Compare South San Diego Guest House Rentals

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Featured Guest Houses in South San Diego

El Primero Hotel

El Primero Hotel

2.5 out of 5
416 Third Avenue Chula Vista CA
Free Cancellation
Reserve now, pay when you stay
$80 nightly
The price is $88 total per night
$88 total
Dec 17 - Dec 18
Total with taxes and fees
Guests staying at El Primero Hotel enjoy free WiFi in public areas and a computer station. A stay here includes free parking. The 24-hour front desk has multilingual staff ready to assist with sightseeing, directions, and local dining recommendations.
Parking included
Free WiFi
Vineyard Hacienda

Vineyard Hacienda

3.5 out of 5
12685 Campo Rd Spring Valley CA
Free Cancellation
Reserve now, pay when you stay
$157 nightly
The price is $170 total per night
$170 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Vineyard Hacienda features a winery, an outdoor pool, and a gym. You can take advantage of free parking, along with an airport shuttle for a fee. The front desk has multilingual staff that can help with luggage storage and concierge services. Additional amenities include free WiFi in public areas, a hot tub, and a seasonal outdoor pool.
Pool
Hot Tub
Centrally Located, Private Bungalow with AC and parking space

Centrally Located, Private Bungalow with AC and parking space

San Diego CA
At this guesthouse, guests enjoy features like beach towels.
Air conditioning
Parking available
Outsite San Diego - Golden Hill

Outsite San Diego - Golden Hill

2 out of 5
1203 23rd Street San Diego CA
At Outsite San Diego - Golden Hill, guests have access to free WiFi in public areas and laundry facilities.
Free WiFi
Laundry
Point Loma retreat - 4 blocks to the Bay

Point Loma retreat - 4 blocks to the Bay

San Diego CA
Guests of this guesthouse enjoy access to a water park, laundry facilities, and a garden.
Free WiFi
Air conditioning
Crown Point On The Water: Mission Bay

Crown Point On The Water: Mission Bay

San Diego CA
$324 nightly
The price is $361 total per night
$361 total
Jan 10 - Jan 11, 2026
Total with taxes and fees
At this guesthouse, guests have access to features like laundry facilities.
Free WiFi
Laundry
Hidden King Suite with Garden, Parking - 4 Guest

Hidden King Suite with Garden, Parking - 4 Guest

La Mesa CA
At this guesthouse, guests have access to features like laundry facilities. This smoke-free guesthouse also has a garden.
Air conditioning
Parking available
Ocean Beach Casita with hot tub, Ocean views & Garage!

Ocean Beach Casita with hot tub, Ocean views & Garage!

San Diego CA
Guests of this guesthouse enjoy features like a gym, a hot tub, and an arcade/game room. Additional amenities include laundry facilities and barbecue grills.
Hot Tub
Free WiFi
Newly Built Guest Home

Newly Built Guest Home

San Diego CA
$506 nightly
The price is $563 total per night
$563 total
Jan 15 - Jan 16, 2026
Total with taxes and fees
At this guesthouse, guests have access to features like laundry facilities. This family-friendly guesthouse also has a water dispenser.
Pet friendly
Free WiFi
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in South San Diego

    Sheraton San Diego Resort

    Sheraton San Diego Resort

    1380 Harbor Island Dr San Diego CA
    $143 nightly
    The price is $165 total per night from Jan 6 to Jan 7
    $165 total
    Jan 6 - Jan 7, 2026
    Total with taxes and fees
    8.2/10 Very Good! (3,168 reviews)
    The DEXTRO Little Italy, BW Premier Collection

    The DEXTRO Little Italy, BW Premier Collection

    1617 1st Avenue San Diego CA
    $107 nightly
    The price is $124 total per night from Dec 22 to Dec 23
    $124 total
    Dec 22 - Dec 23
    Total with taxes and fees
    8.8/10 Excellent! (727 reviews)
    Legacy Resort Hotel & Spa

    Legacy Resort Hotel & Spa

    875 Hotel Circle South San Diego CA
    $152 nightly
    The price is $175 total per night from Dec 21 to Dec 22
    $175 total
    Dec 21 - Dec 22
    Total with taxes and fees
    9/10 Wonderful! (2,941 reviews)

South San Diego Guest Houses essential information

Accommodation
15 Guest Houses
Lowest Price
$88
Highest Price
$563
Popular accommodation
El Primero Hotel, Vineyard Hacienda, Centrally Located, Private Bungalow with AC and parking space, Outsite San Diego - Golden Hill, Point Loma retreat - 4 blocks to the Bay, Crown Point On The Water: Mission Bay , Hidden King Suite with Garden, Parking - 4 Guest, Ocean Beach Casita with hot tub, Ocean views & Garage!, Newly Built Guest Home

More to Explore