$188 Cheap flight deals from Detroit (DTT) to Simpsonville (GSP)
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
Airfares from $188 One Way, $319 Round Trip from Detroit to Simpsonville
Prices starting at $319 for return flights and $188 for one-way flights to Simpsonville were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Simpsonville economy flight packages
Park Place Apartments by Landing
Feb 6 - Feb 13
Detroit (DTW) to Greenville (GSP)
Reviewed on Sep 6, 2025
Hotel Hartness
Feb 6 - Feb 13
Detroit (DTW) to Greenville (GSP)
Reviewed on Mar 18, 2025
Homewood Suites by Hilton Greenville Downtown
Feb 6 - Feb 13
Detroit (DTW) to Greenville (GSP)
Reviewed on Jul 23, 2025
More About Flying To Simpsonville from Detroit
Route Information for Flights from Detroit to Simpsonville
Origin Airport IATA Code | DTT |
|---|---|
Destination Airport IATA Code | GSP |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Detroit to Simpsonville
If you are looking to find the best deals on Detroit to Simpsonville flights, look no further than Orbitz. Orbitz offers guaranteed low prices as well as cutting-edge mobile tools to help you book cheap flights from Detroit to Simpsonville.
Mobile Apps Make Life Easier
Our mobile apps for Android and iPhone phones as well as tablets and iPads let you find the cheapest flights from Detroit to Simpsonville—whether you are at home or running errands. Use the apps to also keep track of delays to your Detroit to Simpsonville flights and baggage claim information.
Get Miles for Your Flights From Detroit to Simpsonville
It’s easy to earn points or miles for your frequent flyer or airline loyalty program on qualifying Detroit to Simpsonville flights with Orbitz. You can add your frequent flyer number to your online flight booking, and even store your numbers in your Orbitz account profile so they automatically get added the next time you book a flight.
Stay Informed While You Travel
Orbitz keeps you updated on information that’s relevant to your flights from Detroit to Simpsonville. We can send you and six of your personal contacts free travel alerts via SMS text, voicemail, or email, so you instantly know about flight delays or changes.
Keep More Money in Your Pocket With Discount Flights
Orbitz looks for the best deals on Detroit to Simpsonville flights for you. Mix and match airlines for your departing and return flights to fit your travel schedule and budget.
Flights from Detroit
- Detroit to Orlando
- Detroit to Dallas
- Detroit to New York
- Detroit to Chicago
- Detroit to San Francisco
- Detroit to Houston
- Detroit to New Orleans
- Detroit to Los Angeles
- Detroit to San Diego
- Detroit to London
- Detroit to Washington
- Detroit to Toronto
- Detroit to Paris
- Detroit to Atlantic City
- Detroit to Charlotte
- Detroit to Montreal
- Detroit to Sacramento
- Detroit to Hartford
- Detroit to Beijing
- Detroit to Kansas City
Simpsonville Airports
More Destinations
- Flights from Athens to Fountain Inn
- Flights from Atlanta to Fountain Inn
- Flights from Cleveland to Fountain Inn
- Flights from Dallas to Fountain Inn
- Flights from Denver to Fountain Inn
- Flights from Toronto to Fountain Inn
- Flights from Washington to Fountain Inn
- Flights from Charleston to Fountain Inn
- Flights from Jacksonville to Fountain Inn
- Flights from Myrtle Beach to Fountain Inn
- Flights from Manchester to Fountain Inn
- Flights from Sarasota to Fountain Inn
- Flights from Chattanooga to Fountain Inn
- Flights from Cali to Fountain Inn
- Flights from Corpus Christi to Fountain Inn
- Flights from Boston to Mauldin
- Flights from Minneapolis - St. Paul to Mauldin
- Flights from Montreal to Mauldin
- Flights from Phoenix to Mauldin
- Flights from Budapest to Mauldin
- Flights from Charleston to Mauldin
- Flights from Accra to Mauldin
- Flights from Augusta to Mauldin
- Flights from Fort Lauderdale to Mauldin
- Flights from Tulsa to Mauldin
- Flights from South Bend to Mauldin
- Flights from Daytona Beach to Mauldin
- Flights from Louisville to Mauldin
- Flights from Edinburgh to Mauldin
- Flights from Columbia to Mauldin
- Flights from Allentown (ABE) to Greenville (GSP)
- Flights from Albany (ALB) to Greenville (GSP)
- Flights from Altoona (AOO) to Greenville (GSP)
- Flights from Watertown (ART) to Greenville (GSP)
- Flights from Appleton (ATW) to Greenville (GSP)
- Flights from Asheville (AVL) to Greenville (GSP)
- Flights from Boca Raton (BCT) to Greenville (GSP)
- Flights from Hartford (BDL) to Greenville (GSP)
- Flights from Broomfield (BJC) to Greenville (GSP)
- Flights from Branson (BKG) to Greenville (GSP)
- Flights from Nashville (BNA) to Greenville (GSP)
- Flights from Boston (BOS) to Greenville (GSP)
- Flights from Burlington (BTV) to Greenville (GSP)
- Flights from Buffalo (BUF) to Greenville (GSP)
- Flights from Akron (CAK) to Greenville (GSP)
- Flights from Charleston (CHS) to Greenville (GSP)
- Flights from Clarksburg (CKB) to Greenville (GSP)
- Flights from Clarks Point (CLP) to Greenville (GSP)
- Flights from Charlotte (CLT) to Greenville (GSP)
- Flights from Columbia (COU) to Greenville (GSP)
- Flights from Mosinee (CWA) to Greenville (GSP)
- Flights from Dallas (DAL) to Greenville (GSP)
- Flights from Dayton (DAY) to Greenville (GSP)
- Flights from Denver (DEN) to Greenville (GSP)
- Flights from Dallas (DFW) to Greenville (GSP)
- Flights from Dalian (DLC) to Greenville (GSP)
- Flights from Dakar (DSS) to Greenville (GSP)
- Flights from Panama City (ECP) to Greenville (GSP)
- Flights from Frankfurt (FRA) to Greenville (GSP)
- Flights from Fort Smith (FSM) to Greenville (GSP)
- Flights from Fort Wayne (FWA) to Greenville (GSP)
- Flights from Guayaquil (GYE) to Greenville (GSP)
- Flights from Houston (HOU) to Greenville (GSP)
- Flights from Huntsville (HSV) to Greenville (GSP)
- Flights from New Haven (HVN) to Greenville (GSP)
- Flights from Jacksonville (JAX) to Greenville (GSP)
- Flights from Sitia (JSH) to Greenville (GSP)
- Flights from Kailua-Kona (KOA) to Greenville (GSP)
- Flights from Los Angeles (LAX) to Greenville (GSP)
- Flights from Lihue (LIH) to Greenville (GSP)
- Flights from Liberia (LIR) to Greenville (GSP)
- Flights from Lynchburg (LYH) to Greenville (GSP)
- Flights from Orlando (MCO) to Greenville (GSP)
- Flights from Meridian (MEI) to Greenville (GSP)
- Flights from Melbourne (MLB) to Greenville (GSP)
- Flights from Monroe (MLU) to Greenville (GSP)
- Flights from Morristown (MMU) to Greenville (GSP)
- Flights from Marion (MWA) to Greenville (GSP)
- Flights from Nairobi (NBO) to Greenville (GSP)
- Flights from Jacksonville (OAJ) to Greenville (GSP)
- Flights from Atlanta (PDK) to Greenville (GSP)
- Flights from Portland (PDX) to Greenville (GSP)
- Flights from Philadelphia (PHL) to Greenville (GSP)
- Flights from Phoenix (PHX) to Greenville (GSP)
- Flights from Laurel (PIB) to Greenville (GSP)
- Flights from Phnom Penh (PNH) to Greenville (GSP)
- Flights from Providence (PVD) to Greenville (GSP)
- Flights from Rockford (RFD) to Greenville (GSP)
- Flights from Richmond (RIC) to Greenville (GSP)
- Flights from Roanoke (ROA) to Greenville (GSP)
- Flights from San Antonio (SAT) to Greenville (GSP)
- Flights from Louisville (SDF) to Greenville (GSP)
- Flights from Seattle (SEA) to Greenville (GSP)
- Flights from Orange County (SNA) to Greenville (GSP)
- Flights from Tampa (TPA) to Greenville (GSP)
- Flights from Tulsa (TUL) to Greenville (GSP)
- Flights from Thief River Falls (TVF) to Greenville (GSP)
- Flights from Fort Walton Beach (VPS) to Greenville (GSP)
- Flights from Fayetteville (XNA) to Greenville (GSP)
- Flights from Calgary (YYC) to Greenville (GSP)
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.