The Chemists’ Club Hotel

4.0 star property
Hotel with a restaurant, steps from Grand Central Terminal

Choose dates to view prices

Photo gallery for The Chemists’ Club Hotel

Deluxe Room, 1 Queen Bed, Terrace | Down comforters, in-room safe, desk, laptop workspace
Interior
Restaurant
Exterior
Interior

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Room service
  • Bar
  • Housekeeping
  • Laundry

Explore the area

View in a map
52 E 41st St, New York, NY, 10017
  • Place, 5th Avenue
    ‪1 min walk‬
  • Place, Grand Central Terminal
    ‪3 min walk‬
  • Place, Bryant Park
    ‪6 min walk‬
  • Airport, New York, NY (LGA-LaGuardia)
    ‪16 min drive‬

Room options

Classic Room, 1 King Bed

9.6 out of 10
Exceptional
(14 reviews)
  • 200 sq ft
  • Sleeps 2
  • 1 King Bed

Deluxe Room, 1 King Bed

9.4 out of 10
Exceptional
(30 reviews)
  • 300 sq ft
  • Sleeps 2
  • 1 King Bed

Deluxe Room, 1 Queen Bed

10.0 out of 10
Exceptional
(1 review)
  • 200 sq ft
  • Sleeps 2
  • 1 Queen Bed

Deluxe Room, 2 Double Beds

10.0 out of 10
Exceptional
(1 review)
  • 350 sq ft
  • Sleeps 4
  • 2 Double Beds

Deluxe Double Mobility/Hearing Accessible with Roll-In Shower

10.0 out of 10
Exceptional
(3 reviews)
  • 350 sq ft
  • Sleeps 4
  • 2 Double Beds

King Deluxe Mobility/Hearing Accessible with Roll-In Shower

10.0 out of 10
Exceptional
(1 review)
  • 350 sq ft
  • Sleeps 2
  • 1 King Bed

Junior Suite

8.6 out of 10
Excellent
(7 reviews)
  • 400 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

Deluxe Room, 1 Queen Bed, Terrace

  • 200 sq ft
  • Sleeps 2
  • 1 Queen Bed

Junior Suite King Mobility/Hearing Accessible with Transfer Shower

  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

Alchemy Suite

10.0 out of 10
Exceptional
(1 review)
  • 350 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

King Deluxe Mobility/Hearing Accessible with Tub

  • Sleeps 2
  • 1 King Bed

You may also like

About the neighborhood

New York

Located in Manhattan, The Chemists’ Club Hotel is adjacent to Grand Central Terminal and within a 5-minute walk of other popular sights like 5th Avenue. This 107-room, 4-star hotel welcomes guests with a restaurant, a 24-hour gym, and free in-room WiFi.

What's nearby

  • 5th Avenue - 1 min walk - 0.0 miles
  • Grand Central Terminal - 3 min walk - 0.2 miles
  • Bryant Park - 6 min walk - 0.4 miles
  • Empire State Building - 8 min walk - 0.5 miles
  • Broadway - 10 min walk - 0.5 miles

Getting around

  • Grand Central - 42 St. Station - 2 min walk
  • 5 Av Station (W. 42nd St.) - 4 min walk
  • LaGuardia Airport (LGA) - 27 min drive

Restaurants

  • ‪Chick-fil-A - ‬2 min walk
  • ‪Blue Bottle Coffee - ‬2 min walk
  • ‪Kona Coffee Roasters - ‬1 min walk
  • ‪Stout NYC - ‬2 min walk
  • ‪Pera Mediterranean Brasserie - ‬1 min walk

About this property

The Chemists’ Club Hotel

Hotel with a restaurant, steps from Grand Central Terminal
Guests of The Chemists’ Club Hotel enjoy features like a 24-hour gym, free WiFi in public areas, and free newspapers. The 24-hour front desk has multilingual staff ready to assist with dry cleaning/laundry and tours/tickets. This boutique hotel also has laundry facilities.
Guests can expect free WiFi and 55-inch LED TVs with cable channels. Bathrooms offer hair dryers and designer toiletries, and beds sport down comforters. Refrigerators, coffee makers, and free weekday newspapers are other standard amenities.
Recreational amenities at the hotel include a 24-hour fitness center.

The recreational activities listed below are available either on site or nearby; fees may apply.

Similar properties

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi and wired internet

Parking and transportation

  • Offsite parking within 0.2 miles (USD 65 per day)

Food and drink

  • A bar/lounge
  • A restaurant

Things to do

  • 24-hour gym

Family friendly

  • In-room crib
  • In-room refrigerator
  • Laundry facilities
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Laundry facilities

Guest services

  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)
  • Multilingual staff
  • Tour and ticket assistance

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Accessible bathtub
  • Assistive listening devices
  • Bathroom emergency pull cord
  • Braille/raised signage
  • No elevator
  • Wheelchair accessible (may have limitations)

More

  • 16 floors
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Down comforter
  • Free crib

Bathroom

  • Bathrobes
  • Bathtub or shower
  • Designer toiletries
  • Hair dryer
  • Private bathroom
  • Towels provided

Entertainment

  • 55-inch LED TV with cable channels

Food and drink

  • Coffee/tea maker
  • Electric kettle
  • Limited room service
  • Refrigerator

More

  • Air conditioning
  • Desk
  • Desk chair
  • Free weekday newspapers
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Laptop-compatible safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 3 PM; Check-in end time: anytime
Early check-in subject to availability
Early check-in fee: USD 60.00
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Late check-out subject to availability
Late check-out fee: USD 150

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • Service animals exempt from fees

Children and extra beds

  • Up to 10 kids 1 year old and younger stay free when using existing bedding
  • Free cribs/infant beds are available

Property payment types

Important information

Fees

You'll be asked to pay these charges at the property:

  • Deposit: USD 50.00 per night
  • Destination fee: USD 40.17 per accommodation, per night

These are all of the charges provided to us by the property.

Optional extras

These fees and deposits will be charged at check-in, check-out, or the time of service.

  • Offsite parking fee: USD 65 per day (0.2 mi away)
  • Early check-in fee: USD 60.00 (subject to availability)
  • Late check-out fee: USD 150 (subject to availability)

This list may not be comprehensive. Fees and deposits might not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards and cash
Noise-free guestrooms cannot be guaranteed
  • Check-in: 3 PM
  • Check-out: 11 AM
  • Minimum check-in age: 21
The front desk is open 24 hours a day.

We should mention

Details about charges, deposits, or other important information:

  • This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
  • Charges for extra guests may apply and vary depending on the property's policy.
  • A credit card for incidental charges and a government-issued photo ID may be required at check-in.
  • Special requests are subject to availability at the time of check-in and can't be guaranteed. Certain requests may come with additional charges.
  • This property accepts credit cards and cash.
  • The credit card used at check-in for incidentals must be in the name of the primary guest who made the reservation.

Additional information about polices, regulations, and more:

  • The hotel can refuse certain bookings for the purpose of group events or parties, which include pre-wedding stag/bachelor and hen/bachelorette parties.
  • Registered guests are the only ones allowed in guestrooms.
  • There are no elevators.
  • No rollaway or extra beds are available.
  • Noise-free rooms can't be guaranteed.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Dylan Hotel NYC New York
Dylan Hotel New York
Dylan New York
Hotel Dylan
Dylan Hotel New York City
Dylan New York City
Dylan NYC New York
Dylan NYC
Dylan Hotel NYC
The Chemists’ Club Hotel Hotel
The Chemists’ Club Hotel New York
The Chemists’ Club Hotel Hotel New York

Frequently asked questions

Is free cancellation available at The Chemists’ Club Hotel?

The Chemists’ Club Hotel offers free cancellation on select room rates. For additional details, review the cancellation policy on Orbitz.

How much does it cost to stay at The Chemists’ Club Hotel?

As of Dec 16, 2025, prices found for a 1-night stay for 2 adults at The Chemists’ Club Hotel on Jan 4, 2026 start from $238.54, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

What can I see close to The Chemists’ Club Hotel?

This hotel is situated in Manhattan, just steps from Grand Central Terminal, and within a 10-minute walk of 5th Avenue and Bryant Park. You'll also find Broadway and Times Square less than a mile away.

Is there parking available at The Chemists’ Club Hotel?

No, there isn't parking available at the hotel.

Does The Chemists’ Club Hotel feature a casino at the property?

No, The Chemists’ Club Hotel doesn't have a casino.

Is there an indoor pool at The Chemists’ Club Hotel?

No, there is no indoor pool at this hotel.

Is The Chemists’ Club Hotel good for couples?

Amenities that appeal to couples at this boutique hotel include a down comforter and bathrobes along with a bar.

Are there hot tubs at The Chemists’ Club Hotel?

No, this hotel doesn't have a spa tub.

Does The Chemists’ Club Hotel have a restaurant with a breakfast menu?

No, The Chemists’ Club Hotel doesn't have a restaurant that serves breakfast.

Does The Chemists’ Club Hotel allow pets to stay free of charge?

No, pets aren't allowed at The Chemists’ Club Hotel though service animals are welcome.

Are there connecting rooms at The Chemists’ Club Hotel?

No, this hotel doesn't feature connecting guestrooms.

How far is the airport from The Chemists’ Club Hotel?

The closest major airport to The Chemists’ Club Hotel is LaGuardia Airport (LGA), which is 8.7 mi away (27 minutes by car). Another top airport is Teterboro, NJ (TEB), which is located 12.3 mi away (16-minute drive).

Can I book a room with a balcony at The Chemists’ Club Hotel?

No, there aren't any guestrooms with balconies at The Chemists’ Club Hotel.

Reviews

The Chemists’ Club Hotel Reviews

9.4

Exceptional

9.8/10

Cleanliness

9.6/10

Staff & service

9.4/10

Amenities

9.6/10

Property conditions & facilities

9.6/10

Eco-friendliness
Rating 10 - Excellent. 239 out of 302 reviews
Rating 8 - Good. 42 out of 302 reviews
Rating 6 - Okay. 11 out of 302 reviews
Rating 4 - Poor. 3 out of 302 reviews
Rating 2 - Terrible. 7 out of 302 reviews

Reviews

10/10 Excellent

Amy

Stayed 2 nights in Sep 2025

6/10 Okay

Melissa

Traveled with family
Disliked: Cleanliness
Was so looking forward to our stay. The communication from the hotel before we arrived was amazing and the pictures of our room convinced us to stay with this choice over another option. When we arrived…. We were greeted and assigned a room that had a view of scaffolding and hair all over the bathroom floor. No worries they said we will move you and they did super quickly we were so grateful. Until we tried to look out the window… which was painted over ensuring minimal natural light. We were only staying for 1 night so we frankly gave up trying. If we’d been staying for longer we would have moved to our other choice. On checking out we were initially told it was our fault for booking via Expedia, and offered 2 bottles of water as compensation. Later the hotel manager reached out with a lovely apology and refund for part of our stay which was appreciated. Some work to do that’s for sure but potential
Stayed 1 night in Sep 2025

10/10 Excellent

Elizabeth

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Recently renovated, larger room and bath than a standard Manhattan room, close to multiple subway lines. Very nice staff and helpful.
9/11 Memorial
Frick Museum cafe
Grand Central and Chrysler Building. Near to hotel.
Stayed 2 nights in Sep 2025

2/10 Terrible

James

Disliked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 3 nights in Sep 2025

10/10 Excellent

Michael

Traveled with group
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Chemists club stay August 2025

We rented 3 rooms at the Chemists Club and we were all impressed with the rooms, the cleanliness, the restaurant that had amazing breakfast available for a nominal price . I chose this hotel for the location and the reviews and would definitely stay there again. The staff was super helpful, kind and courteous.
Stayed 3 nights in Aug 2025

10/10 Excellent

Brenda

Stayed 2 nights in Sep 2025

10/10 Excellent

Verified traveler

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 3 nights in Aug 2025

10/10 Excellent

Scott

Stayed 1 night in Sep 2025

10/10 Excellent

Shaun

Stayed 2 nights in Aug 2025

8/10 Good

Nadia

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Aug 2025

10/10 Excellent

Ryan

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice.
Stayed 1 night in Aug 2025

6/10 Okay

Nicole

Stayed 2 nights in Aug 2025

10/10 Excellent

Charles

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Staff was amazing and friendly and loved the convenience of the location. Quiet street right in the heart of Manhattan
Stayed 2 nights in Aug 2025

8/10 Good

Angela

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Overall good — nice, BIG room for NYC and it’s nicely renovated. Staff was nice as well. Super convenient to Grand Central Station. WiFi was good. Loved that they had ESPN and ESPN2. Opportunities: I didn’t like that there was no security in the elevator where you have to have a key card to get in. Anybody could get in the elevator and go up to any floor. Also, it would’ve been nice to have more washcloths which I did request. Also, it would’ve been nice to have been asked or have the service where we could’ve gotten help getting tickets to shows, etc..
Stayed 4 nights in Aug 2025

10/10 Excellent

Victor

Traveled with group
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Comfortable boutique hotel, great location, really enjoyed Benjamins firndunner and enjoyed Benjamins for breakfast.
Stayed 4 nights in Aug 2025

10/10 Excellent

Natalya

Liked: Cleanliness, staff & service
Excellent hotel and staff! Clean and quiet room.
Stayed 1 night in Aug 2025

10/10 Excellent

John

Liked: Cleanliness, staff & service, property conditions & facilities
Great hotel that is One block away from Grand Central Station. Benjamin Steakhouse Prime is around the corner and is delicious. Not the one connected to the hotel.
Stayed 4 nights in Jul 2025

10/10 Excellent

Gino, Laguna Niguel

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Access to Grand Central Station and the historical aspect of the property
Stayed 6 nights in Aug 2025

10/10 Excellent

Ksenija, Baltimore

Traveled with family and small children
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excellent experience
Stayed 1 night in Aug 2025

10/10 Excellent

Verified traveler

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Exceeded expectations

Stayed 2 nights in Jul 2025

10/10 Excellent

Hussam

Traveled with family and small children
Liked: Cleanliness, property conditions & facilities
the room was soooo beautiful
Stayed 2 nights in Jun 2025

10/10 Excellent

Andrea

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Lovely, well-appointed hotel with helpful, professional staff in a convenient location
Stayed 1 night in Aug 2025

10/10 Excellent

Jennifer

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

So glad I trusted the reviews...

To say this hotel is a hidden gem would be an understatement. I have stayed in dozens of nice hotels in NYC and this far surpassed all of them. My room was twice the size of any room I've ever had. Giant marble bathroom, great bed and a gorgeous room. Honestly I was shocked. The staff was so friendly and the hotel was quiet. I have never stayed in the midtown area but my daughter moved to Murray Hill and The Chemists'Club had great reviews. I was skeptical, but it truly was amazing. I will be staying here from now on. Highly recommend if you need to stay in the Midtown area.
Stayed 1 night in Aug 2025

10/10 Excellent

Brandon

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Aug 2025

10/10 Excellent

Anna Cecilia

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Jul 2025