
$132 Cheap flight deals from Des Moines (DSM) to Siesta Key (SRQ)
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Airfares from $132 One Way, $301 Round Trip from Des Moines to Siesta Key
Prices starting at $301 for return flights and $132 for one-way flights to Siesta Key were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Siesta Key economy flight packages

The Residences at Siesta Key Beach by Hyatt Vacation Club
Dec 5 - Dec 8
Des Moines (DSM) to Sarasota (SRQ)
Sarasota (SRQ) to Des Moines (DSM)
Reviewed on May 10, 2025

The Avalon Club
Dec 27 - Dec 30
Des Moines (DSM) to Tampa (TPA)
Tampa (TPA) to Des Moines (DSM)
Reviewed on Aug 17, 2025

Ocean Club Treasure Island Hotel
Dec 22 - Dec 28
Des Moines (DSM) to Tampa (TPA)
Reviewed on Oct 22, 2025
More About Flying To Siesta Key from Des Moines
Route Information for Flights from Des Moines to Siesta Key
Origin Airport IATA Code | DSM |
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Destination Airport IATA Code | SRQ |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Des Moines to Siesta Key
If you are looking online for bargain Des Moines to Siesta Key flights, Orbitz is your ideal destination. We understand that vacations can be expensive and offer guaranteed low prices on our domestic and international tickets.
Orbitz Uses Cutting-Edge Mobile Tools
Orbitz may offer low cost Des Moines to Siesta Key flights but this does not mean that we skimp on giving you the latest mobile apps. You don’t have to worry about checking your flight status as we send the info for your flights from Des Moines to Siesta Key directly to your smartphone.
Fly Cheap and Earn Miles on Your Des Moines to Siesta Key Flights
Frequent flyer miles and points are great—and even better when you earn them on cheap flights from Des Moines to Siesta Key. With Orbitz, you can earn miles for your frequent flyer program on qualified flights. Enter your frequent flyer number when you book with us to get rewarded for your flight.
Orbitz Takes the Hassle Out Of Flying
We know that flying can be stressful, particularly if you are traveling with young children. That’s why we make sure you are aware of any changes or delays to your flights from Des Moines to Siesta Key via your phone or email address. We can even inform family members too.
Orbitz Flights Fit Around Your Lifestyle
Orbitz understands that you don’t necessarily want to fly at 5:00 a.m—and that sometimes you do. This is why we allow you to find the best Des Moines to Siesta Key flights at the times you want with ease.
Flights from Des Moines
- Des Moines to Houston
- Des Moines to Dallas
- Des Moines to Atlanta
- Des Moines to Phoenix
- Des Moines to Orlando
- Des Moines to Seattle
- Des Moines to Chicago
- Des Moines to Los Angeles
- Des Moines to New York
- Des Moines to Charlotte
- Des Moines to Detroit
- Des Moines to Washington
- Des Moines to London
- Des Moines to New Orleans
- Des Moines to Sacramento
- Des Moines to Toronto
- Des Moines to San Francisco
- Des Moines to Rome
- Des Moines to Paris
- Des Moines to Hartford
Des Moines Airports
Siesta Key Airports
- Visit Siesta Key Beach
- Hotels in Siesta Key Village
- Beach Hotels in Lido Key
- Hotels in Sarasota
- Hotels in Aloha Kai
- Hotels near Lido Beach
- Hotels in South Sarasota
- Flights to Sarasota
- Visit St. Armands Circle
- Lido Key vacation rentals
- Hotels near Crescent Beach
- Car rentals in Sarasota
- Oceanfront Hotels in Lido Key
More Destinations
- Flights from Atlantic City to Lido Key
- Flights from Key West to Sarasota
- Flights from Flint to Sarasota
- Flights from Wilmington to Sarasota
- Flights from Islip to Sarasota
- Flights from Atlanta to Sarasota
- Flights from Austin to Sarasota
- Flights from Baltimore to Sarasota
- Flights from Boston to Sarasota
- Flights from Charlotte to Sarasota
- Flights from Chicago to Sarasota
- Flights from Cincinnati to Sarasota
- Flights from Cleveland to Sarasota
- Flights from Columbus to Sarasota
- Flights from Dallas to Sarasota
- Flights from Denver to Sarasota
- Flights from Detroit to Sarasota
- Flights from Houston to Sarasota
- Flights from Indianapolis to Sarasota
- Flights from Kansas City to Sarasota
- Flights from Las Vegas to Sarasota
- Flights from Los Angeles to Sarasota
- Flights from Memphis to Sarasota
- Flights from Miami to Sarasota
- Flights from Minneapolis - St. Paul to Sarasota
- Flights from Montreal to Sarasota
- Flights from Nashville to Sarasota
- Flights from New Orleans to Sarasota
- Flights from New York to Sarasota
- Flights from Orlando to Sarasota
- Flights from Philadelphia to Sarasota
- Flights from Phoenix to Sarasota
- Flights from Portland to Sarasota
- Flights from Raleigh to Sarasota
- Flights from Salt Lake City to Sarasota
- Flights from San Antonio to Sarasota
- Flights from San Francisco to Sarasota
- Flights from Seattle to Sarasota
- Flights from St. Louis to Sarasota
- Flights from Toronto to Sarasota
- Flights from Washington to Sarasota
- Flights from Charleston to Sarasota
- Flights from Hartford to Sarasota
- Flights from Providence to Sarasota
- Flights from Sacramento to Sarasota
- Flights from Portland to Sarasota
- Flights from Melbourne to Sarasota
- Flights from Omaha to Sarasota
- Flights from Plattsburgh to Sarasota
- Flights from Roanoke to Sarasota
- Flights from Myrtle Beach to Sarasota
- Flights from Des Moines to Sarasota
- Flights from Pittsburgh to Sarasota
- Flights from Fort Lauderdale to Sarasota
- Flights from Newark to Sarasota
- Flights from Richmond to Sarasota
- Flights from Burlington to Sarasota
- Flights from Atlantic City to Sarasota
- Flights from Tulsa to Sarasota
- Flights from Pensacola to Sarasota
- Flights from South Bend to Sarasota
- Flights from Manchester to Sarasota
- Flights from Bentonville - Fayetteville to Sarasota
- Flights from Milwaukee to Sarasota
- Flights from Buffalo to Sarasota
- Flights from Madison to Sarasota
- Flights from Fort Myers to Sarasota
- Flights from Norfolk - Virginia Beach to Sarasota
- Flights from Springfield to Sarasota
- Flights from Rochester to Sarasota
- Flights from Greensboro to Sarasota
- Flights from Oklahoma City to Sarasota
- Flights from Akron to Sarasota
- Flights from Dayton to Sarasota
- Flights from Allentown to Sarasota
- Flights from Knoxville to Sarasota
- Flights from Cedar Rapids - Iowa City to Sarasota
- Flights from Birmingham to Sarasota
- Flights from Huntsville to Sarasota
- Flights from Tampa to Sarasota
- Flights from Jacksonville to Sarasota
- Flights from Peoria to Sarasota
- Flights from Fort Wayne to Sarasota
- Flights from Louisville to Sarasota
- Flights from Lexington to Sarasota
- Flights from Grand Rapids to Sarasota
- Flights from Lansing to Sarasota
- Flights from White Plains to Sarasota
- Flights from Albany to Sarasota
- Flights from Savannah to Sarasota
- Flights from Asheville to Sarasota
- Flights from Greenville - Spartanburg to Sarasota
- Flights from Tallahassee to Sarasota
- Flights from Bangor to Sarasota
- Flights from Fargo to Sarasota
- Flights from Sioux Falls to Sarasota
- Flights from Appleton to Sarasota
- Flights from Columbia to Sarasota
- Flights from Chattanooga to Sarasota
- Flights from Palm Beach to Sarasota
- Visit Siesta Key Beach
- Hotels in Siesta Key Village
- Beach Hotels in Lido Key
- Hotels in Sarasota
- Hotels in Aloha Kai
- Hotels near Lido Beach
- Hotels in South Sarasota
- Flights to Sarasota
- Visit St. Armands Circle
- Lido Key vacation rentals
- Hotels near Crescent Beach
- Car rentals in Sarasota
- Oceanfront Hotels in Lido Key
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.


