Cheap flights from DTW to GSP (Detroit Metropolitan Wayne County to Greenville-Spartanburg Intl.)

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Cheap Flights from DTW to GSP starting at $141 One Way, $319 Round Trip

Prices starting at $319 for return flights and $141 for one-way flights to Greenville-Spartanburg Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Oct 18 - Tue, Oct 21
DTW
Detroit
GSP
Greenville
$319 Roundtrip, found 1 day ago
$319
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Sat, Oct 18 from Detroit to Greenville, returning Tue, Oct 21, priced at $319 found 1 day ago
Sat, Oct 18 - Tue, Oct 21
DTW
Detroit
GSP
Greenville
$321 Roundtrip, found 1 day ago
$321
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Oct 18 from Detroit to Greenville, returning Tue, Oct 21, priced at $321 found 1 day ago
Sat, Oct 18 - Tue, Oct 21
DTW
Detroit
GSP
Greenville
$352 Roundtrip, found 1 day ago
$352
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Sat, Oct 18 from Detroit to Greenville, returning Tue, Oct 21, priced at $352 found 1 day ago
Sat, Oct 18 - Tue, Oct 21
DTW
Detroit
GSP
Greenville
$355 Roundtrip, found 1 day ago
$355
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Sat, Oct 18 from Detroit to Greenville, returning Tue, Oct 21, priced at $355 found 1 day ago
Sat, Oct 18 - Tue, Oct 21
DTW
Detroit
GSP
Greenville
$361 Roundtrip, found 1 day ago
$361
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Sat, Oct 18 from Detroit to Greenville, returning Tue, Oct 21, priced at $361 found 1 day ago

Hotel Ideas near Greenville-Spartanburg Intl.

Airport Hotels near Greenville-Spartanburg Intl.

Hampton Inn & Suites Greenville Airport, SC

Hampton Inn & Suites Greenville Airport, SC

2.5 out of 5
128 The Parkway, Greenville, SC
The price is $117 total per night from Oct 5 to Oct 6
$117 total
per night
Oct 5 - Oct 6
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (953 reviews)
"Spacious room"

Reviewed on Sep 21, 2025

Hampton Inn & Suites Greenville Airport, SC
Woodspring Suites Greenville Airport

Woodspring Suites Greenville Airport

2.5 out of 5
205 Entertainment Blvd, Greenville, SC
The price is $87 total per night from Sep 28 to Sep 29
$87 total
per night
Sep 28 - Sep 29
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Haywood Mall and BMW ...
8.4/10 Very Good! (207 reviews)
"The staff was very helpful because our flight got delayed until tomorrow. The room is clean and its close to the airport"

Reviewed on Sep 22, 2025

Woodspring Suites Greenville Airport
Best Western Greenville Airport Inn

Best Western Greenville Airport Inn

2.5 out of 5
5009 Pelham Road, Greenville, SC
The price is $79 total per night from Sep 28 to Sep 29
$79 total
per night
Sep 28 - Sep 29
Stay at this hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.6/10 Good! (1,019 reviews)
"Stay was pretty good, clean, and service was kind. My only thing is half my power outlets weren’t working"

Reviewed on Sep 21, 2025

Best Western Greenville Airport Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Greenville

Comfort Inn & Suites Greer - Greenville

Comfort Inn & Suites Greer - Greenville

2.5 out of 5
1315 W Wade Hampton Blvd, Greer, SC
The price is $112 total per night from Oct 26 to Oct 27
$112 total
per night
Oct 26 - Oct 27
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (685 reviews)
"The staff were so incredibly nice and the breakfast was great. Didn’t care too much for the coffee."

Reviewed on Sep 22, 2025

Comfort Inn & Suites Greer - Greenville
Hampton Inn Greer Greenville, SC

Hampton Inn Greer Greenville, SC

2.5 out of 5
112 N Main Street, Greer, SC
The price is $145 total per night from Sep 28 to Sep 29
$145 total
per night
Sep 28 - Sep 29
Stay at this hotel in Greer. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.6/10 Exceptional! (376 reviews)
"Great hotel in a great location."

Reviewed on Sep 20, 2025

Hampton Inn Greer Greenville, SC
MainStay Suites Greenville Airport

MainStay Suites Greenville Airport

2.5 out of 5
2671 Dry Pocket Rd, Greer, SC
The price is $88 total per night from Sep 27 to Sep 28
$88 total
per night
Sep 27 - Sep 28
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.4/10 Good! (594 reviews)
"No issues 3 day stay"

Reviewed on Sep 22, 2025

MainStay Suites Greenville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Greenville Hotels With Airport Transportation

Holiday Inn Express & Suites Greenville Airport by IHG

Holiday Inn Express & Suites Greenville Airport by IHG

3.5 out of 5
2681 Dry Pocket Road, Greer, SC
The price is $130 total per night from Sep 30 to Oct 1
$130 total
per night
Sep 30 - Oct 1
Stay at this 3.5-star business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (787 reviews)
"Is good for the available breakfast until 10:00am"

Reviewed on Sep 7, 2025

Holiday Inn Express & Suites Greenville Airport by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Greenville

Comfort Inn & Suites Greer - Greenville

Comfort Inn & Suites Greer - Greenville

2.5 out of 5
1315 W Wade Hampton Blvd, Greer, SC
The price is $112 total per night from Oct 26 to Oct 27
$112 total
per night
Oct 26 - Oct 27
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (685 reviews)
"The staff were so incredibly nice and the breakfast was great. Didn’t care too much for the coffee."

Reviewed on Sep 22, 2025

Comfort Inn & Suites Greer - Greenville
Holiday Inn Express & Suites Greenville Airport by IHG

Holiday Inn Express & Suites Greenville Airport by IHG

3.5 out of 5
2681 Dry Pocket Road, Greer, SC
The price is $130 total per night from Sep 30 to Oct 1
$130 total
per night
Sep 30 - Oct 1
Stay at this 3.5-star business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (787 reviews)
"Is good for the available breakfast until 10:00am"

Reviewed on Sep 7, 2025

Holiday Inn Express & Suites Greenville Airport by IHG
Quality Inn

Quality Inn

2.5 out of 5
611 W Wade Hampton Blvd, Greer, SC
The price is $83 total per night from Oct 26 to Oct 27
$83 total
per night
Oct 26 - Oct 27
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
6.6/10 (317 reviews)
Very impressed
"I have to say I was very very impressed with the room we stayed in. The only issue i had was that the jacuzzi tub room i reserved, the tub was smaller than what I anticipated. It could barely fit 2 people. But the room itself was very impressive. And the lady at the front desk was one of the kindest ..."

Reviewed on Aug 10, 2025

Quality Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

DTW to GSP Route Info

Origin Airport
Detroit
Destination Airport
Greer
Number Of Airlines Serving
7
Distance
510 mi
Shortest Flight Departure Time
7:59PM EDT
Shortest Flight Departure Date
Oct 3
DTW Address & GPS
Address:
1 Detroit Metro Airport
Detroit MI, 48242
United States
IATA Code:
DTW
Longitude:
-83.356048
Latitude:
42.207808
Time Zone:
America/New_York
GSP Address & GPS
Address:
2000 GPS Drive, Suite 1
Greenville SC, 29651-9202
United States
IATA Code:
GSP
Longitude:
-82.217053
Latitude:
34.890569
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from Detroit Metropolitan Wayne County Airport (DTW) to GSP?
Delta Air Lines makes going from Detroit to Greenville easy. It offers direct flights from DTW to GSP, so you don't have to stress about swapping aircraft.
What is the shortest flight from Detroit Metro Airport to Roger Milliken Field?
Use the opportunity to sit back and relax on your flight from Detroit to Greenville. The quickest flight time from Detroit Metro Airport to Greenville-Spartanburg Intl. Airport (GSP) is 3 hours and 54 minutes, which gives you more than enough time to indulge in a tipple or lose yourself in a good book.
How many hours flight from Detroit Metro Airport to Greenville-Spartanburg Intl. Airport (GSP)?
There's no excuse not to book a Greer escape when the plane ride from DTW to GSP is just 4 hours and 3 minutes on average. So, go ahead and secure your seat — it's high time you finally took a break.
What airlines have the most flights from Detroit Metro Airport to Greenville-Spartanburg Intl. Airport (GSP)?
Advertising 139 flights each month between DTW and GSP, Delta Air Lines will get you to your destination in comfort and style.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.