$81 Cheap flight deals from Detroit (DTT) to La Mesa (SAN)
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
This Weekend's Flight Deals from Detroit to La Mesa
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $81 One Way, $144 Round Trip from Detroit to La Mesa
Prices starting at $144 for return flights and $81 for one-way flights to La Mesa were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
La Mesa economy flight packages
Coronado Beach Resort
Feb 23 - Feb 26
Detroit (DTW) to San Diego (SAN)
Reviewed on Apr 7, 2024
City24 Hotel Little Italy Mission Hills
Feb 12 - Feb 19
Detroit (DTT) to San Diego (SAN)
Rancho Bernardo Inn
Feb 19 - Feb 23
Detroit (DTT) to San Diego (SAN)
Reviewed on Jul 26, 2025
La Mesa packages with premium economy flights
The Beau Downtown San Diego Gaslamp Quar
Feb 12 - Feb 14
Detroit (DTW) to San Diego (SAN)
Reviewed on Aug 28, 2025
The Sofia Hotel
Feb 12 - Feb 14
Detroit (DTW) to San Diego (SAN)
Reviewed on Jan 5, 2026
Shore House at The Del, LXR Hotels & Resorts
Feb 12 - Feb 14
Detroit (DTW) to San Diego (SAN)
Reviewed on Jul 22, 2024
More About Flying To La Mesa from Detroit
Route Information for Flights from Detroit to La Mesa
Origin Airport IATA Code | DTT |
|---|---|
Destination Airport IATA Code | SAN |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Detroit to La Mesa
Book your trip through Orbitz for the best deals on Detroit to La Mesa flights. With our cutting-edge mobile tools, getting fantastic savings on international or domestic flights or updates on your flight status has never been easier. Find your low-priced flights from Detroit to La Mesa today with Orbitz.
Frequent Flyer Rewards
If you are a member of a frequent flyer program, Orbitz will ensure you get points or miles for your qualifying Detroit to La Mesa flights. Just provide your frequent flyer number or your loyalty program number when booking your flight online with Orbtiz.com.
Flight Deals on the Go
Never miss out on great savings! Get fantastic deals on flights from Detroit to La Mesa on your mobile device with our apps for iPhone, Android, and iPad, or use your mobile Web browser to access m.orbitz.com. Find big discounts on the hotels you want to stay at to go along with your Detroit to La Mesa flights. The app even gives you information for baggage claim and other important flight details.
Free Flight Alerts
With Orbitz, not do you get amazing low-cost deals on Detroit to La Mesa flights, but we can send you flight alerts to your mobile phone or email. Instantly learn about delays to your flights from Detroit to La Mesa, so you can plan ahead and make different travel arrangements if you need to.
Guaranteed low prices for Detroit to La Mesa flights makes Orbitz the perfect online budget travel source.
Flights from Detroit
- Detroit to Orlando
- Detroit to Dallas
- Detroit to New York
- Detroit to Chicago
- Detroit to San Francisco
- Detroit to Houston
- Detroit to New Orleans
- Detroit to Los Angeles
- Detroit to San Diego
- Detroit to London
- Detroit to Washington
- Detroit to Toronto
- Detroit to Paris
- Detroit to Atlantic City
- Detroit to Charlotte
- Detroit to Montreal
- Detroit to Sacramento
- Detroit to Hartford
- Detroit to Beijing
- Detroit to Kansas City
More Destinations
- Flights from Beef Island to El Cajon
- Flights from Fairbanks to El Cajon
- Flights from Guayaquil to El Cajon
- Flights from Houayxay to El Cajon
- Flights from Sitia to El Cajon
- Flights from Beijing to El Cajon
- Flights from Cincinnati to El Cajon
- Flights from Las Vegas to El Cajon
- Flights from Los Angeles to El Cajon
- Flights from Phoenix to El Cajon
- Flights from San Francisco to El Cajon
- Flights from Palmerston North to El Cajon
- Flights from Santa Maria to El Cajon
- Flights from Sainte Marie to El Cajon
- Flights from Saratov to El Cajon
- Flights from San Diego to El Cajon
- Flights from Castries to El Cajon
- Flights from Tarawa to El Cajon
- Flights from Brandon to El Cajon
- Flights from Sohar to El Cajon
- Flights from Dubrovnik to El Cajon
- Flights from Huong Thuy to El Cajon
- Flights from San Andrés to El Cajon
- Flights from Zivinice to El Cajon
- Flights from Myrtle Beach to El Cajon
- Flights from Tulsa to El Cajon
- Flights from Grand Rapids to El Cajon
- Flights from Asheville to El Cajon
- Flights from Murrieta to El Cajon
- Flights from Jaipur District to El Cajon
- Flights from Recife to El Cajon
- Flights from Kochi to El Cajon
- Flights from Huntsville to El Cajon
- Flights from Zhengzhou to El Cajon
- Flights from Depok to El Cajon
- Flights from Artem to El Cajon
- Flights from Kaukura to El Cajon
- Flights from San José del Cabo to El Cajon
- Flights from Merzifon to El Cajon
- Flights from Green Bay to Lemon Grove
- Flights from Boston to Lemon Grove
- Flights from Cleveland to Lemon Grove
- Flights from Denver to Lemon Grove
- Flights from Miami to Lemon Grove
- Flights from San Antonio to Lemon Grove
- Flights from San Francisco to Lemon Grove
- Flights from Seattle to Lemon Grove
- Flights from Washington to Lemon Grove
- Flights from Stockton to Lemon Grove
- Flights from Princeton to Lemon Grove
- Flights from Newport News to Lemon Grove
- Flights from Brasilia (BSB) to San Diego (SEE)
- Flights from Atlanta to San Diego
- Flights from Boston to San Diego
- Flights from Chicago to San Diego
- Flights from Dallas to San Diego
- Flights from Houston to San Diego
- Flights from Las Vegas to San Diego
- Flights from New York to San Diego
- Flights from Phoenix to San Diego
- Flights from Portland to San Diego
- Flights from Salt Lake City to San Diego
- Flights from Sacramento to San Diego
- Flights from San Jose to San Diego
- Flights from Abilene (ABI) to San Diego (MYF)
- Flights from Armidale (ARM) to San Diego (MYF)
- Flights from Bali (BAJ) to San Diego (MYF)
- Flights from Bridgetown (BGI) to San Diego (MYF)
- Flights from Boa Vista Island (BVC) to San Diego (MYF)
- Flights from Chateauroux (CHR) to San Diego (MYF)
- Flights from Cairns (CNS) to San Diego (MYF)
- Flights from Corvallis (CVO) to San Diego (MYF)
- Flights from Kiritimati (CXI) to San Diego (MYF)
- Flights from Da Nang (DAD) to San Diego (MYF)
- Flights from Dothan (DHN) to San Diego (MYF)
- Flights from Dinard (DNR) to San Diego (MYF)
- Flights from Elko (EKO) to San Diego (MYF)
- Flights from Florencia (FLA) to San Diego (MYF)
- Flights from Hayward (HWD) to San Diego (MYF)
- Flights from Wichita (ICT) to San Diego (MYF)
- Flights from Kaitaia (KAT) to San Diego (MYF)
- Flights from Kyiv (KBP) to San Diego (MYF)
- Flights from Karratha (KTA) to San Diego (MYF)
- Flights from Seattle (LKE) to San Diego (MYF)
- Flights from Ciudad de Catamayo (LOH) to San Diego (MYF)
- Flights from Luang Prabang (LPQ) to San Diego (MYF)
- Flights from Monteagudo (MHW) to San Diego (MYF)
- Flights from Minneapolis (MSP) to San Diego (MYF)
- Flights from Maastricht (MST) to San Diego (MYF)
- Flights from Port Lincoln (PLO) to San Diego (MYF)
- Flights from Papeete (PPT) to San Diego (MYF)
- Flights from Rangiroa (RGI) to San Diego (MYF)
- Flights from Rodrigues Island (RRG) to San Diego (MYF)
- Flights from São José do Rio Preto (SJP) to San Diego (MYF)
- Flights from Orange County (SNA) to San Diego (MYF)
- Flights from Stavropol (STW) to San Diego (MYF)
- Flights from Samui Intl. Airport (USM) to San Diego (MYF)
- Flights from Visakhapatnam (VTZ) to San Diego (MYF)
- Flights from Christmas Island (XCH) to San Diego (MYF)
- Flights from Timmins (YTS) to San Diego (MYF)
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.