$269 Cheap flight deals from Boston (BOS) to Prestonsburg (LEX)
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
Airfares from $269 One Way, $285 Round Trip from Boston to Prestonsburg
Prices starting at $285 for return flights and $269 for one-way flights to Prestonsburg were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Prestonsburg economy flight packages
21c Museum Hotel Lexington
Jul 2 - Jul 5
Boston (BOS) to Lexington (LEX)
Reviewed on May 8, 2026
Capital Plaza Hotel
Jul 12 - Jul 18
Boston (BOS) to Lexington (LEX)
Reviewed on Apr 21, 2026
The St. Clair
Jul 12 - Jul 18
Boston (BOS) to Lexington (LEX)
Reviewed on Oct 20, 2025
More About Flying To Prestonsburg from Boston
Route Information for Flights from Boston to Prestonsburg
Origin Airport IATA Code | BOS |
|---|---|
Destination Airport IATA Code | LEX |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Boston to Prestonsburg
Getting a spectacularly low fare on Boston to Prestonsburg flights is always possible when you use Orbitz as your personal travel planner. Orbitz is your essential travel resource for low cost flights from Boston to Prestonsburg, discount hotel accommodations, cheap car rentals, and more.
Research and Book Boston to Prestonsburg Flights on the Go
Our free cutting-edge mobile apps for iPad, Android, and iPhone make it easy to find the best fares when researching and booking flights from Boston to Prestonsburg. You can also use the apps to check your flight status, find baggage claims details, and get exclusive mobile discount rates on car rentals and hotels.
Earn Miles and Points for Your Frequent Flyer Program
Build up points or miles for your frequent flyer plan with qualifying Boston to Prestonsburg flights. Simply add your frequent flyer number when booking your domestic or international flights or enter the numbers in your Orbitz account profile to automatically add them to your bookings.
Flight Alerts Take the Hassle out of Travel
You can get email, SMS text, or voicemail updates regarding any major changes to your flights from Boston to Prestonsburg. These free alerts can also be sent to as many as six additional contacts, ensuring that your friends, colleagues, or family are aware of changes to your arrival time.
Stay in Your Budget and Still Get Great Accommodations
Orbitz shoppers can access affordable vacation packages and have the option of booking their departure and arrival flights through different airlines, making travel less costly and more convenient. The best prices on flights from Boston to Prestonsburgare always found on Orbitz.
Flights from Boston
- Boston to Orlando
- Boston to Chicago
- Boston to Los Angeles
- Boston to London
- Boston to Miami
- Boston to New York
- Boston to Paris
- Boston to Atlanta
- Boston to Toronto
- Boston to Houston
- Boston to Dallas
- Boston to Rome
- Boston to Montreal
- Boston to Madrid
- Boston to Detroit
- Boston to Buenos Aires
- Boston to São Paulo
- Boston to Beijing
- Boston to Kansas City
- Boston to Berlin
Prestonsburg Airports
More Destinations
- Flights from Fairbanks to Winchester
- Flights from Wilmington to Winchester
- Flights from Las Vegas to Winchester
- Flights from Minneapolis - St. Paul to Winchester
- Flights from Seoul to Winchester
- Flights from Abilene to Winchester
- Flights from Omaha to Winchester
- Flights from Oakland to Winchester
- Flights from Pensacola to Winchester
- Flights from Allentown to Winchester
- Flights from Birmingham to Winchester
- Flights from Huntsville to Winchester
- Flights from Colorado Springs to Winchester
- Flights from Tampa to Winchester
- Flights from San José to Winchester
- Flights from Biloxi to Winchester
- Flights from Stuttgart to Winchester
- Flights from Tampico to Winchester
- Flights from Salisbury to Winchester
- Flights from Casablanca to Winchester
- Flights from Covington to London
- Flights from Shanghai to Slade
- Flights from Whitefish to Paintsville
- Flights from Atlanta to Paintsville
- Flights from Austin to Paintsville
- Flights from Calgary to Paintsville
- Flights from Chicago to Paintsville
- Flights from Dallas to Paintsville
- Flights from Houston to Paintsville
- Flights from London to Paintsville
- Flights from Miami to Paintsville
- Flights from Minneapolis - St. Paul to Paintsville
- Flights from Ottawa to Paintsville
- Flights from Seattle to Paintsville
- Flights from Osaka to Paintsville
- Flights from Monterey to Paintsville
- Flights from Oklahoma City to Paintsville
- Flights from Cedar Rapids - Iowa City to Paintsville
- Flights from Mobile to Paintsville
- Flights from Williamsport to Paintsville
- Flights from Bergerac to Pikeville
- Flights from Flagstaff to Pikeville
- Flights from Calgary to Pikeville
- Flights from Detroit to Pikeville
- Flights from Phoenix to Pikeville
- Flights from Portland to Pikeville
- Flights from Raleigh to Pikeville
- Flights from Salt Lake City to Pikeville
- Flights from San Antonio to Pikeville
- Flights from Rome to Pikeville
- Flights from Brisbane to Pikeville
- Flights from Hartford to Pikeville
- Flights from Telluride to Pikeville
- Flights from Hondarribia to Pikeville
- Flights from Laredo to Pikeville
- Flights from Mason City to Pikeville
- Flights from Abilene to Pikeville
- Flights from Pucallpa to Pikeville
- Flights from Greenville to Pikeville
- Flights from Webb City to Pikeville
- Flights from Sidney to Pikeville
- Flights from Sleetmute to Pikeville
- Flights from Tyler to Pikeville
- Flights from Hamilton to Pikeville
- Flights from Forest Hill to Pikeville
- Flights from Martinsburg to Pikeville
- Flights from Burlington to Pikeville
- Flights from Atlantic City to Pikeville
- Flights from Tulsa to Pikeville
- Flights from South Bend to Pikeville
- Flights from Daytona Beach to Pikeville
- Flights from Sarasota to Pikeville
- Flights from Fort Myers to Pikeville
- Flights from Little Rock to Pikeville
- Flights from Montgomery to Pikeville
- Flights from Lansing to Pikeville
- Flights from Savannah to Pikeville
- Flights from Newport News to Pikeville
- Flights from Charleston to Pikeville
- Flights from Valdosta to Pikeville
- Flights from Con Son to Pikeville
- Flights from Meridian to Pikeville
- Flights from Greenville to Pikeville
- Flights from Andoy to Pikeville
- Flights from Boscobel to Pikeville
- Flights from Nowy Dwor Mazowiecki to Pikeville
- Flights from Aguascalientes to Pikeville
- Flights from West Harrison to Pikeville
- Flights from Akron (CAK) to Pikeville (PVL)
- Flights from Hancock (CMX) to Pikeville (PVL)
- Flights from Dallas (DFW) to Pikeville (PVL)
- Flights from Goiania (GYN) to Pikeville (PVL)
- Flights from Iasi (IAS) to Pikeville (PVL)
- Flights from Los Angeles (LAX) to Pikeville (PVL)
- Flights from London (LHR) to Pikeville (PVL)
- Flights from Kansas City (MCI) to Pikeville (PVL)
- Flights from Mana (MNF) to Pikeville (PVL)
- Flights from Roswell (ROW) to Pikeville (PVL)
- Flights from Roervik (RVK) to Pikeville (PVL)
- Flights from St. Cloud (STC) to Pikeville (PVL)
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.