$101 Cheap flight deals from Houston (HOU) to Southwest Illinois (STL)

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This Weekend's Flight Deals from Houston to Southwest Illinois

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, May 24 - Fri, May 29
IAH
George Bush Intercontinental
STL
Lambert-St. Louis Intl.
$705 Roundtrip, found 2 days ago
$705
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Sun, May 24 from George Bush Intercontinental to Lambert-St. Louis Intl., returning Fri, May 29, priced at $705 found 2 days ago
Sun, May 24 - Fri, May 29
IAH
George Bush Intercontinental
STL
Lambert-St. Louis Intl.
$705 Roundtrip, found 2 days ago
$705
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Sun, May 24 from George Bush Intercontinental to Lambert-St. Louis Intl., returning Fri, May 29, priced at $705 found 2 days ago

Airfares from $101 One Way, $195 Round Trip from Houston to Southwest Illinois

Prices starting at $195 for return flights and $101 for one-way flights to Southwest Illinois were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Jul 7 - Wed, Jul 8
IAH
Houston
STL
St. Louis
$195 Roundtrip, found 5 days ago
$195
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Tue, Jul 7 from Houston to St. Louis, returning Wed, Jul 8, priced at $195 found 5 days ago
Thu, Aug 13 - Wed, Aug 19
IAH
Houston
STL
St. Louis
$204 Roundtrip, found 5 days ago
$204
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Thu, Aug 13 from Houston to St. Louis, returning Wed, Aug 19, priced at $204 found 5 days ago
Sat, Jun 13 - Wed, Jun 24
IAH
Houston
STL
St. Louis
$209 Roundtrip, found 6 days ago
$209
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Sat, Jun 13 from Houston to St. Louis, returning Wed, Jun 24, priced at $209 found 6 days ago
Thu, Aug 13 - Wed, Aug 19
IAH
Houston
STL
St. Louis
$210 Roundtrip, found 5 days ago
$210
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Thu, Aug 13 from Houston to St. Louis, returning Wed, Aug 19, priced at $210 found 5 days ago
Tue, Jul 7 - Wed, Jul 8
IAH
Houston
STL
St. Louis
$215 Roundtrip, found 5 days ago
$215
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Tue, Jul 7 from Houston to St. Louis, returning Wed, Jul 8, priced at $215 found 5 days ago

Southwest Illinois economy flight packages

Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel
3.5-star property

The Wildwood Hotel

9.2/10 Wonderful! (1,634 reviews)

Jun 22 - Jun 26

4 night stay

Houston (HOU) to St. Louis (STL)

Southwest Airlines • Coach

St. Louis (STL) to Houston (HOU)

Frontier Airlines • Coach
Price was $910, price is now $614 per person
$614
per person
found 1 day ago
Hotel was clean but honestly, outdated. Staff was great. The continental breakfast was fine. Biggest issue was the shower. There was next to no water pressure no matter the time of day. The mattress also felt cheap. I’m not a picky person and overall, I would stay again. Just maybe not in an upgraded room. I don’t feel like it was worth it.

Reviewed on Feb 24, 2026

Residence Inn by Marriott St Louis Downtown
3.0-star property

Residence Inn by Marriott St Louis Downtown

7.8/10 Good! (1,005 reviews)

Jun 22 - Jun 26

4 night stay

Houston (HOU) to St. Louis (STL)

Southwest Airlines • Coach

St. Louis (STL) to Houston (HOU)

Frontier Airlines • Coach
Price was $867, price is now $678 per person
$678
per person
found 1 day ago
Unfortunately, this hotel is not in the best location and is not walkable at all. However it is convenient to SLU and surrounding areas. The property itself is a little run down and I've elevator was down while we were there. Me thankfully, we were on the third floor and could take the stairs. Paying for parking is ridiculous given that we paid for the room and it should be included. I wouldn't start here again knowing that, but it's a decent place to stay right off the highway

Reviewed on Sep 28, 2025

The Knight Center at Washington University
2.5-star property

The Knight Center at Washington University

9.4/10 Exceptional! (541 reviews)

Jun 22 - Jun 26

4 night stay

Houston (HOU) to St. Louis (STL)

Southwest Airlines • Coach

St. Louis (STL) to Houston (HOU)

Frontier Airlines • Coach
Price was $890, price is now $717 per person
$717
per person
found 1 day ago
Very nice lobby restaurant and bar

Reviewed on Sep 15, 2025

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More About Flying To Southwest Illinois from Houston

Route Information for Flights from Houston to Southwest Illinois

Origin Airport IATA Code
HOU
Destination Airport IATA Code
STL
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Houston to Southwest Illinois

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.