Bald cypress trees with very young needles stand at the edge of Lake Marion in the Santee National Wildlife Refuge in Summerton, South Carolina.; Shutterstock ID 620988272; Purchase Order: -

Hotels near Santee National Wildlife Refuge

Name: Comfort Inn & Suites Santee
Price range: $114 total

Search over 385 hotels from $83

Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels

Save 10% or more on select hotels with Insider Prices

Book on the app to instantly earn 5% on 350,000+ hotels

Jan 23 - Jan 24

Tonight

Jan 24 - Jan 25

Tomorrow night

Featured Hotels near Santee National Wildlife Refuge

2.2 mi from Santee National Wildlife Refuge

$192 nightly

$213 total

Jan 26 - Jan 27

Total with taxes and fees

Guests staying at Country living lake style near Santee have access to laundry facilities, barbecue grills, and a garden.

Kitchen

Washer

Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6

2.27 mi from Santee National Wildlife Refuge

$153 nightly

$170 total

Jan 26 - Jan 27

Total with taxes and fees

At this cabin, guests have access to features like laundry facilities.

Free Cancellation

Reserve now, pay when you stay

4.36 mi from Santee National Wildlife Refuge

$124 nightly

$138 total

Feb 1 - Feb 2

Total with taxes and fees

At Hampton Inn Santee-I-95, guests have access to a 24-hour gym, free WiFi in public areas, and conference space. If you drive, put free parking to good use. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a 24-hour business center, a seasonal outdoor pool, and free newspapers.

Free Cancellation

Reserve now, pay when you stay

4.36 mi from Santee National Wildlife Refuge

$119 nightly

$132 total

Jan 29 - Jan 30

Total with taxes and fees

Guests staying at Best Western Plus Santee Inn enjoy an outdoor pool, a gym, and free WiFi in public areas. If you drive, put free parking to good use. The 24-hour front desk has staff always at the ready. If you like to take your furry friend along on your adventures, this pet-friendly property offers an off-leash area. Additional amenities include conference space, a business center, and free newspapers.

Fairfield Inn & Suites by Marriott Santee

Free Cancellation

Reserve now, pay when you stay

4.36 mi from Santee National Wildlife Refuge

$121 nightly

$134 total

Feb 2 - Feb 3

Total with taxes and fees

Guests staying at Fairfield Inn & Suites by Marriott Santee enjoy an outdoor pool, a gym, and free WiFi in public areas. You can put free parking to good use if you drive. Front-desk staff can answer questions 24/7, and assist with dry cleaning/laundry, securing valuables, and luggage storage. If you like to take your furry friend along on your adventures, this pet-friendly property offers an off-leash area. Additional amenities include conference space, a business center, and coffee/tea in a common area.

Free Cancellation

Reserve now, pay when you stay

4.44 mi from Santee National Wildlife Refuge

$107 nightly

$119 total

Feb 2 - Feb 3

Total with taxes and fees

At Tru By Hilton Santee, guests enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. If you drive, put free parking to good use. The 24-hour front desk has staff always at the ready. This hotel also has a 24-hour business center.

Free Cancellation

4.45 mi from Santee National Wildlife Refuge

$112 nightly

$124 total

Feb 8 - Feb 9

Total with taxes and fees

At Holiday Inn Santee by IHG, guests enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. Free parking is available if you drive. The 24-hour front desk has staff standing by to help with luggage storage and securing valuables. Other amenities at this golf hotel include meeting rooms, conference space, and a business center.

Free Cancellation

Reserve now, pay when you stay

4.48 mi from Santee National Wildlife Refuge

$75 nightly

$83 total

Jan 25 - Jan 26

Total with taxes and fees

At Baymont by Wyndham Santee, guests have access to free WiFi in public areas, coffee in a common area, and express check-in. You can put free parking to good use if you drive. The 24-hour front desk has multilingual staff ready to help with concierge services, and answer any questions about the area. Additional amenities include express check-out and a vending machine.

Free Cancellation

Reserve now, pay when you stay

4.49 mi from Santee National Wildlife Refuge

$103 nightly

$114 total

Feb 1 - Feb 2

Total with taxes and fees

Renovated in 2023, Comfort Inn & Suites Santee offers a gym, free WiFi in public areas, and a business center. You can put free parking to good use if you drive. The 24-hour front desk has multilingual staff ready to help secure valuables, and answer any questions about the area. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and a computer station.

Pool

Breakfast included

Don't see what you're looking for?

See all available properties in Santee National Wildlife Refuge

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santee National Wildlife Refuge Hotels

Orbitz makes it easy to find the best Santee National Wildlife Refuge hotel deals for your trip. With an outstanding selection, easy-to-use search tools and descriptive hotel profiles, you'll find Santee National Wildlife Refuge hotel deals in a wink..

Great selection of hotels in Santee National Wildlife Refuge

Whether you're searching for hotels in Santee National Wildlife Refuge on business, or hunting for a family getaway, Santee National Wildlife Refuge hotel options are only a click away. Find hotels in Santee National Wildlife Refuge with the location, star-rating and facilities you need. Narrow your search results even further by star rating, hotel chain and amenities, such as free parking, babysitting services, or fitness centers. And with area maps, you can view Santee National Wildlife Refuge hotels close you are to the airport and nearby attractions.

Santee National Wildlife Refuge hotel reviews, photos and virtual tours

Thanks to photos and virtual tours, you can look before you book your Santee National Wildlife Refuge hotel reservation. Check out Santee National Wildlife Refuge hotel properties using interactive tools which allow you view hotel rooms, common areas and key features. On Orbitz, you can also learn more about hotels in Santee National Wildlife Refuge with unbiased reviews from verified Santee National Wildlife Refuge hotel guests. We ask guests to offer candid feedback on services, comfort, location, value and amenities.

Grab Santee National Wildlife Refuge hotel deals and special offers

Orbitz works around the clock to find exclusive offers and Santee National Wildlife Refuge hotel deals, just for you. Sign up for deals by e-mail where you'll get first crack at money-saving extras like promo codes, resort credits, free nights and more. You can also "Like" Orbitz on Facebook and follow us on Twitter to receive up-to-the-minute news on hotel discounts, giveaways and more.

24/7 support with Santee National Wildlife Refuge hotel reservations

When it comes to finding hotels in Santee National Wildlife Refuge, an Orbitz specialist can help you find the property right for you. Chat live or call 1-800-454-3743 any time for help booking your hotels in Santee National Wildlife Refuge. Our team of experts can help you pinpoint Santee National Wildlife Refuge hotels options suited to your tastes and budget.

Forget Orbitz change or cancel fees on Santee National Wildlife Refuge hotels

On Orbitz, Santee National Wildlife Refuge hotel deals mean flexibility. If you need to change your Santee National Wildlife Refuge hotel reservations, or cancel your stay, Orbitz doesn't charge cancel or change fees. Orbitz also offers great selection on airline tickets, vacation packages, and car rental deals to so you can plan your trip to Santee National Wildlife Refuge all in one place.

Santee National Wildlife Refuge hotels essential information

Accommodation	385 hotels
Lowest Price	$83
Highest Price	$213
Popular hotels	Baymont by Wyndham Santee, Tru By Hilton Santee, Hampton Inn Santee-I-95, Comfort Inn & Suites Santee, Fairfield Inn & Suites by Marriott Santee, Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6 , Best Western Plus Santee Inn, Holiday Inn Santee by IHG, Country living lake style near Santee