Upstate South Carolina Luxury Hotels
Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels
Save 10% or more on select hotels with Insider Prices
Book on the app to instantly earn 5% on 350,000+ hotels
Tomorrow night
Check prices in Upstate South Carolina for tomorrow night, May 17 - May 18Featured Upstate South Carolina Luxury Hotels

The Westin Poinsett Greenville
120 South Main St, Greenville, SC
Free Cancellation
Reserve now, pay when you stay
$179 nightly
The price is $203 total per night
$203 total
May 26 - May 27
Total includes taxes and fees
Guests of The Westin Poinsett Greenville enjoy a gym, free WiFi in public areas, and conference space. Parking is USD 7.50 per day (USD 20 per day for valet parking)—but if you prefer not to drive, catch a ride in the free airport shuttle (available 24 hours). The front desk is staffed 24/7 to help with securing valuables, dry cleaning/laundry, and concierge services. Additional amenities include a business center, express check-in, and express check-out.
Free airport shuttle
Pet friendly

Hyatt Regency Greenville
220 N Main St, Greenville, SC
Free Cancellation
Reserve now, pay when you stay
$127 nightly
The price is $144 total per night
$144 total
May 26 - May 27
Total includes taxes and fees
Hyatt Regency Greenville features a 24-hour gym, free WiFi in public areas, and meeting rooms. Valet parking is offered for USD 30 per day. Multilingual staff at the front desk are standing by 24/7 to help with luggage storage, concierge services, and dry cleaning/laundry. Additional amenities include a conference center, a 24-hour business center, and a seasonal outdoor pool.
Pool
Pet friendly

Sleep Inn at Greenville Convention Cente
231 N Pleasantburg Dr, Greenville, SC
Free Cancellation
Reserve now, pay when you stay
$80 nightly
The price is $90 total per night
$90 total
May 25 - May 26
Total includes taxes and fees
Sleep Inn at Greenville Convention Cente features a gym, free WiFi in public areas, and a business center. There's free parking, and an airport shuttle (available on request) for USD 10.00 per person one-way. The 24-hour front desk has multilingual staff ready to assist with securing valuables and dry cleaning/laundry. Additional amenities include coffee/tea in a common area, a computer station, and free newspapers.
Breakfast included
Parking included

The Bleckley Inn
151 E Church St, Anderson, SC
$247 nightly
The price is $274 total per night
$274 total
May 18 - May 19
Total includes taxes and fees
The Bleckley Inn offers a gym, a rooftop terrace, and free WiFi in public areas. If you decide to drive, there's free parking. Staff members can answer questions about accommodations, and also provide front-desk service during limited hours. Additional amenities include a meeting room, express check-out, and a banquet hall.
Parking included
Free WiFi

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
851 Congaree Rd, Greenville, SC
Free Cancellation
$103 nightly
The price is $113 total per night
$113 total
May 26 - May 27
Total includes taxes and fees
At Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG, guests enjoy features like an indoor pool, a 24-hour gym, and free WiFi in public areas. You can take advantage of free parking, along with a free airport shuttle (available on request). The front desk has multilingual staff on hand 24/7 to help with dry cleaning/laundry, concierge services, and luggage storage. Additional amenities include conference space, a 24-hour business center, and a computer station.
Pool
Free airport shuttle

Red Roof Inn Spartanburg – I-26
6765 Pottery Rd, Spartanburg, SC
Free Cancellation
Reserve now, pay when you stay
$66 nightly
The price is $73 total per night
$73 total
May 31 - Jun 1
Total includes taxes and fees
Guests of Red Roof Inn Spartanburg – I-26 enjoy free WiFi in public areas, coffee in a common area, and laundry facilities. Free parking is available if you drive. Front-desk staff are standing by 24/7 to assist with any requests. This smoke-free hotel also has a vending machine.
Breakfast included
Pet friendly

Quality Inn Clemson near University
3430 Clemson Blvd, Anderson, SC
Free Cancellation
Reserve now, pay when you stay
$61 nightly
The price is $67 total per night
$67 total
Jun 8 - Jun 9
Total includes taxes and fees
Quality Inn Clemson near University features free WiFi in public areas, meeting rooms, and conference space. There's free parking if you drive. The 24-hour front desk has staff standing by to help with dry cleaning or laundry, and answer any questions about the accommodations. Additional amenities include a 24-hour business center, a seasonal outdoor pool, and free newspapers.
Pool
Breakfast included

La Quinta Inn & Suites by Wyndham Greenville Haywood
65 W Orchard Park Dr, Greenville, SC
Free Cancellation
Reserve now, pay when you stay
$85 nightly
The price is $93 total per night
$93 total
May 25 - May 26
Total includes taxes and fees
La Quinta Inn & Suites by Wyndham Greenville Haywood features a gym, free WiFi in public areas, and conference space. A stay here includes free parking. The front desk is staffed 24 hours a day to help with securing valuables and luggage storage. Additional amenities include a business center, a seasonal outdoor pool, and express check-out.
Pool
Breakfast included

Hilton Greenville
45 W Orchard Park Dr, Greenville, SC
Free Cancellation
Reserve now, pay when you stay
$110 nightly
The price is $124 total per night
$124 total
May 26 - May 27
Total includes taxes and fees
Renovated in 2023, Hilton Greenville offers a 24-hour gym, free WiFi in public areas, and meeting rooms. Self parking is available for USD 10 per night. The 24-hour front desk has multilingual staff ready to help with dry cleaning or laundry, and answer any questions about the area. Additional amenities include a conference center, coffee/tea in a common area, and a computer station.
Pet friendly
Free WiFi

Best Western Travelers Rest Greenville
110 Hawkins Rd, Travelers Rest, SC
Free Cancellation
Reserve now, pay when you stay
$97 nightly
The price is $106 total per night
$106 total
May 22 - May 23
Total includes taxes and fees
At Best Western Travelers Rest Greenville, guests enjoy features like an outdoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The 24-hour front desk has multilingual staff ready to help secure valuables, and answer any questions about the area. Additional amenities include a business center, coffee/tea in a common area, and a computer station.
Pool
Breakfast included

Embassy Suites Greenville Golf Resort & Conference Center
670 Verdae Blvd, Greenville, SC
Free Cancellation
Reserve now, pay when you stay
$128 nightly
The price is $145 total per night
$145 total
May 25 - May 26
Total includes taxes and fees
At Embassy Suites Greenville Golf Resort & Conference Center, guests enjoy a golf course, an indoor pool, and an outdoor pool. If you drive, self parking is USD 6 per day, or you can take advantage of the free airport shuttle during limited hours. The front desk has multilingual staff on hand 24/7 to help with securing valuables, luggage storage, and concierge services. Other amenities at this golf resort include a 24-hour gym, free WiFi in public areas, and an outdoor tennis court.
Pool
Breakfast included

Comfort Inn Greenville - Haywood Mall
246 Congaree Road, Greenville, SC
Free Cancellation
Reserve now, pay when you stay
$81 nightly
The price is $92 total per night
$92 total
May 25 - May 26
Total includes taxes and fees
At Comfort Inn Greenville - Haywood Mall, guests have access to a 24-hour gym, free WiFi in public areas, and a 24-hour business center. There's free parking if you drive. The 24-hour front desk has staff standing by to help with luggage storage and dry cleaning/laundry. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and a computer station.
Pool
Breakfast included

Drury Inn & Suites Greenville
10 Carolina Point Pkwy, Greenville, SC
Free Cancellation
Reserve now, pay when you stay
$117 nightly
The price is $129 total per night
$129 total
May 25 - May 26
Total includes taxes and fees
Drury Inn & Suites Greenville features an indoor pool, an outdoor pool, and a gym. You can take advantage of free parking if you drive. Front-desk staff can answer questions 24/7, and assist with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include free WiFi in public areas, a hot tub, and conference space.
Pool
Hot Tub

Days Inn by Wyndham Greenville
60 Roper Mountain Rd, Greenville, SC
Free Cancellation
Reserve now, pay when you stay
$61 nightly
The price is $67 total per night
$67 total
May 21 - May 22
Total includes taxes and fees
Guests of Days Inn by Wyndham Greenville enjoy a 24-hour gym, free WiFi in public areas, and a business center. If you decide to drive, there's free parking. The 24-hour front desk has staff always at the ready. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and laundry facilities.
Pool
Breakfast included

Baymont by Wyndham Anderson Clemson
128 Interstate Blvd, Anderson, SC
Free Cancellation
Reserve now, pay when you stay
$72 nightly
The price is $80 total per night
$80 total
May 22 - May 23
Total includes taxes and fees
Guests staying at Baymont by Wyndham Anderson Clemson enjoy an outdoor pool, a 24-hour gym, and free WiFi in public areas. If you plan to drive, free parking is available. The 24-hour front desk has staff standing by to help with concierge services, and answer any questions about the accommodations. Additional amenities include a business center, coffee/tea in a common area, and a meeting room.
Pool
Breakfast included
Don't see what you're looking for?
See all available properties in Upstate South Carolina
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Upstate South Carolina hotels essential information
Accommodation | 2,658 hotels |
---|---|
Lowest Price | $67 total |
Highest Price | $274 total |
Popular hotels | The Westin Poinsett Greenville, Hyatt Regency Greenville, Sleep Inn at Greenville Convention Cente, The Bleckley Inn, Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG, Red Roof Inn Spartanburg – I-26, Quality Inn Clemson near University, La Quinta Inn & Suites by Wyndham Greenville Haywood, Hilton Greenville, Best Western Travelers Rest Greenville, Embassy Suites Greenville Golf Resort & Conference Center, Comfort Inn Greenville - Haywood Mall, Drury Inn & Suites Greenville, Days Inn by Wyndham Greenville, Baymont by Wyndham Anderson Clemson |
Recent Luxury Hotels Reviews

Hyatt Place Greenville/Downtown
5/5 Excellent
"The bartender was so sweet my first nights stay!!"
A verified traveler stayed at Hyatt Place Greenville/Downtown
Posted 3 days ago
Other Luxury Hotels
Areas Of Upstate South Carolina
Hotels Near
Hotel Themes
Other Popular Accommodations
Top Trending
Hotels
Coastal South Carolina All Inclusive Resorts & HotelsCoastal South Carolina Oceanfront HotelsCarolina Forest Hotel DealsCoastal South Carolina Waterpark Hotels & ResortsGreenville - Spartanburg Hotels with Free Airport ShuttleHotels in Greenville DowntownHotels in Charleston Historic DistrictHotels closest to Myrtle Beach Convention CenterCoastal South Carolina Gay Friendly HotelsHotels closest to Broadway at the BeachHotels in Cherry Grove BeachHotels closest to Coastal Carolina UniversityGreenville Downtown Hotels with BalconiesHotels in Downtown Myrtle BeachEdisto Beach Hotel DealsCharleston Historic District Hotels with Free ParkingCoastal South Carolina Hotels with KitchenettesHotels in West AshleyHotels in Downtown CharlestonHotels closest to Rock Hill Sports & Event CenterHotels closest to Charleston Tanger OutletsHotels closest to Pier at Garden CityCherry Grove Beach Pet Friendly Hotels
Packages