotel is in a perfect area. We flew in and didn't have personal transportation and were able to walk all over for great shopping, restaurants and sites. If we decide to return for another trip to Charleston we would definitely stay here again. We didn’t get a chance to try the restaurant in the hotel but it’s very convenient to have as well as a coffee shop.

Reviewed on Oct 28, 2025

Don't see what you're looking for?
See all available trips from Minneapolis - St. Paul to Isle of Palms
View all trips

Isle of Palms first class flight packages

Price found within the past 48 hours. Click for updated prices.
King 583
2.0-star property

King 583

9/10 Wonderful! (177 reviews)

Feb 26 - Mar 2

4 night stay

Minneapolis (MSP) to Charleston (CHS)

Delta • Roundtrip • FirstClass
Price was $2,328, price is now $1,877 per person
$1,877
per person
found 1 day ago
Great location. Room had everything we need. Staff was kind and helpful.

Reviewed on Jan 4, 2026

The Ryder Hotel
3.5-star property

The Ryder Hotel

8.6/10 Excellent! (1,002 reviews)

Feb 26 - Mar 2

4 night stay

Minneapolis (MSP) to Charleston (CHS)

Delta • Roundtrip • FirstClass
Price was $2,471, price is now $2,031 per person
$2,031
per person
found 1 day ago
Love this hotel for the clean room, really great staff and the bar and pool area.

Reviewed on May 11, 2025

Emeline
4.0-star property

Emeline

9.4/10 Exceptional! (1,661 reviews)

Feb 26 - Mar 2

4 night stay

Minneapolis (MSP) to Charleston (CHS)

Delta • Roundtrip • FirstClass
Price was $2,716, price is now $2,271 per person
$2,271
per person
found 1 day ago
Front desk was not that welcoming. Valet parking was very slow and sometimes not found

Reviewed on Sep 18, 2025

Don't see what you're looking for?
See all available trips from Minneapolis - St. Paul to Isle of Palms
View all trips

More About Flying To Isle of Palms from Minneapolis - St. Paul

Route Information for Flights from Minneapolis - St. Paul to Isle of Palms

Origin Airport IATA Code
MSP
Destination Airport IATA Code
CHS
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Minneapolis - St. Paul to Isle of Palms

Grab great fares on Minneapolis - St. Paul to Isle of Palms flights with Orbitz, your #1 source for discount international and domestic air tickets. Our cutting-edge mobile tools and great online search functionality make booking your next budget trip a breeze.

Mobile Apps for Exclusive Deals on Flights From Minneapolis - St. Paul to Isle of Palms

You don’t have to sit down at a computer to find the latest flight bargains. Orbitz offers a mobile app for Android, iPhone, and tablet devices, which will keep you alert to fantastic fares, hotel discounts, and more great savings. The app gives you real-time low fares for flights from Minneapolis - St. Paul to Isle of Palms and lets you book your hotel room with a few simple clicks.

Find Your Minneapolis - St. Paul to Isle of Palms Flights, Car, and Hotel in One Place

Orbitz gives you the latest deals on air fares, hotels, cruises, and car rentals at up to 50% off. Booking your flights from Minneapolis - St. Paul to Isle of Palms is easy whether you are using a computer, with the Orbitz mobile app, or through m.orbitz.com on your mobile device’s Web browser.

Stay Informed on Your Trip

Orbitz sends you alerts about the latest updates to your Minneapolis - St. Paul to Isle of Palms flights, such as delays. Receive the updates via your email or mobile phone. Use the Orbitz app to stay updated on your flight status and baggage claim details.

Earn Miles for Flights From Minneapolis - St. Paul to Isle of Palms

On qualified flights, add your frequent flyer number to your booking to get miles or points for your trip.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.