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Holiday Inn Express & Suites St. Louis South - I-55 by IHG

2.5 star property

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Photo gallery for Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Property amenity
Property amenity
Free daily buffet breakfast
Fitness facility
Exterior

Reviews

9.6 out of 10
Exceptional

Popular amenities

  • Free WiFi
  • Air conditioning

Explore the area

View in a map
4250 Midamerica Lane, St. Louis, MO, 63129
  • Place, Barnes Jewish South Campus
    ‪5 min walk‬
  • Place, Busch Stadium
    ‪16 min drive‬
  • Place, St. Louis Union Station
    ‪18 min drive‬
  • Airport, St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪30 min drive‬

Room options

View all photos for Standard Room, 2 Queen Beds, Accessible (Comm, Bath Shwr Combo)

Room amenity

Standard Room, 2 Queen Beds, Accessible (Comm, Bath Shwr Combo)

9.4 out of 10
Exceptional
(13 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds

View all photos for Standard Room, 2 Queen Beds, Accessible (Mobil Tub)

Standard Room, 2 Queen Beds, Accessible (Mobil Tub) | In-room safe, desk, laptop workspace, blackout drapes

Standard Room, 2 Queen Beds, Accessible (Mobil Tub)

9.6 out of 10
Exceptional
(4 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds

View all photos for Suite, 1 Bedroom (2 Queen, Extra Living Area)

Room amenity

Suite, 1 Bedroom (2 Queen, Extra Living Area)

9.4 out of 10
Exceptional
(28 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 6
  • 2 Queen Beds

View all photos for Standard Room, 1 King Bed, Accessible (Comm, Bath Shower Combo)

Room amenity

Standard Room, 1 King Bed, Accessible (Comm, Bath Shower Combo)

9.0 out of 10
Wonderful
(7 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed

View all photos for Standard Room, 1 King Bed, Accessible (Mobil Roll In Shwr)

Free toiletries, hair dryer, towels, soap

Standard Room, 1 King Bed, Accessible (Mobil Roll In Shwr)

10.0 out of 10
Exceptional
(2 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed (Extra Living, Walk in Shwr)

Suite, 1 King Bed (Extra Living, Walk in Shwr) | In-room safe, desk, laptop workspace, blackout drapes

Suite, 1 King Bed (Extra Living, Walk in Shwr)

9.0 out of 10
Wonderful
(4 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed

View all photos for Standard Room, 1 King Bed (Bath Shwr Combo)

Room amenity

Standard Room, 1 King Bed (Bath Shwr Combo)

9.8 out of 10
Exceptional
(16 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed

View all photos for Standard Room

Standard Room | In-room safe, desk, laptop workspace, blackout drapes

Standard Room

  • 300 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 Twin Bed

View all photos for Suite, 1 King Bed, Accessible (Mobil Tub, Extra Living)

Suite, 1 King Bed, Accessible (Mobil Tub, Extra Living) | In-room safe, desk, laptop workspace, blackout drapes

Suite, 1 King Bed, Accessible (Mobil Tub, Extra Living)

  • 300 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed

View all photos for Standard Room, 2 Queen Beds

Room amenity

Standard Room, 2 Queen Beds

9.4 out of 10
Exceptional
(74 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds

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About the neighborhood

St. Louis

Located within a leisurely stroll of Barnes Jewish South Campus, Holiday Inn Express & Suites St. Louis South - I-55 by IHG is within a few miles (5 km) of BounceU of St. Louis. This 99-room hotel has free breakfast along with conveniences like an indoor pool and a 24-hour gym.

What's nearby

  • Barnes Jewish South Campus - 5 min walk - 0.3 miles
  • Busch Stadium - 16 min drive - 16.9 miles
  • Gateway Arch - 17 min drive - 17.3 miles
  • Enterprise Center - 17 min drive - 16.7 miles
  • St. Louis Union Station - 18 min drive - 16.9 miles

Getting around

  • Kirkwood Station - 17 min drive
  • St. Louis Lambert Intl. Airport (STL) - 32 min drive

Restaurants

  • ‪Burger King - ‬10 min walk
  • ‪McDonald's - ‬5 min drive
  • ‪Popeyes Louisiana Kitchen - ‬4 min walk
  • ‪Hardee's / Red Burrito - ‬11 min walk
  • ‪Rich & Charlie's Italian Restaurant - ‬3 min drive

About this property

Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Guests staying at Holiday Inn Express & Suites St. Louis South - I-55 by IHG enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. Free parking is available if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include meeting rooms, a business center, and a banquet hall.
49-inch flat-screen TVs come with cable channels, and guests can stay connected with free WiFi and wired Internet. Bathrooms have hair dryers and free toiletries. Refrigerators, microwaves, and coffee makers are also available. Housekeeping is available on request.
Recreational amenities at the hotel include an indoor pool and a 24-hour fitness center.

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Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 9:30 AM

Things to do

  • 24-hour gym
  • Indoor pool

Family friendly

  • In-room crib
  • In-room microwave
  • In-room refrigerator
  • Indoor pool

Conveniences

  • 24-hour front desk
  • Safe at front desk
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Housekeeping (daily)

Business services

  • Business center
  • Meeting rooms

Outdoors

  • Pool loungers

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Elevator
  • Stair-free path to entrance
  • Visual alarms in hallways
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible van parking

More

  • 4 floors
  • At least 10% of profits reinvested in community and sustainability
  • Banquet hall
  • No plastic drinking straws
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Free crib

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • 49-inch flat-screen TV with cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Desk
  • Free local calls
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: 2:30 AM
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • Service animals exempt from fees

Children and extra beds

  • Free cribs/infant beds are available

Property payment types

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a fire extinguisher
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
  • Check-in: 3:00 PM
  • Check-out: 11 AM
  • Minimum check-in age: 21
The front desk is open 24 hours a day. Driving? This property offers free parking.

We should mention

Details about charges, deposits, or other important information:

  • This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
  • Charges for extra guests may apply and vary depending on the property's policy.
  • A cash deposit, credit card, or debit card for incidental charges, as well as a government-issued photo ID, may be required at check-in.
  • Special requests are subject to availability at the time of check-in and can't be guaranteed. Certain requests may come with additional charges.
  • This property accepts credit cards. Cash is not accepted. 
  • Onsite safety features include a fire extinguisher.
  • This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG).

Additional information about polices, regulations, and more:

  • Pool access available from 8 AM to 10 PM.
  • Connecting or adjoining rooms can be requested, but all rooms are subject to availability. Contact the property using the phone number on your booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Holiday Inn Express St. Louis South I-55 Hotel
Holiday Inn Express St. Louis South I-55
Inn Express St Louis I55
Holiday Inn Express Suites St. Louis South I 55
Holiday Inn Express Suites St. Louis South I 55 by IHG
Holiday Inn Express Suites St. Louis South I 55 an IHG Hotel
Holiday Inn Express & Suites St. Louis South - I-55 by IHG Hotel

Frequently asked questions

Is a free cancellation option available at Holiday Inn Express & Suites St. Louis South - I-55 by IHG?

Holiday Inn Express & Suites St. Louis South - I-55 by IHG offers free cancellation on select room rates. To learn more, take a look at the cancellation policy on our site.

How much does it cost to stay at Holiday Inn Express & Suites St. Louis South - I-55 by IHG?

As of Mar 13, 2026, prices found for a 1-night stay for 2 adults at Holiday Inn Express & Suites St. Louis South - I-55 by IHG on Apr 5, 2026 start from $152, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

What is there to do close to Holiday Inn Express & Suites St. Louis South - I-55 by IHG?

This hotel is located in St. Louis, close to Grant's Farm, River City Casino, and Jefferson Barracks Historic Park. You'll also find Meramec River and BounceU of St. Louis within a short drive.

Will I be able to park at Holiday Inn Express & Suites St. Louis South - I-55 by IHG?

Yes, self parking is offered for free at the hotel. Accessible parking is also available for guests.

Does Holiday Inn Express & Suites St. Louis South - I-55 by IHG include a casino at the property?

No, Holiday Inn Express & Suites St. Louis South - I-55 by IHG doesn't have a casino.

Will I find an indoor pool at Holiday Inn Express & Suites St. Louis South - I-55 by IHG?

Yes, this hotel has an indoor pool. Guests have pool access between 8 AM and 10 PM.

What amenities will couples enjoy at Holiday Inn Express & Suites St. Louis South - I-55 by IHG?

Couples staying at this hotel will appreciate amenities like free Internet access as well as an indoor pool and a 24-hour fitness facility.

Does Holiday Inn Express & Suites St. Louis South - I-55 by IHG have a hot tub?

No, this hotel doesn't have a spa tub.

Does Holiday Inn Express & Suites St. Louis South - I-55 by IHG feature a restaurant that includes a breakfast menu?

Holiday Inn Express & Suites St. Louis South - I-55 by IHG offers free buffet breakfast each morning though there is no restaurant.

Will Holiday Inn Express & Suites St. Louis South - I-55 by IHG allow pets to stay for free?

No, pets aren't allowed at Holiday Inn Express & Suites St. Louis South - I-55 by IHG though service animals are welcome.

Are there connecting rooms at Holiday Inn Express & Suites St. Louis South - I-55 by IHG?

Yes, this hotel has connecting guestrooms you can book for your group event or vacation.

What is the closest airport to Holiday Inn Express & Suites St. Louis South - I-55 by IHG?

The closest major airport to Holiday Inn Express & Suites St. Louis South - I-55 by IHG is St. Louis Lambert Intl. Airport (STL), which is 26.1 mi away (32 minutes by car). Another top airport is St. Louis, MO (SUS-Spirit of St. Louis), which is located 26.2 mi away (32-minute drive).

Are there rooms with balconies at Holiday Inn Express & Suites St. Louis South - I-55 by IHG?

No, there aren't any guestrooms with balconies at Holiday Inn Express & Suites St. Louis South - I-55 by IHG.

Holiday Inn Express & Suites St. Louis South - I-55 by IHG Reviews

Reviews

9.6

Exceptional

Rating 10 - Excellent. 800 out of 1002 reviews
Rating 8 - Good. 145 out of 1002 reviews
Rating 6 - Okay. 35 out of 1002 reviews
Rating 4 - Poor. 15 out of 1002 reviews
Rating 2 - Terrible. 7 out of 1002 reviews

9.6/10

Cleanliness

9.6/10

Staff & service

9.6/10

Amenities

9.6/10

Property conditions & facilities

Reviews

8/10 Good

Jeffrey

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 4 nights in Dec 2025

4/10 Poor

Dallas

Stayed 1 night in Dec 2025

10/10 Excellent

tiffany

Liked: Cleanliness, amenities, property conditions & facilities
Room was very clean! enjoyed the amenities!
Stayed 1 night in Dec 2025

10/10 Excellent

Melissa

Liked: Cleanliness
Staff was welcoming and helpful at check in. Offered cookies and milk. The room was clean and the breakfast was good too. I would stay again.
Stayed 1 night in Dec 2025

10/10 Excellent

Abbas

Stayed 1 night in Nov 2025

10/10 Excellent

robert, Ames

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The property was excellent. Big shoutout to Taylor who cleaned the snow off my car.
Stayed 2 nights in Nov 2025

8/10 Good

Carly

Liked: Cleanliness, amenities, property conditions & facilities
Overall hotel was clean and nice. Have stayed many times. Cookie hour is a big hit. Only issue is safety. I asked the front desk for a new key after putting my key in the drop box because I forgot something in the room. It was about an hour before checkout time. Instead of looking at my ID and making a new key, or escorting me to the room, they said to just ask housekeeping to let me in. I could have entered any room I wanted to on that floor without question from housekeeping. I find this upsetting and unsafe. That is the oldest scam in the book to enter a room being cleaned or have housekeeping let you in to someone else’s room. A major hotel like this should know better and follow protocol regardless if the front desk doesn’t feel like making a key or double checking an ID. Safety needs to be a top priority for guests.
Stayed 3 nights in Nov 2025

10/10 Excellent

Christopher

Stayed 1 night in Nov 2025

10/10 Excellent

Nancy

Stayed 1 night in Nov 2025

10/10 Excellent

Kalina

Staff was extremely helpful
Stayed 1 night in Nov 2025

10/10 Excellent

Merry

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Exceptional front desk staff! Beautiful property! Excellent room, with spacious bathroom! Everything was perfect!
Stayed 1 night in Nov 2025

10/10 Excellent

Kelly

Liked: Cleanliness
Stayed 1 night in Nov 2025

10/10 Excellent

Robert

Stayed 1 night in Nov 2025

10/10 Excellent

Jessica

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities
Clean room. Parking fine. Staff nice. Breakfast is good. Over all stay was okay. Was disappointed in hotels.com due to their room description. If you need a handicap accesible room, book through the hotel. We ended up in a hearing accesible room instead, even though the description was for a handicap accesible room. Hotel made it right the best they could, but they only had a one bed room when we needed two beds.
Stayed 1 night in Nov 2025

10/10 Excellent

Jamie, RockFalls

Liked: Cleanliness, amenities, property conditions & facilities
Great staff!
Stayed 2 nights in Oct 2025

10/10 Excellent

George

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Oct 2025

6/10 Okay

Michael

Business traveler
Disliked: Staff & service, room comfort
Stayed 3 nights in Oct 2025

10/10 Excellent

Jennifer

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 4 nights in Oct 2025

10/10 Excellent

Zumret

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excellent
Stayed 2 nights in Aug 2025

8/10 Good

Ruth

Liked: Cleanliness, staff & service, property conditions & facilities
cleaning staff was very helpful and I loved the cookies at night
Stayed 4 nights in Oct 2025

10/10 Excellent

Chena

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Very clean safe environment beds were comfortable rooms were nice and clean air-conditioning working well breakfast options for mini cookies in the evening. We’re good. I will stay here again.
Stayed 2 nights in Oct 2025

10/10 Excellent

phillip

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
The Hotel is under 10 years old. It still looks grand opening ready in the lobby and the building. The shower, however has mold under the shelfs and corner's. Needed some help all in all , A nice stay.
Stayed 3 nights in Oct 2025

10/10 Excellent

Ashley

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The hotel was clean. The breakfast is pretty decent. Several different options to choose from. It’s in a quiet part of town. I would definitely stay there again!
Stayed 3 nights in Oct 2025

6/10 Okay

Tera

Stayed 2 nights in Oct 2025

10/10 Excellent

John C

Business traveler
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff was amazing
Stayed 2 nights in Sep 2025

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