$348 Cheap flights to São Tomé and Príncipe

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Cheap flights to São Tomé and Príncipe from $348 One Way, $350 Round Trip

$350 return flights and $348 one-way flights to São Tomé and Príncipe were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Oct 21 - Wed, Oct 28
ACC
Accra
TMS
São Tomé Island
$350 Roundtrip, found 5 days ago
$350
Roundtrip
found 5 days ago
Select TAP Portugal flight, departing Wed, Oct 21 from Accra to São Tomé Island, returning Wed, Oct 28, priced at $350 found 5 days ago
Wed, May 13 - Wed, May 20
LIS
Lisbon
TMS
São Tomé Island
$681 Roundtrip, found 13 hours ago
$681
Roundtrip
found 13 hours ago
Select TAP Portugal flight, departing Wed, May 13 from Lisbon to São Tomé Island, returning Wed, May 20, priced at $681 found 13 hours ago
Sun, Mar 29 - Wed, Apr 1
LIS
Lisbon
TMS
São Tomé Island
$685 Roundtrip, found 7 hours ago
$685
Roundtrip
found 7 hours ago
Select TAAG Angola Airlines flight, departing Sun, Mar 29 from Lisbon to São Tomé Island, returning Wed, Apr 1, priced at $685 found 7 hours ago
Thu, Jan 1 - Wed, Jan 7
ACC
Accra
TMS
São Tomé Island
$1,117 Roundtrip, found 1 day ago
$1,117
Roundtrip
found 1 day ago
Select ASKY flight, departing Thu, Jan 1 from Accra to São Tomé Island, returning Wed, Jan 7, priced at $1,117 found 1 day ago
Fri, Apr 17 - Fri, Apr 24
ORD
Chicago
TMS
São Tomé Island
$1,266 Roundtrip, found 5 days ago
$1,266
Roundtrip
found 5 days ago
Select TAP Portugal flight, departing Fri, Apr 17 from Chicago to São Tomé Island, returning Fri, Apr 24, priced at $1,266 found 5 days ago
Fri, Feb 27 - Fri, Mar 6
IAD
Washington
TMS
São Tomé Island
$1,452 Roundtrip, found 2 days ago
$1,452
Roundtrip
found 2 days ago
Select TAP Portugal flight, departing Fri, Feb 27 from Washington to São Tomé Island, returning Fri, Mar 6, priced at $1,452 found 2 days ago
Fri, May 1 - Sun, May 10
EWR
New York
TMS
São Tomé Island
$1,601 Roundtrip, found 3 days ago
$1,601
Roundtrip
found 3 days ago
Select Air Canada flight, departing Fri, May 1 from New York to São Tomé Island, returning Sun, May 10, priced at $1,601 found 3 days ago
Thu, Oct 1 - Wed, Oct 7
BOS
Boston
TMS
São Tomé Island
$1,667 Roundtrip, found 1 day ago
$1,667
Roundtrip
found 1 day ago
Select Lufthansa flight, departing Thu, Oct 1 from Boston to São Tomé Island, returning Wed, Oct 7, priced at $1,667 found 1 day ago

Deals For This Weekend's Flights

OriginDestinationTravel DatesFlights From*
ACCSão ToméJanuary 2 to January 4$610
LISSão ToméJanuary 2 to January 11$1,794
*Prices include taxes and fees

Find The Perfect Hotel For After Your Flight

Our Top São Tomé and Príncipe Apartment Hotels

Sweet Guest House

Sweet Guest House

2.5 out of 5
Vila Dolores n. 087 São Tomé
Book a stay at this spa guesthouse in São Tomé. Enjoy free WiFi, free parking, and a full-service spa. Popular attractions Cloçon Téla Chocolate Factory and ...
8.6/10 Excellent! (44 reviews)
A very clean comfortable good value stay 10 mins walk from the centre of town. There is good WiFi and a laundry and small shop across the road.

Reviewed on Jun 27, 2024

Get rates
Opens in a new windowSweet Guest House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Score Epic São Tomé and Príncipe Accommodation Deals

Pestana São Tomé

Pestana São Tomé

5 out of 5
Avenida Marginal 12 De Julho São Tomé
Fully refundableReserve now, pay when you stay
$206 nightly
The price is $237 total per night from Jan 4 to Jan 5
$237 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Book a stay at this luxury hotel in São Tomé. Enjoy free WiFi, free parking, and a beach locale. Popular attractions Estadio Nacional 12 de Julho and Cloçon ...
8/10 Very Good! (78 reviews)
Wonderful stay, great staff, easy, relaxing delightful.

Reviewed on Dec 9, 2025

Opens in a new windowPestana São Tomé
Hotel Central

Hotel Central

3.5 out of 5
Rua de Angola São Tomé São Tomé
Book a stay at this business-friendly hotel in São Tomé. Enjoy free breakfast, free parking, and an airport shuttle (surcharge). Popular attractions Cloçon Téla ...
8/10 Very Good! (24 reviews)
On my last night, I was locked out and couldn't open the outside door to enter the hotel. I tried to contact the hotel using the phone number provided on Expedia, but it wasn't updated. As a result, I had to stay at a friend's house for the night.

Reviewed on Nov 7, 2024

Get rates
Opens in a new windowHotel Central
Omali São Tomé – Principe Collection

Omali São Tomé – Principe Collection

4 out of 5
Praia Lagarto São Tomé
$197 nightly
The price is $230 total per night from Jan 4 to Jan 5
$230 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Book a stay at this beach resort in São Tomé. Enjoy free breakfast, free WiFi, and free parking. Popular attractions São Sebastião Museum and Cloçon Téla Chocolate ...
9.4/10 Exceptional! (62 reviews)
Staff was very friendly. Food was excellent. Room was clean and well kept.

Reviewed on Dec 4, 2025

Opens in a new windowOmali São Tomé – Principe Collection
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Hotel Praia

Hotel Praia

3.5 out of 5
Praia Lagarto - Cx. Postal 61 São Tomé
$149 nightly
The price is $175 total per night from Jan 10 to Jan 11
$175 total
Jan 10 - Jan 11, 2026
Total with taxes and fees
Book a stay at this business-friendly hotel in São Tomé. Enjoy free breakfast, free WiFi, and free parking. Popular attractions São Sebastião Museum and Cloçon ...
7.2/10 Good! (18 reviews)
Pros: Room is very spacious and clean. Common areas also nice and generally I enjoyed a quiet atmosphere. Staff is nice, food is good. Cons: They did not honor the complementary airport transfer that is announced on line, they arranged a private taxi that charged me 20 US Dollars (for a 4 minute ...

Reviewed on Dec 6, 2023

Opens in a new windowHotel Praia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in São Tomé and Príncipe

Bom Bom – Principe Collection

Bom Bom – Principe Collection

4 out of 5
Bom Bom Island Príncipe Island
$562 nightly
The price is $646 total per night from Jan 24 to Jan 25
$646 total
Jan 24 - Jan 25, 2026
Total with taxes and fees
Book a stay at this beach hotel in Príncipe Island. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Margarida Beach and Sundy Plantation ...
8.4/10 Very Good! (6 reviews)
Best Place Ever!
BomBom is simply magical. The natural beauty is unrivaled only by the friendliness and kindness of the staff. Coming from the US without any Portuguese speaking skills was scary but the people here made it comfortable immediately. Would give BomBom 100 out of 100 stars!

Reviewed on Aug 8, 2019

Opens in a new windowBom Bom – Principe Collection
Somos Hotel Avenida

Somos Hotel Avenida

3 out of 5
Avenida da Independencia São Tomé São Tomé
Book a stay at this business-friendly hotel in São Tomé. Enjoy free breakfast, free parking, and room service. Popular attractions Estadio Nacional 12 de Julho ...
Good
Good

Reviewed on Aug 29, 2018

Get rates
Opens in a new windowSomos Hotel Avenida
Roça Sundy – Principe Collection

Roça Sundy – Principe Collection

4 out of 5
Santo Antonio, Sundy Estate Príncipe Island
$482 nightly
The price is $555 total per night from Jan 24 to Jan 25
$555 total
Jan 24 - Jan 25, 2026
Total with taxes and fees
Book a stay at this business-friendly hotel in Príncipe Island. Enjoy free breakfast, free parking, and a free airport shuttle. Popular attractions Sundy Plantation ...
7.8/10 Good! (20 reviews)
Lovely island; hotel staff is disappointing
Príncipe is a beautiful place. However, this hotel doesn’t offer much beyond a clean room. Food is subpar and uninteresting, activities are difficult to organize, and staff - despite being largely well-intentioned - is useless. Separately, I had a horrible time checking out. The assistant manager, ...

Reviewed on Apr 21, 2019

Opens in a new windowRoça Sundy – Principe Collection
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Pestana Miramar São Tomé

Pestana Miramar São Tomé

3 out of 5
Avenida Marginal 12 De Julho São Tomé
Fully refundableReserve now, pay when you stay
$151 nightly
The price is $173 total per night from Jan 4 to Jan 5
$173 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Book a stay at this beach resort in São Tomé. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Estadio Nacional 12 de Julho and São ...
7.2/10 Good! (45 reviews)
Very helpful and accommodating staff

Reviewed on Jun 7, 2024

Opens in a new windowPestana Miramar São Tomé
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

Economy

Chevrolet Spark or similar
  • 4 people
Chevrolet Spark
Economy Chevrolet Spark

Compact

Ford Focus or similar
  • 4 people
Ford Focus
Compact Ford Focus

Midsize

Toyota Corolla or similar
  • 5 people
Toyota Corolla
Midsize Toyota Corolla

SUV

Jeep Compass or similar
  • 5 people
Jeep Compass
SUV Jeep Compass

São Tomé and Príncipe

If you are looking for affordable flights to São Tomé and Príncipe, look no further. Orbitz offers discounted rates to many destinations.

Bargain flights to São Tomé and Príncipe now available

As you review your budget and travel plans, consider the low fares Orbitz offers on São Tomé and Príncipe flights. With Orbitz, booking flights to São Tomé and Príncipe is easy and the lowest prices are guaranteed.

Easy self-help service offered

Orbitz offers cutting edge mobile tools that allow you to review and make bookings from your Android or iPhone mobile device with a simple application. You can easily and conveniently update your information or book your trip using this service. You are also able to obtain information on affordable hotel packages and receive frequent flight updates. You will receive confirmation of bookings or reservations made using the mobile service on the same day of the request. Change details or receive updates on your São Tomé and Príncipe flights by visiting the Orbitz site or mobile application.

Orbitz looks after you

Orbitz ensures that you are kept informed with up-to-date flight information, providing feedback to up to six contact numbers to ensure that everyone receives the feedback. In addition to providing the discounted deals on São Tomé and Príncipe flights, Orbitz is also able to structure a package based on your needs for activities, car hire and accommodations.

Traveler profile updates

After booking your São Tomé and Príncipe flights, you may access your account profile on the Orbitz site and update your frequent flyer or loyalty membership details. This information will remain on the system and will be available for you to access when you make any future bookings with Orbitz.

Frequently asked questions

Which airlines fly to Sao Tome and Principe?
With 18 airlines ready to whisk you off to Sao Tome and Principe, finding a suitable flight will be a cinch. Lock in a ticket with one of these top carriers that offer services to Sao Tome Intl. Airport (TMS):

  • TAP Air Portugal - 4 flights to Sao Tome and Principe per month
  • TAAG Angola Airlines - 0 flights to Sao Tome and Principe per month
  • STP Airways - 0 flights to Sao Tome and Principe per month

What is the best airport to fly to in Sao Tome and Principe?
Jet into Sao Tome Intl. Airport (TMS), the main gateway to Sao Tome and Principe. Booking your flight to this region doesn't get much easier.
How much is a flight to Sao Tome and Principe?
This week, prices hovered between $350 and $1,794 for a return fare to Sao Tome and Principe. One-way fares from Lisbon (LIS) dropped as low as just $348 during the same time period.
How to book the cheapest flight to Sao Tome and Principe?
With some of the most exciting flight deals around, you'll always jet for less with Orbitz. The following useful tips will help you pick up cheap flights to Sao Tome and Principe — and leave you with more money to play with:

  • Departing from or arriving at other airports can sometimes help you save on airfares. Type in your preferred departure and arrival points. Next, click on the 'Nearby airports' function below the form fields to compare your options.
  • If your travel plans aren't set in concrete, click on the 'Show flexible dates' option to compare flight deals for a selection of departure dates. If you find a suitable cheaper fare, go with it.
  • You can also hit the 'Show options' link to filter results for your preferred carrier, seating class, nonstop flights and refundable flights. Under 'Sort & Filter' to the left, you can even choose the time of day you'd prefer to fly.
  • The early bird gets the best deals, so book as soon as you've worked out your travel dates. The most affordable fares go like hotcakes and prices rise as the departure date gets closer.
  • Bundle your hotels, flights and car rentals into a competitive package deal. Save your money for things you're really excited about, like exploring every corner of Sao Tome and Principe.
  • Flying during peak season means expensive airfares. Try to avoid traveling over popular dates, such as Thanksgiving, New Year's Eve and Easter.

What is the best time to book a flight to Sao Tome and Principe?
Generally speaking, January is the cheapest month to book your airfare. This is followed by February and August. Keep this in mind while you search for a cheap flight to Sao Tome and Principe.
What day of the week is the cheapest to book a flight to Sao Tome and Principe?
To find a fantastic flight deal, make a booking on a Tuesday, Wednesday or Saturday. These are generally the cheapest days of the week to purchase tickets to Sao Tome and Principe.
What is the cheapest day of the week to fly to Sao Tome and Principe?
According to Orbitz data from 2020, you ought to kick off your trip on a Monday to score cheap flights to Sao Tome and Principe. Next most inexpensive day? Tuesday. Saturday will cost the most. So, consider departing early in the week if you'd love to book a wallet-friendly fare and stretch your travel budget.
What is the cheapest month to fly to Sao Tome and Principe?
According to Orbitz data, it's better to fly out in August. This is generally a great month to land cheap flights to Sao Tome and Principe. Be aware that the most expensive time to fly is in June.
Which airlines allow free cancellation?
We understand that plans can change and flexibility matters. That's why you can search for flights that have free cancellation and no change fees on Orbitz. Just click on "Filter by flexible change policies" and we'll find you fares more flexible than candy in a car on a hot day!
What do I need for the flight to Sao Tome and Principe?
The trick to having a smooth and stress-free flight is to plan ahead. Here are a couple of tips to keep in mind before you depart:

  • Nothing is more important than your travel documents. Which to bring and how many depend on whether you're traveling international or domestic. Be sure to check with your airline. In both cases, you'll need to present photo identification.
  • Take a good book or a tablet filled with your favorite TV series — it'll help to pass time on your journey to Sao Tome and Principe. Or if you're hoping to take a snooze, an eye mask will shield you from those bright cabin lights.
  • Cabin temperatures can quickly change, so it's wise to bring an extra layer. Also consider compression socks. They can help prevent swelling and blood clots.

How many direct flights are there to Sao Tome and Principe?
With 6 flights traveling straight to Sao Tome and Principe every month, finding one to suit your itinerary will be a snap. STP Airways, TAP Portugal and TAAG are among the major carriers that provide nonstop services.
How do I get cheap first-class/business deals to Sao Tome and Principe?
If you think a business or first-class fare is beyond your reach, think again. Here are some terrific tips to help you pick up a premium flight to Sao Tome and Principe for a whole lot less:

  • Flexibility isn't just useful for your yoga. Have some room to move around your travel dates so you can snap up cheaper airfares when a sale pops up.
  • Search for a budget airline that has business-class seats. They often come with extra legroom and a glass of bubbly — and a nicer price.
  • Bid for an upgrade in online auctions or upgrade with loyalty points.

What is the best time to go to São Tomé and Príncipe?
There's no right or wrong time to visit São Tomé and Príncipe, but March, August and September are the liveliest months. As with most of the Northern Hemisphere, the summer season kicks off June 20. If you'd sooner spend your days in a light T-shirt than a heavy winter jacket, this time of year would be ideal for you. Expect average daily highs of 80 ºF and nightly lows around 75 ºF.
Travel tips for Sao Tome and Principe

  • Sao Tome and Principe has dozens of wonderful attractions and Market is one of them. Pick up a car rental and head there at your own speed.
  • Sao Tome Island offers tons of one-of-a-kind experiences and is a top place to kick off your vacation. Whether you're into art, cafés, restaurants or something else, this city will keep you entertained.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.