Clemson Vacation Packages

The expert team at Orbitz will help combine your flights and hotels to save time and money. Just choose an option and get packing for that epic adventure to Clemson. What are the benefits? Package your airfares, hotels, rental cars and experiences with us and you can save up to $374! With 500 partner airlines and no less than 500,000 hotels globally, you have the freedom to decide who you'll fly with and where you'll stay! With endless options to pick and choose from, our packages will help you design that vacation you're dreaming about.

Where is Clemson?

Your accommodation is booked and you've checked out the weather for Clemson. But do you know exactly where you're headed? We'll show you! You'll discover it approximately 110 miles northwest of Columbia, the state capital of South Carolina, and around 4 miles southwest of Central. You can forget about the star attractions — it's the locals that make a place tick. In this part of South Carolina, you'll find 14,000 of them.

Car Rentals in Clemson

Your vacation begins with car rentals in Clemson. Whether you’d love to veer off the standard tourist trail or just crave the convenience of having your own wheels, Orbitz will help you find the keys to your ride. Get off the plane, jump into a car and kick off your adventure as soon as you hit the tarmac at Anderson County Regional Airport. You can collect your keys at Enterprise, located at 4112 Clemson Blvd, 15 miles from the terminal. There are no rental outlets in the center of the city. So if you're looking into renting a car in Clemson, you'll need to travel to a nearby neighborhood. Located at 204 By Pass 123 in Seneca is Enterprise. Drop by and you'll be driving around in no time.

Where to stay in Clemson – Hotel Accommodation

Orbitz can help you lock in a decent room in this destination, but you'll need to act fast! Currently, you'll find only 8 hotels in Clemson. Check out the great amenities at the Hampton Inn Clemson and Holiday Inn Express & Suites Clemson.

Nearest Airports to Clemson

Are you planning to fly into Greenville-Spartanburg International Airport (GSP)? You'll be taking in the best of Clemson before you know it! It's located 40 miles to the northeast of Clemson's center.

Popular Places to Visit Near Clemson

Checked out all the highlights in Clemson itself? If you have a couple more days on your hands, there is heaps more available in the surrounding area. You might be unaware that you're only 25 miles away from Greenville. It's the perfect base point to access Falls Park on the Reedy. This attraction is loved by travelers and locals alike.

No Cancellation Fees

Pulled out your passport, booked your adventure but now you can't go? Don't worry too much — we make canceling simple by not charging you a fee.^ Act fast and your selected airline and hotel might do the same!

Top Clemson vacation package deals

Price found within the past 48 hours. Click for updated prices.

2.5-star property

Best Western Plus Clemson Hotel & Conference Center

8.2/10 Very Good! (1,013 reviews)

Jan 15 - Jan 20

5 night stay

Seattle (SEA) to Greenville (GSP)

American Airlines • Non-stop roundtrip • Coach

$543

per person

found 1 day ago

on our arrival we were early, we were told we had to pay for an early check in fee, we didn’t have a problem with that if the lady was nice about it and looked at us and welcomed us to the hotel. instead she sat at the desk didn’t look at us and we abrupt about it. Then we went to take a shower and the curtain in the shower had mold all on the bottom of it. The cleaning lady was very nice about it but i had to put up the new curtain because she didn’t know how to put it up. Then that night at 10:30 the TV goes out, we had no TV until the next afternoon. Then the same thing happens with the TV before we went out for dinner. Then on top of everything the electric goes out, which we understand it wasn’t there fault, but they put out the breakfast food it was hot, they decided to take it away then the lights go back on at 8:00 and they decided to not put out any hot food but the lady that was working it decide to eat her eggs in front of everyone that she heated up. unbelievable!!! We went to use the waffle machine and the decided to not plug it in. I never seen anything like this before and this wasn’t our first time staying there and we will not be staying there moving forward.

Reviewed on Aug 12, 2025